List of works - Timothy D Williams

A DNA expression array to detect toxic stress response in European flounder (Platichthys flesus).

scientific article published in October 2003

Adaptive differences in gene expression in European flounder (Platichthys flesus)

article

Comparative ovarian microarray analysis of juvenile hormone-responsive genes in water flea Daphnia magna: potential targets for toxicity

scientific article published on 24 August 2016

Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis.

scientific article

Construction of subtracted EST and normalised cDNA libraries from liver of chemical-exposed three-spined stickleback (Gasterosteus aculeatus) containing pollutant-responsive genes as a resource for transcriptome analysis

scientific article

DNA methylation in liver tumorigenesis in fish from the environment.

scientific article published in November 2011

Defensive and adverse energy-related molecular responses precede tris (1, 3-dichloro-2-propyl) phosphate cytotoxicity.

scientific article published on 15 July 2015

Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water

scientific article published on 09 July 2017

Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose.

scientific article published in October 2006

Estimating the efficiency of fish cross-species cDNA microarray hybridization.

scientific article published on 20 May 2007

Gene expression analyses of hepatocellular adenoma and hepatocellular carcinoma from the marine flatfish Limanda limanda

scientific article published in January 2010

Gene expression and epigenetic changes by furan in rat liver ⬇️

scientific article published on November 3, 2011

Gene expression and metabolic responses of HepG2/C3A cells exposed to flame retardants and dust extracts at concentrations relevant to indoor environmental exposures.

scientific article published on 6 November 2015

Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol.

scientific article published on 4 May 2007

Hepatic gene expression in flounder chronically exposed to multiply polluted estuarine sediment: Absence of classical exposure 'biomarker' signals and induction of inflammatory, innate immune and apoptotic pathways.

scientific article published on 10 November 2009

Hepatic transcriptional responses to copper in the three-spined stickleback are affected by their pollution exposure history.

scientific article published on 31 December 2016

Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol.

scientific article

Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene.

scientific article

Hepatic transcriptomic profiles of European flounder (Platichthys flesus) from field sites and computational approaches to predict site from stress gene responses following exposure to model toxicants

scientific article published on 19 August 2008

Immune- and stress-related transcriptomic responses of Solea senegalensis stimulated with lipopolysaccharide and copper sulphate using heterologous cDNA microarrays.

scientific article

Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations.

scientific article published on 27 May 2014

Intraspecific variation in expression of candidate genes for osmoregulation, heme biosynthesis and stress resistance suggests local adaptation in European flounder (Platichthys flesus).

scientific article published on 18 June 2008

Molecular basis of carcinogenicity of tungsten alloy particles

scientific article

Molecular responses of European flounder (Platichthys flesus) chronically exposed to contaminated estuarine sediments.

scientific article

Molecular toxicity of cerium oxide nanoparticles to the freshwater alga Chlamydomonas reinhardtii is associated with supra-environmental exposure concentrations.

scientific article

Oxidative stress response of European flounder (Platichthys flesus) to cadmium determined by a custom cDNA microarray

scientific article published on 09 March 2006

Reactive oxygen species and oxidative DNA damage mediate the cytotoxicity of tungsten-nickel-cobalt alloys in vitro.

scientific article published on 8 October 2010

The cytochrome P450 1A gene (CYP1A) from European flounder (Platichthys flesus), analysis of regulatory regions and development of a dual luciferase reporter gene system.

scientific article

The toxicological application of transcriptomics and epigenomics in zebrafish and other teleosts.

scientific article published on 07 January 2014

Towards a system level understanding of non-model organisms sampled from the environment: a network biology approach

scientific article

Transcriptional responses in neonate and adult Daphnia magna in relation to relative susceptibility to genotoxicants ⬇️

scientific article published on April 30, 2011

Transcriptomic and metabolomic approaches to investigate the molecular responses of human cell lines exposed to the flame retardant hexabromocyclododecane (HBCD).

scientific article published on 27 August 2015

Transcriptomic responses of European flounder (Platichthys flesus) liver to a brominated flame retardant mixture.

scientific article published on 29 July 2013

Transcriptomic responses of European flounder (Platichthys flesus) to model toxicants.

scientific article published on 15 August 2008

cDNA cloning and expression of a cytochrome P450 1A (CYP1A) gene from the hermaphroditic fish Rivulus marmoratus.

scientific article published on 14 July 2005

cDNA cloning of translationally controlled tumor protein/histamine releasing factor (TCTP/HRF) from the intertidal harpacticoid copepod Tigriopus japonicus.

scientific article

List of works by Timothy D Williams

A DNA expression array to detect toxic stress response in European flounder (Platichthys flesus).

Adaptive differences in gene expression in European flounder (Platichthys flesus)

Comparative ovarian microarray analysis of juvenile hormone-responsive genes in water flea Daphnia magna: potential targets for toxicity

Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis.

Construction of subtracted EST and normalised cDNA libraries from liver of chemical-exposed three-spined stickleback (Gasterosteus aculeatus) containing pollutant-responsive genes as a resource for transcriptome analysis

DNA methylation in liver tumorigenesis in fish from the environment.

Defensive and adverse energy-related molecular responses precede tris (1, 3-dichloro-2-propyl) phosphate cytotoxicity.

Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water

Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose.

Estimating the efficiency of fish cross-species cDNA microarray hybridization.

Gene expression analyses of hepatocellular adenoma and hepatocellular carcinoma from the marine flatfish Limanda limanda

Gene expression and epigenetic changes by furan in rat liver ⬇️

Gene expression and metabolic responses of HepG2/C3A cells exposed to flame retardants and dust extracts at concentrations relevant to indoor environmental exposures.

Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol.

Hepatic gene expression in flounder chronically exposed to multiply polluted estuarine sediment: Absence of classical exposure 'biomarker' signals and induction of inflammatory, innate immune and apoptotic pathways.

Hepatic transcriptional responses to copper in the three-spined stickleback are affected by their pollution exposure history.

Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol.

Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene.

Hepatic transcriptomic profiles of European flounder (Platichthys flesus) from field sites and computational approaches to predict site from stress gene responses following exposure to model toxicants

Immune- and stress-related transcriptomic responses of Solea senegalensis stimulated with lipopolysaccharide and copper sulphate using heterologous cDNA microarrays.

Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations.

Intraspecific variation in expression of candidate genes for osmoregulation, heme biosynthesis and stress resistance suggests local adaptation in European flounder (Platichthys flesus).

Molecular basis of carcinogenicity of tungsten alloy particles

Molecular responses of European flounder (Platichthys flesus) chronically exposed to contaminated estuarine sediments.

Molecular toxicity of cerium oxide nanoparticles to the freshwater alga Chlamydomonas reinhardtii is associated with supra-environmental exposure concentrations.

Oxidative stress response of European flounder (Platichthys flesus) to cadmium determined by a custom cDNA microarray

Reactive oxygen species and oxidative DNA damage mediate the cytotoxicity of tungsten-nickel-cobalt alloys in vitro.

The cytochrome P450 1A gene (CYP1A) from European flounder (Platichthys flesus), analysis of regulatory regions and development of a dual luciferase reporter gene system.

The toxicological application of transcriptomics and epigenomics in zebrafish and other teleosts.

Towards a system level understanding of non-model organisms sampled from the environment: a network biology approach

Transcriptional responses in neonate and adult Daphnia magna in relation to relative susceptibility to genotoxicants ⬇️

Transcriptomic and metabolomic approaches to investigate the molecular responses of human cell lines exposed to the flame retardant hexabromocyclododecane (HBCD).

Transcriptomic responses of European flounder (Platichthys flesus) liver to a brominated flame retardant mixture.

Transcriptomic responses of European flounder (Platichthys flesus) to model toxicants.

cDNA cloning and expression of a cytochrome P450 1A (CYP1A) gene from the hermaphroditic fish Rivulus marmoratus.

cDNA cloning of translationally controlled tumor protein/histamine releasing factor (TCTP/HRF) from the intertidal harpacticoid copepod Tigriopus japonicus.