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List of works by Christopher Redfern

13-cis retinoic acid and isomerisation in paediatric oncology--is changing shape the key to success?

scientific article

A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor

scientific article published on 10 April 2019

A common intron 2 polymorphism of the glucocorticoid receptor gene is associated with insulin resistance in men.

scientific article

An evaluation of canes as a management technique to reduce predation by gulls of ground‐nesting seabirds

scientific article published in 2019

Association of glucocorticoid receptor polymorphism A3669G in exon 9beta with reduced central adiposity in women

scientific article published on 01 May 2006

Azathioprine with Allopurinol: Lower Deoxythioguanosine in DNA and Transcriptome Changes Indicate Mechanistic Differences to Azathioprine Alone.

scientific article published on 27 April 2017

COX2 expression in neuroblastoma increases tumorigenicity but does not affect cell death in response to the COX2 inhibitor celecoxib

scientific article

Celecoxib prevents neuroblastoma tumor development and potentiates the effect of chemotherapeutic drugs in vitro and in vivo.

scientific article published on February 2007

Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells

scientific article

Changes in functional properties of the caffeine-sensitive Ca2+ store during differentiation of human SH-SY5Y neuroblastoma cells.

scientific article published on 17 August 2006

Changes in oncogene mRNA expression during human keratinocyte differentiation

scientific article published on 01 January 1994

Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma

scientific article

Concentration-dependent effects of 9-cis retinoic acid on neuroblastoma differentiation and proliferation in vitro

scientific article published on 01 November 1994

Cytogenetic differences and neuroblastoma cell interconversion

scientific article published on 01 March 2004

Differential effects of retinoic acid isomers on the expression of nuclear receptor co-regulators in neuroblastoma

scientific article published on 01 February 1999

Differentiation-Induced Remodelling of Store-Operated Calcium Entry Is Independent of Neuronal or Glial Phenotype but Modulated by Cellular Context

scientific article published on 26 May 2018

Distinct properties of fenretinide and CD437 lead to synergistic responses with chemotherapeutic reagents

scientific article published on 01 December 2000

Effect of insulin upon protein degradation in cultured human myocytes

scientific article published on 01 October 2003

Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death.

scientific article

Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways

scientific article published on 13 February 2019

Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide.

scientific article

Gene expression and neuroblastoma cell Differentiation in response to retinoic acid: Differential effects of 9-cis and all-trans retinoic acid ⬇️

scientific article published on January 1, 1995

Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids ⬇️

scientific article published on 02 May 2019

Growth and DNA damage-inducible transcription factor 153 mediates apoptosis in response to fenretinide but not synergy between fenretinide and chemotherapeutic drugs in neuroblastoma.

scientific article published on December 2003

Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.

scientific article published on 31 January 2011

Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.

scientific article

Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells

scientific article published on February 2005

Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78.

scientific article published on 27 June 2013

Isolation of Retinoid Receptors from Manimalian Cells ⬇️

scientific article published on January 1, 1998

Ligand binding properties of human cellular retinoic acid binding protein II expressed in E. coli as a glutathione-S-transferase fusion protein.

scientific article

Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients

scientific article

Low prevalence of the N363S polymorphism of the glucocorticoid receptor in South Asians living in the United Kingdom

scientific article published on 01 January 2004

Molecular markers of retinoid activity in skin

scientific article published on 01 January 1994

Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo.

scientific article published on 8 May 2007

NFkappaB modulators in a model of glucocorticoid resistant, childhood acute lymphoblastic leukemia.

scientific article

Neurogenesis in Response to Synthetic Retinoids at Different Temporal Scales.

scientific article published on 27 February 2017

Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.

scientific article published on 26 January 2011

Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma.

scientific article published on November 2013

Outcome of the p53-mediated DNA damage response in neuroblastoma is determined by morphological subtype and MYCN expression.

scientific article

Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids

scientific article published on 10 February 2018

Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition

scientific article published on 27 August 2015

RXR beta isoforms in neuroblastoma cells and evidence for a novel 3'-end transcript.

scientific article published on September 2001

Receptor mechanisms mediating differentiation and proliferation effects of retinoids on neuroblastoma cells

scientific article published on 01 January 2000

Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells

scientific article

Release and sequestration of Ca2+ by a caffeine- and ryanodine-sensitive store in a sub-population of human SH-SY5Y neuroblastoma cells.

scientific article published in August 2005

Relevance of nonsynonymous CYP2C8 polymorphisms to 13-cis retinoic acid and paclitaxel hydroxylation.

scientific article published on 26 April 2010

Retinoic acid receptor expression during the in vitro differentiation of human neuroblastoma

scientific article published on 01 November 1993

Retinoic acid receptors and retinoid binding proteins in endometrial adenocarcinoma: differential expression of cellular retinoid binding proteins in endometrioid tumours

scientific article published on 01 August 1995

Retinoid-induced differentiation of neuroblastoma: comparison between LG69, an RXR-selective analogue and 9-cis retinoic acid

scientific article published on 01 January 1998

Retinoids in neuroblastoma therapy: distinct biological properties of 9-cis- and all-trans-retinoic acid.

scientific article

Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) for Cellular Retinoid-Binding Proteins ⬇️

scientific article published on January 1, 1998

Sodium bicarbonate treatment and ubiquitin gene expression in acidotic human subjects with chronic renal failure.

scientific article published in July 2002

Store-operated Ca2+ entry in proliferating and retinoic acid-differentiated N- and S-type neuroblastoma cells ⬇️

scientific article published on December 6, 2012

Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs

scientific article published on 01 December 2000

Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates.

scientific article

Synthesis and biological evaluation of 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26).

scientific article

Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.

scientific article

Targeting GRP78 to enhance melanoma cell death.

scientific article published on 12 July 2010

Targeting X-linked inhibitor of apoptosis protein to increase the efficacy of endoplasmic reticulum stress-induced apoptosis for melanoma therapy.

scientific article published on 3 June 2010

The N363S polymorphism of the glucocorticoid receptor: potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus.

scientific article

The NF-kappaB pathway mediates fenretinide-induced apoptosis in SH-SY5Y neuroblastoma cells.

scientific article

The impact of retinoic acid treatment on the sensitivity of neuroblastoma cells to fenretinide

scientific article published on 29 September 2011

The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors

The role of gangliosides in fenretinide-induced apoptosis of neuroblastoma.

scientific article

Three Faces of Mercaptopurine Cytotoxicity In Vitro: Methylation, Nucleotide Homeostasis, and Deoxythioguanosine in DNA

scientific article published on 08 June 2018

[31] Cellular retinoic acid-binding protein from neonatal rat skin: Purification and analysis

scientific article published on 01 January 1990

p38MAPK-Dependent sensitivity of Ewing's sarcoma family of tumors to fenretinide-induced cell death

scientific article (publication date: 15 April 2005)

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