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List of works by Laura A Marlow

Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target.

scientific article published on 12 February 2015

Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

scientific article published on 6 October 2017

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

scientific article (publication date: 24 January 2003)

An Effective Personalized Approach to a Rare Tumor: Prolonged Survival in Metastatic Pancreatic Acinar Cell Carcinoma Based on Genetic Analysis and Cell Line Development ⬇️

scientific article published on March 8, 2011

Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies

scientific article

Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP).

scientific article published in January 2003

Cytoplasmic sequestration of p27 via AKT phosphorylation in renal cell carcinoma.

scientific article

Detailed Molecular Fingerprinting of Four New Anaplastic Thyroid Carcinoma Cell Lines and Their Use for Verification of RhoB as a Molecular Therapeutic Target ⬇️

scientific article published on September 1, 2010

Foxo3a drives proliferation in anaplastic thyroid carcinoma via transcriptional regulation of cyclin A1: A paradigm shift that impacts current therapeutic strategies ⬇️

scientific article published on June 20, 2012

Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration.

scientific article

High-grade endometrial stromal sarcoma as the initial presentation of an adult patient with Peutz-Jeghers Syndrome: a case report.

scientific article

Hypoxia negatively regulates heparan sulfatase 2 expression in renal cancer cell lines ⬇️

scientific article published on July 7, 2011

Loss of type III transforming growth factor-beta receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma

scientific article published on 08 March 2010

Molecular diagnosis of a BRAF papillary thyroid carcinoma with multiple chromosome abnormalities and rare adrenal and hypothalamic metastases.

scientific article published on December 2006

Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4

scientific article

Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1.

scientific article published on April 2006

Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin

scientific article published on 10 May 2016

Osteopontin is a multi-faceted pro-tumorigenic driver for central nervous system lymphoma.

scientific article published on April 2016

Pathway signature and cellular differentiation in clear cell renal cell carcinoma

scientific article

Pazopanib Enhances Paclitaxel-Induced Mitotic Catastrophe in Anaplastic Thyroid Cancer ⬇️

scientific article published on January 2, 2013

Preclinical evaluation of the mTOR inhibitor, temsirolimus, in combination with the epothilone B analog, ixabepilone in renal cell carcinoma ⬇️

scientific article published on August 14, 2013

Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma

scientific article

Reactivation of suppressed RhoB is a critical step for the inhibition of anaplastic thyroid cancer growth

scientific article

Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers.

scientific article published on 23 July 2012

RhoB mediates antitumor synergy of combined ixabepilone and sunitinib in human ovarian serous cancer ⬇️

scientific article published on November 22, 2011

RhoB upregulation leads to either apoptosis or cytostasis through differential target selection.

scientific article

S100A8 is a novel therapeutic target for anaplastic thyroid carcinoma

scientific article

Selective central nervous system tropism of primary central nervous system lymphoma.

scientific article

Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma ⬇️

scientific article published on April 30, 2013

Targeting the cyclin dependent kinase and retinoblastoma axis overcomes standard of care resistance in BRAF V600E -mutant melanoma

scientific article published on 23 December 2017

The combination of an mTORc1/TORc2 inhibitor with lapatinib is synergistic in bladder cancer in vitro

scientific article

p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression.

scientific article published on November 2008

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