List of works - Shane M Devine

A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells

scientific article published on 12 November 2019

A Structure-Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists

scientific article published on 15 February 2018

An allosteric modulator of the adenosine A1 receptor improves cardiac function following ischaemia in murine isolated hearts.

scientific article published on 12 April 2013

Antimalarial drug discovery targeting apical membrane antigen 1

Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK.

scientific article

Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening

article

Dual acting antioxidant A1 adenosine receptor agonists.

scientific article published on 25 July 2007

Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe

scientific article published on 13 February 2019

Ligand-induced conformational change of Plasmodium falciparum AMA1 detected using 19F NMR.

scientific article published on 5 August 2014

Molecular mechanisms of bitopic ligand engagement with the M1 muscarinic acetylcholine receptor

scientific article

Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against Plasmodium falciparum

scientific article published on 13 December 2019

Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold.

scientific article published on 16 January 2015

Reverse engineering of the selective agonist TBPB unveils both orthosteric and allosteric modes of action at the M₁ muscarinic acetylcholine receptor.

scientific article

Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials

scientific article published on 24 January 2016

Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO

scientific article

Synthesis and Pharmacological Evaluation of Noscapine-Inspired 5-Substituted Tetrahydroisoquinolines as Cytotoxic Agents

scientific article published on 14 September 2018

Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptor.

scientific article published on 17 February 2012

Synthesis and evaluation of new N6-substituted adenosine-5'-N-methylcarboxamides as A3 adenosine receptor agonists.

scientific article published on 27 March 2010

The Development Process for Discovery and Clinical Advancement of Modern Antimalarials

scientific article published on 20 August 2019

VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.

scientific article published on 5 July 2016

List of works by Shane M Devine

A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells

A Structure-Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists

An allosteric modulator of the adenosine A1 receptor improves cardiac function following ischaemia in murine isolated hearts.

Antimalarial drug discovery targeting apical membrane antigen 1

Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK.

Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening

Dual acting antioxidant A1 adenosine receptor agonists.

Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe

Ligand-induced conformational change of Plasmodium falciparum AMA1 detected using 19F NMR.

Molecular mechanisms of bitopic ligand engagement with the M1 muscarinic acetylcholine receptor

Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against Plasmodium falciparum

Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold.

Reverse engineering of the selective agonist TBPB unveils both orthosteric and allosteric modes of action at the M₁ muscarinic acetylcholine receptor.

Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials

Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO

Synthesis and Pharmacological Evaluation of Noscapine-Inspired 5-Substituted Tetrahydroisoquinolines as Cytotoxic Agents

Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptor.

Synthesis and evaluation of new N6-substituted adenosine-5'-N-methylcarboxamides as A3 adenosine receptor agonists.

The Development Process for Discovery and Clinical Advancement of Modern Antimalarials

VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.