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List of works by John Paul Pezacki

6-Hydroxydopamine Inhibits the Hepatitis C Virus through Alkylation of Host and Viral Proteins and the Induction of Oxidative Stress

scientific article published on 28 September 2016

A Novel p19 Fusion Protein as a Delivery Agent for Short-interfering RNAs

scientific article published on 5 April 2016

A bifunctional nucleoside probe for the inhibition of the human immunodeficiency virus-type 1 reverse transcriptase

scientific article published on 07 April 2020

A conserved miRNA-183 cluster regulates the innate antiviral response

scientific article published on 06 November 2019

A functionalized hydroxydopamine quinone links thiol modification to neuronal cell death

scientific article published on 09 November 2019

A new chemical probe for phosphatidylinositol kinase activity.

scientific article published on 21 May 2014

A small-molecule probe for hepatitis C virus replication that blocks protein folding.

scientific article published on October 2006

ABPP and Host-Virus Interactions

scientific article published on 01 January 2019

Activity-Based Phosphatidylinositol Kinase Probes Detect Changes to Protein-Protein Interactions During Hepatitis C Virus Replication

scientific article published on 6 March 2018

Activity-based profiling of the proteasome pathway during hepatitis C virus infection

scientific article published on 28 August 2015

Activity-based protein profiling identifies a host enzyme, carboxylesterase 1, which is differentially active during hepatitis C virus replication

scientific article

Activity-based protein profiling of host-virus interactions

scientific article published on 22 September 2011

Activity-based protein profiling of the Escherichia coli GlpG rhomboid protein delineates the catalytic core

scientific article

Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe.

scientific article

Activity-based proteome profiling of hepatoma cells during hepatitis C virus replication using protease substrate probes

scientific article

All-fiber CARS microscopy of live cells

scientific article

An enzyme-linked assay for the rapid quantification of microRNAs based on the viral suppressor of RNA silencing protein p19.

scientific article published on February 2011

Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity

scientific article

Assessing antifreeze activity of AFGP 8 using domain recognition software

scientific article published on 10 January 2007

Bidirectional lipid droplet velocities are controlled by differential binding strengths of HCV core DII protein

scientific article

Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

scientific article

Bioorthogonal Reactions Utilizing Nitrones as Versatile Dipoles in Cycloaddition Reactions

scientific article published in 2021

Bioorthogonal labelling of living bacteria using unnatural amino acids containing nitrones and a nitrone derivative of vancomycin

scientific article published in July 2015

Bleomycin is a potent small-molecule inhibitor of hepatitis C virus replication.

scientific article published on September 2006

Carbon-bonded silver nanoparticles: alkyne-functionalized ligands for SERS imaging of mammalian cells

scientific article published on 28 January 2011

Cellular consequences of copper complexes used to catalyze bioorthogonal click reactions.

scientific article

Cellular lipid metabolism is influenced by the coordination environment of copper.

scientific article

Chemical Methods for Probing Virus-Host Proteomic Interactions

scientific article published on 29 June 2016

Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy.

scientific article published on March 2011

Competing roles of microRNA-122 recognition elements in hepatitis C virus RNA.

scientific article published on 24 December 2010

Correction: Chigrinova, M., et al. Kinugasa reactions in water: from green chemistry to bioorthogonal labelling. Molecules 2015, 20, 6959-6969.

scientific article published on 7 May 2015

Cycloadditions of Trans-Cyclooctenes and Nitrones as Tools for Bioorthogonal Labelling

scientific article published on 27 November 2019

Cysteine residues of Carnation Italian Ringspot virus p19 suppressor of RNA silencing maintain global structural integrity and stability for siRNA binding

scientific article published on 31 March 2009

Design and screening of siRNAs against highly structured RNA targets

scientific article published on January 2013

Development of a multiplexed microfluidic proteomic reactor and its application for studying protein-protein interactions

scientific article published on 10 May 2011

Development of nanoparticle probes for multiplex SERS imaging of cell surface proteins

scientific article published on 18 May 2010

Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism.

scientific article

Dual Strain-Promoted Alkyne-Nitrone Cycloadditions for Simultaneous Labeling of Bacterial Peptidoglycans.

scientific article

Dynamics of lipid droplets induced by the hepatitis C virus core protein

scientific article published on August 2010

Effects of pH and salt concentration on the siRNA binding activity of the RNA silencing suppressor protein p19

scientific article published on 04 June 2007

Enhanced specificity of the viral suppressor of RNA silencing protein p19 toward sequestering of human microRNA-122.

scientific article

Evaluation of chemical labeling strategies for monitoring HCV RNA using vibrational microscopy

scientific article

FLEth RNA intercalating probe is a convenient reporter for small interfering RNAs

scientific article published on July 2009

Fluorescence lifetime imaging of alterations to cellular metabolism by domain 2 of the hepatitis C virus core protein

scientific article

Forward-collected simultaneous fluorescence lifetime imaging and coherent anti-Stokes Raman scattering microscopy

scientific article

Fungal natural alkaloid schizocommunin activates the aryl hydrocarbon receptor pathway

scientific article published on 13 May 2019

Gene Expression Profiling of Endoplasmic Reticulum Stress in Hepatitis C Virus-Containing Cells Treated with an Inhibitor of Protein Disulfide Isomerases

article

Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice

scientific article

Genomic effects of polyamide/DNA interactions on mRNA expression

scientific article

Hepatitis C Virus Helicase Binding Activity Monitored through Site-Specific Labeling Using an Expanded Genetic Code

scientific article published on 07 November 2019

Hepatitis C virus and microRNAs: miRed in a host of possibilities.

scientific article published on 12 April 2014

Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis.

scientific article published on 19 November 2013

Host-virus interactions during hepatitis C virus infection: a complex and dynamic molecular biosystem

scientific article published on July 2010

Human serum activates CIDEB-mediated lipid droplet enlargement in hepatoma cells

scientific article published on 24 October 2013

Hydrophobic triaryl-substituted β-lactams as activity-based probes for profiling eukaryotic enzymes and host-pathogen interactions

scientific article published on September 2014

Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening.

scientific article

Imaging nanometer domains of beta-adrenergic receptor complexes on the surface of cardiac myocytes

scientific article published on 7 August 2005

In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism

scientific article published on 16 January 2020

Inhibition of siRNA Binding to a p19 Viral Suppressor of RNA Silencing by Cysteine Alkylation

scientific article published on 01 January 2007

Intracellular imaging of HCV RNA and cellular lipids by using simultaneous two-photon fluorescence and coherent anti-Stokes Raman scattering microscopies

scientific article published on December 2006

Investigating the antiviral role of cell death-inducing DFF45-like effector B in HCV replication

scientific article

Kinetics studies of rapid strain-promoted [3 + 2]-cycloadditions of nitrones with biaryl-aza-cyclooctynone

scientific article published on 7 March 2012

Kinetics studies of rapid strain-promoted [3+2] cycloadditions of nitrones with bicyclo[6.1.0]nonyne

Kinugasa reactions in water: from green chemistry to bioorthogonal labelling

scientific article

Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis

scientific article

Mammalian cell surface imaging with nitrile-functionalized nanoprobes: biophysical characterization of aggregation and polarization anisotropy in SERS imaging

scientific article published on 01 January 2007

MicroRNA-124 Regulates Fatty Acid and Triglyceride Homeostasis

MicroRNA-7 mediates cross-talk between metabolic signaling pathways in the liver. ⬇️

scientific article published on 10 January 2018

MicroRNAs regulate the immunometabolic response to viral infection in the liver

scientific article published on 19 October 2015

Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication

scientific article published on April 2013

Multiplex pathogen detection based on spatially addressable microarrays of barcoded resins

scientific article

Nanoscale aggregation of cellular beta2-adrenergic receptors measured by plasmonic interactions of functionalized nanoparticles.

scientific article

Nanoscale organization of beta2-adrenergic receptor-Venus fusion protein domains on the surface of mammalian cells

scientific article

Near-field scanning fluorescence microscopy study of ion channel clusters in cardiac myocyte membranes

scientific article

Nitrones as dipoles for rapid strain-promoted 1,3-dipolar cycloadditions with cyclooctynes

scientific article published on 23 December 2009

Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

scientific article

Optimally chirped multimodal CARS microscopy based on a single Ti:sapphire oscillator

scientific article

Optimized aqueous Kinugasa reactions for bioorthogonal chemistry applications

scientific article published on 01 February 2020

Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replication

scientific article published on January 2006

Picoliter wells from selective growth of HEK293 cells on chemically modified PDMS surfaces

scientific article published on 16 March 2006

Predicting reactivity for bioorthogonal cycloadditions involving nitrones

scientific article published in 2020

Profiling Kinase Activity during Hepatitis C Virus Replication Using a Wortmannin Probe

scientific article published on 20 August 2015

Quantitative analysis of microRNA in blood serum with protein-facilitated affinity capillary electrophoresis.

scientific article

Rapid Screening and Identification of Living Pathogenic Organisms via Optimized Bioorthogonal Non-canonical Amino Acid Tagging

scientific article published on 17 July 2017

Rates of release of nitric oxide from HbSNO and internal electron transfer

scientific article published in February 2003

Rearrangements and addition reactions of biarylazacyclooctynones and the implications to copper-free click chemistry

scientific article published on 30 April 2013

S-Nitrosylation of Cross-Linked Hemoglobins at β-Cysteine-93: Stabilized Hemoglobins as Nitric Oxide Sources

article published in 2000

SERS detection and boron delivery to cancer cells using carborane labelled nanoparticles

scientific article published on 15 October 2009

Simultaneous quantitative measurement of luciferase reporter activity and cell number in two- and three-dimensional cultures of hepatitis C virus replicons

scientific article published on 30 January 2006

Single laser source for multimodal coherent anti-Stokes Raman scattering microscopy

scientific article

Site-Specific Cross-Linking of a p19 Viral Suppressor of RNA Silencing Protein and Its RNA Targets Using an Expanded Genetic Code

scientific article published on 02 August 2019

Small Molecule Inhibition of Protein Disulfide Isomerase in Neuroblastoma Cells Induces an Oxidative Stress Response and Apoptosis Pathways

scientific article published on 08 August 2019

Soraphen A: A Probe for Investigating the Role of de Novo Lipogenesis during Viral Infection

scientific article published on 16 February 2015

Spectroscopically encoded microspheres for antigen biosensing

scientific article published on 3 May 2007

Stabilized recombinant suppressors of RNA silencing: functional effects of linking monomers of Carnation Italian Ringspot virus p19.

scientific article published on 12 October 2007

Stearoyl-CoA desaturase inhibition blocks formation of hepatitis C virus-induced specialized membranes

scientific article

Strain-promoted cycloadditions involving nitrones and alkynes--rapid tunable reactions for bioorthogonal labeling

scientific article published on 11 July 2014

Strain-promoted cycloadditions of cyclic nitrones with cyclooctynes for labeling human cancer cells

scientific article

Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.

scientific article published on 17 May 2019

Studies of a viral suppressor of RNA silencing p19-CFP fusion protein: a FRET-based probe for sensing double-stranded fluorophore tagged small RNAs

scientific article

Studies of the interaction of the viral suppressor of RNA silencing protein p19 with small RNAs using fluorescence polarization.

scientific article

Studying the RNA silencing pathway with the p19 protein

scientific article

Suppressing RNA silencing with small molecules and the viral suppressor of RNA silencing protein p19.

scientific article published on 14 June 2015

Synthesis and bioorthogonal coupling chemistry of a novel cyclopentenone-containing unnatural tyrosine analogue

scientific article

Synthesis and characterization of CN-modified protein analogues as potential vibrational contrast agents

scientific article

Systems biology methods help develop a better understanding of hepatitis C virus-induced liver injury

scientific article published on July 2012

Taking Aim at Host-Pathogen Interactions

scientific article published on 01 November 2016

The efficacy of siRNAs against hepatitis C virus is strongly influenced by structure and target site accessibility

scientific article published on May 2010

The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication

scientific article published in February 2006

The role of microRNAs in metabolic interactions between viruses and their hosts

scientific article

Three-mode electrochemical sensing of ultralow microRNA levels.

scientific article

Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus

scientific article

Visualization of the delivery and release of small RNAs using genetic code expansion and unnatural RNA-binding proteins

scientific article published on 13 November 2018

microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis

scientific article published on 20 April 2017

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