List of works - Frédéric Perros

A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents

scientific article published on 12 July 2012

A proof of concept for the detection and classification of pulmonary arterial hypertension through breath analysis with a sensor array

scientific article published in September 2013

A study of magnesium deficiency in human and experimental pulmonary hypertension

scientific article published on 01 March 2012

BET Bromodomain Inhibitors and Pulmonary Arterial Hypertension: Take Care of the Heart

scientific article published on 01 November 2019

BMPRII influences the response of pulmonary microvascular endothelial cells to inflammatory mediators

scientific article published on 6 November 2016

Beyond the Lungs: Systemic Manifestations of Pulmonary Arterial Hypertension

scientific article published on 01 January 2020

Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation

scientific article published in July 2009

Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension

scientific article published on 01 February 2019

Bone morphogenetic protein receptor type II and inflammation are bringing old concepts into the new pulmonary arterial hypertension world.

scientific article published in October 2015

Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension.

scientific article published on 18 August 2016

C-kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension.

scientific article

Ca2+ handling remodeling and STIM1L/Orai1/TRPC1/TRPC4 upregulation in monocrotaline-induced right ventricular hypertrophy

scientific article published on 7 April 2018

Characterization of Kcnk3-Mutated Rat, a Novel Model of Pulmonary Hypertension

scientific article published on 26 July 2019

Chemotherapy-induced pulmonary hypertension: role of alkylating agents.

scientific article

Circulating fibrocytes and pulmonary arterial hypertension

scientific article published on 01 January 2012

Comparison of Human and Experimental Pulmonary Veno-Occlusive Disease

scientific article published on 25 March 2020

Corrigendum to "A Simple Method to Assess In Vivo Proliferation in Lung Vasculature with EdU: The Case of MMC-Induced PVOD in Rat".

scientific article

Current insights on the pathogenesis of pulmonary arterial hypertension.

scientific article

Cytotoxic Cells and Granulysin in Pulmonary Arterial Hypertension and Pulmonary Veno-occlusive Disease

scientific article published on 06 December 2012

Dendritic cell recruitment in lesions of human and experimental pulmonary hypertension

scientific article published in March 2007

Description, Staging and Quantification of Pulmonary Artery Angiophagy in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension

scientific article published on 11 November 2020

Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells

scientific article published on 18 September 2015

Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats

scientific article published on 06 August 2010

Diagnosis and Classification of 17 Diseases from 1404 Subjects via Pattern Analysis of Exhaled Molecules

scientific article (publication date: 24 January 2017)

Does Circulating IL-17 Identify a Subset of Patients With Idiopathic Pulmonary Arterial Hypertension?: Response

scientific article published on 01 October 2015

Early Development of Right Ventricular Ischemic Lesions in a Novel Large Animal Model of Acute Right Heart Failure in Chronic Thromboembolic Pulmonary Hypertension

scientific article

Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension.

scientific article published on 20 June 2008

Endothelial-to-Mesenchymal Transition: An Evolving Paradigm and a Promising Therapeutic Target in PAH.

scientific article published on 4 April 2016

Endothelial-to-mesenchymal transition in pulmonary hypertension.

scientific article published on 15 January 2015

Evidence for the involvement of type I interferon in pulmonary arterial hypertension

scientific article published on 13 December 2013

Familial pulmonary arterial hypertension by KDR heterozygous loss of function

scientific article published on 03 April 2020

Fibrous remodeling of the pulmonary venous system in pulmonary arterial hypertension associated with connective tissue diseases

scientific article published in June 2007

Gut-Lung Connection in Pulmonary Arterial Hypertension.

scientific article published in March 2017

Identity crisis in pulmonary arterial hypertension.

scientific article published in January 2018

Imatinib inhibits bone marrow-derived c-kit+ cell mobilisation in hypoxic pulmonary hypertension.

scientific article published on November 2010

Immune dysregulation and endothelial dysfunction in pulmonary arterial hypertension: a complex interplay

scientific article published on March 2014

Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension.

scientific article

Inflammation in Pulmonary Arterial Hypertension

scientific article published on 01 January 2012

Inflammation in pulmonary arterial hypertension.

scientific article

Inflammation in pulmonary hypertension: what we know and what we could logically and safely target first.

scientific article published on 18 April 2014

KCNK3: new gene target for pulmonary hypertension?

scientific article published on 18 April 2014

Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension

scientific article published on 23 February 2012

Loss of KCNK3 is a hallmark of RV hypertrophy/dysfunction associated with pulmonary hypertension.

scientific article published on 19 January 2018

MicroRNA networks in pulmonary arterial hypertension: share mechanisms with cancer?

scientific article

Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models

scientific article published on 30 June 2015

N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats

scientific article

NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension.

scientific article published on 14 February 2018

Nebivolol for Improving Endothelial Dysfunction, Pulmonary Vascular Remodeling, and Right Heart Function in Pulmonary Hypertension

scientific article published in February 2015

Nouvelles approches immunopathologiques de l’hypertension artérielle pulmonaire

scientific article published on 01 April 2011

Nuclear IL-33 regulates soluble ST2 receptor and IL-6 expression in primary human arterial endothelial cells and is decreased in idiopathic pulmonary arterial hypertension

scientific article (publication date: 15 August 2014)

Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.

scientific article published on 04 October 2013

Occupational exposure to organic solvents: a risk factor for pulmonary veno-occlusive disease

scientific article published on 5 November 2015

Phenotype and outcome of PAH patients carrying a TBX4 mutation

scientific article published on 20 February 2020

Physiopathology of pulmonary arterial hypertension. Cellular and molecular aspects

scientific article published in February 2005

Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension

scientific article

Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension.

scientific article published on 24 February 2016

Potassium channels in pulmonary arterial hypertension

scientific article published on 04 September 2015

Proteomic analysis of vascular smooth muscle cells in physiological condition and in pulmonary arterial hypertension: Toward contractile versus synthetic phenotypes.

scientific article published on 25 July 2016

Pulmonary arterial hypertension

scientific article published on 06 July 2013

Pulmonary arterial hypertension in patients treated by dasatinib

scientific article

Pulmonary arterial hypertension: a flavor of autoimmunity

scientific article published in June 2013

Pulmonary capillary haemangiomatosis: a distinct entity?

scientific article published on 27 May 2020

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension

scientific article published on 19 May 2017

Pulmonary hypertension associated with neurofibromatosis type 1

scientific article published on 29 August 2018

Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension

scientific article published on 22 November 2011

Pulmonary microvascular lesions regress in reperfused chronic thromboembolic pulmonary hypertension

scientific article published in March 2015

Pulmonary vascular remodeling patterns and expression of general control nonderepressible 2 (GCN2) in pulmonary veno-occlusive disease.

scientific article published on 4 October 2017

Pulmonary veno-occlusive disease

scientific article published on 23 March 2016

Rescuing BMPR2-driven endothelial dysfunction in PAH: a novel treatment strategy for the future?

scientific article published on 14 June 2017

Respiratory effects of trichloroethylene.

scientific article published in December 2017

Response by Mendes-Ferreira et al to Letter Regarding Article, "Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension"

scientific article published on 12 August 2019

Response to Letter Regarding Article, “Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Model”

scientific article published on 01 April 2016

Role for Runt-related Transcription Factor 2 in Proliferative and Calcified Vascular Lesions in Pulmonary Arterial Hypertension.

scientific article published on 5 May 2016

Role of Endothelium-derived CC Chemokine Ligand 2 in Idiopathic Pulmonary Arterial Hypertension

scientific article published on 06 September 2007

Sirtuin 1 regulates pulmonary artery smooth muscle cell proliferation: role in pulmonary arterial hypertension.

scientific article published on 24 January 2018

Smooth Muscle Phenotype in Idiopathic Pulmonary Hypertension: Hyper-Proliferative but not Cancerous

scientific article published on 22 July 2019

T-helper 17 cell polarization in pulmonary arterial hypertension

scientific article published in June 2015

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension

scientific article

TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways ⬇️

scientific article published on September 24, 2011

Targeting of c-kit+ haematopoietic progenitor cells prevents hypoxic pulmonary hypertension.

scientific article

Tertiary lymphoid organs in infection and autoimmunity

scientific article published on 21 May 2012

The BET Bromodomain Inhibitor I-BET-151 Induces Structural and Functional Alterations of the Heart Mitochondria in Healthy Male Mice and Rats ⬇️

scientific article published on 27 March 2019

The beneficial effect of suramin on monocrotaline-induced pulmonary hypertension in rats

scientific article

The integrated stress response system in cardiovascular disease

scientific article published on 27 February 2018

The role of inflammation and autoimmunity in the pathophysiology of pulmonary arterial hypertension.

scientific article published on February 2013

Transcription factors, transcriptional coregulators, and epigenetic modulation in the control of pulmonary vascular cell phenotype: therapeutic implications for pulmonary hypertension (2015 Grover Conference series).

scientific article published on December 2016

Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension

scientific article published on 20 September 2016

Tyrosine kinase inhibitors in pulmonary arterial hypertension: a double-edge sword?

scientific article published on 13 September 2013

Understanding the Role of CD4+CD25 high (So-Called Regulatory) T Cells in Idiopathic Pulmonary Arterial Hypertension

scientific article published in 2008

Understanding the Similarities and Differences between Hepatic and Pulmonary Veno-Occlusive Disease

scientific article published on 26 March 2019

Use of β-Blockers in Pulmonary Hypertension

scientific article published on April 2017

[Pathophysiology of pulmonary hypertension: advances and prospects].

scientific article

miR-223 reverses experimental pulmonary arterial hypertension

scientific article published on 17 June 2015

β-blockers in pulmonary arterial hypertension: generation might matter

scientific article published on 01 February 2016

List of works by Frédéric Perros

A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents

A proof of concept for the detection and classification of pulmonary arterial hypertension through breath analysis with a sensor array

A study of magnesium deficiency in human and experimental pulmonary hypertension

BET Bromodomain Inhibitors and Pulmonary Arterial Hypertension: Take Care of the Heart

BMPRII influences the response of pulmonary microvascular endothelial cells to inflammatory mediators

Beyond the Lungs: Systemic Manifestations of Pulmonary Arterial Hypertension

Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation

Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension

Bone morphogenetic protein receptor type II and inflammation are bringing old concepts into the new pulmonary arterial hypertension world.

Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension.

C-kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension.

Ca2+ handling remodeling and STIM1L/Orai1/TRPC1/TRPC4 upregulation in monocrotaline-induced right ventricular hypertrophy

Characterization of Kcnk3-Mutated Rat, a Novel Model of Pulmonary Hypertension

Chemotherapy-induced pulmonary hypertension: role of alkylating agents.

Circulating fibrocytes and pulmonary arterial hypertension

Comparison of Human and Experimental Pulmonary Veno-Occlusive Disease

Corrigendum to "A Simple Method to Assess In Vivo Proliferation in Lung Vasculature with EdU: The Case of MMC-Induced PVOD in Rat".

Current insights on the pathogenesis of pulmonary arterial hypertension.

Cytotoxic Cells and Granulysin in Pulmonary Arterial Hypertension and Pulmonary Veno-occlusive Disease

Dendritic cell recruitment in lesions of human and experimental pulmonary hypertension

Description, Staging and Quantification of Pulmonary Artery Angiophagy in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension

Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells

Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats

Diagnosis and Classification of 17 Diseases from 1404 Subjects via Pattern Analysis of Exhaled Molecules

Does Circulating IL-17 Identify a Subset of Patients With Idiopathic Pulmonary Arterial Hypertension?: Response

Early Development of Right Ventricular Ischemic Lesions in a Novel Large Animal Model of Acute Right Heart Failure in Chronic Thromboembolic Pulmonary Hypertension

Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension.

Endothelial-to-Mesenchymal Transition: An Evolving Paradigm and a Promising Therapeutic Target in PAH.

Endothelial-to-mesenchymal transition in pulmonary hypertension.

Evidence for the involvement of type I interferon in pulmonary arterial hypertension

Familial pulmonary arterial hypertension by KDR heterozygous loss of function

Fibrous remodeling of the pulmonary venous system in pulmonary arterial hypertension associated with connective tissue diseases

Gut-Lung Connection in Pulmonary Arterial Hypertension.

Identity crisis in pulmonary arterial hypertension.

Imatinib inhibits bone marrow-derived c-kit+ cell mobilisation in hypoxic pulmonary hypertension.

Immune dysregulation and endothelial dysfunction in pulmonary arterial hypertension: a complex interplay

Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension.

Inflammation in Pulmonary Arterial Hypertension

Inflammation in pulmonary arterial hypertension.

Inflammation in pulmonary hypertension: what we know and what we could logically and safely target first.

KCNK3: new gene target for pulmonary hypertension?

Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension

Loss of KCNK3 is a hallmark of RV hypertrophy/dysfunction associated with pulmonary hypertension.

MicroRNA networks in pulmonary arterial hypertension: share mechanisms with cancer?

Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models

N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats

NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension.

Nebivolol for Improving Endothelial Dysfunction, Pulmonary Vascular Remodeling, and Right Heart Function in Pulmonary Hypertension

Nouvelles approches immunopathologiques de l’hypertension artérielle pulmonaire

Nuclear IL-33 regulates soluble ST2 receptor and IL-6 expression in primary human arterial endothelial cells and is decreased in idiopathic pulmonary arterial hypertension

Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.

Occupational exposure to organic solvents: a risk factor for pulmonary veno-occlusive disease

Phenotype and outcome of PAH patients carrying a TBX4 mutation

Physiopathology of pulmonary arterial hypertension. Cellular and molecular aspects

Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension

Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension.

Potassium channels in pulmonary arterial hypertension

Proteomic analysis of vascular smooth muscle cells in physiological condition and in pulmonary arterial hypertension: Toward contractile versus synthetic phenotypes.

Pulmonary arterial hypertension

Pulmonary arterial hypertension in patients treated by dasatinib

Pulmonary arterial hypertension: a flavor of autoimmunity

Pulmonary capillary haemangiomatosis: a distinct entity?

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension

Pulmonary hypertension associated with neurofibromatosis type 1

Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension

Pulmonary microvascular lesions regress in reperfused chronic thromboembolic pulmonary hypertension

Pulmonary vascular remodeling patterns and expression of general control nonderepressible 2 (GCN2) in pulmonary veno-occlusive disease.

Pulmonary veno-occlusive disease

Rescuing BMPR2-driven endothelial dysfunction in PAH: a novel treatment strategy for the future?

Respiratory effects of trichloroethylene.

Response by Mendes-Ferreira et al to Letter Regarding Article, "Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension"

Response to Letter Regarding Article, “Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Model”

Role for Runt-related Transcription Factor 2 in Proliferative and Calcified Vascular Lesions in Pulmonary Arterial Hypertension.

Role of Endothelium-derived CC Chemokine Ligand 2 in Idiopathic Pulmonary Arterial Hypertension

Sirtuin 1 regulates pulmonary artery smooth muscle cell proliferation: role in pulmonary arterial hypertension.

Smooth Muscle Phenotype in Idiopathic Pulmonary Hypertension: Hyper-Proliferative but not Cancerous

T-helper 17 cell polarization in pulmonary arterial hypertension

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension

TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways ⬇️