List of works - Antonino Cattaneo

A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.

scientific article published on January 2010

A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor

scientific article published on 11 December 2014

A non-radioactive in situ hybridization method that does not require RNAse-free conditions.

scientific article published in December 1998

A small molecule targeting the multifactorial nature of Alzheimer's disease.

scientific article published in January 2007

Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE

scientific article published on January 2009

Activity-dependent expression of Channelrhodopsin at neuronal synapses

scientific article published on 20 November 2017

Acute cholinergic rescue of synaptic plasticity in the neurodegenerating cortex of anti-nerve-growth-factor mice.

scientific article

Amyloid plaque-independent deficit of early postnatal visual cortical plasticity in the 5XFAD transgenic model of Alzheimer's disease

scientific article published on 01 January 2014

Annual fishes of the genus Nothobranchius as a model system for aging research

scientific article

Assembled IgG molecules are exported from the endoplasmic reticulum in myeloma cells despite the retention signal SEKDEL.

scientific article published on May 1998

Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies

scientific article published in September 2002

Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis.

scientific article

Cloning and expression of an anti-nerve growth factor (NGF) antibody for studies using the neuroantibody approach.

scientific article published on October 1993

Co-expression of TrkB and the N-methyl-D-aspartate receptor subunits NR1-C1, NR2A and NR2B in the rat visual cortex.

scientific article published in January 1999

Conformational plasticity of proNGF

scientific article

Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum.

scientific article

Contrast influence on perceived orientation

scientific article published on 01 January 1982

Corrigendum: Precursor and mature NGF live tracking: one versus many at a time in the axons.

scientific article published on 30 March 2016

Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice.

scientific article

Design and selection of an intrabody library produced de-novo for the non-structural protein NSP5 of rotavirus.

scientific article

Development of a non invasive NGF-based therapy for Alzheimer's disease.

scientific article published on April 2009

Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers

scientific article

Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment

scientific article

Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody

scientific article

Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation.

scientific article published on 11 January 2013

Early inflammation and immune response mRNAs in the brain of AD11 anti-NGF mice.

scientific article published on 14 July 2009

Effects of intrabodies specific for rotavirus NSP5 during the virus replicative cycle.

scientific article

Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer-collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice.

scientific article

Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications

scientific article

Gene expression biomarkers in the brain of a mouse model for Alzheimer's disease: mining of microarray data by logic classification and feature selection

scientific article

Gene expression changes in the motor cortex mediating motor skill learning

scientific article

Gephyrin selective intrabodies as a new strategy for studying inhibitory receptor clustering.

scientific article published on 16 November 2007

IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels

scientific article

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models.

scientific article

Immunosympathectomy as the first phenotypic knockout with antibodies.

scientific article published on 20 March 2013

In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction

scientific article published in January 2010

In vitro receptor binding properties of a "painless" NGF mutein, linked to hereditary sensory autonomic neuropathy type V.

scientific article

In vivo selection of intrabodies specifically targeting protein-protein interactions: a general platform for an "undruggable" class of disease targets

scientific article

Intracellular expression of anti-p21ras single chain Fv fragments inhibits meiotic maturation of xenopus oocytes.

scientific article published in December 1993

Intracellular immunization: Expression of antibody domains in the cytoplasm and in the nucleus of mammalian cells

scientific article published on 01 January 1991

Intracellular immunization: antibody targeting to subcellular compartments

scientific article published on 01 June 1995

Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice

scientific article

Intranasal delivery of therapeutic proteins for neurological diseases.

scientific article published on 27 May 2011

Intrinsic structural disorder of mouse proNGF.

scientific article published in June 2009

Large differences in aging phenotype between strains of the short-lived annual fish Nothobranchius furzeri

scientific article published on 4 December 2008

Ligand signature in the membrane dynamics of single TrkA receptor molecules.

scientific article published on 25 July 2013

Ligand-induced dynamics of neurotrophin receptors investigated by single-molecule imaging approaches

scientific article

Mismatch between BDNF mRNA and protein expression in the developing visual cortex: the role of visual experience.

scientific article published in February 2001

Molecular simulation of the binding of nerve growth factor peptide mimics to the receptor tyrosine kinase A.

scientific article published on 23 June 2006

Morphological and ultrastructural changes in PC12 pheochromocytoma cells induced by a combined treatment with NGF and taxol

scientific article published on 01 December 1982

NGF and proNGF Reciprocal Interference in Immunoassays: Open Questions, Criticalities, and Ways Forward.

scientific article published on 03 August 2016

Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

scientific article

Nerve growth factor favours long-term depression over long-term potentiation in layer II-III neurones of rat visual cortex.

scientific article published on 8 July 2004

Nerve growth factor regulates axial rotation during early stages of chick embryo development.

scientific article published on 25 January 2012

Neuroantibodies: ectopic expression of a recombinant anti-substance P antibody in the central nervous system of transgenic mice.

scientific article published in August 1995

Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo

scientific article published in March 2005

Neurotrophin and endocannabinoid interactions in the neurobiology of pain

scientific article published on 01 February 2014

Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight.

scientific article

Neutralization of nerve growth factor impairs proliferation and differentiation of adult neural progenitors in the subventricular zone

scientific article published in September 2014

New strategies to address the pharmacodynamics and pharmacokinetics of tumor necrosis factor (TNF) inhibitors: A systematic analysis

scientific article published on 15 May 2015

Nicotine-induced enhancement of synaptic plasticity at CA3-CA1 synapses requires GABAergic interneurons in adult anti-NGF mice.

scientific article

Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease

scientific article published on 13 September 2007

Novel fluorescent cycloheximide derivatives for the imaging of protein synthesis.

scientific article published on 23 April 2010

Nuclear localization of a lactic dehydrogenase with single-stranded DNA-binding properties.

scientific article published in November 1985

Parameter estimate of signal transduction pathways

scientific article

Peripheral neutralization of nerve growth factor induces immunosympathectomy and central neurodegeneration in transgenic mice.

scientific article published in January 2010

Postnatal development of GFAP in mouse visual cortex is not affected by light deprivation.

scientific article published in March 2003

Precursor and mature NGF live tracking: one versus many at a time in the axons

scientific article

Purification, crystallization, X-ray diffraction analysis and phasing of a Fab fragment of monoclonal neuroantibody alphaD11 against nerve growth factor.

scientific article

RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex

scientific article

Reaction mechanism of caspases: insights from QM/MM Car-Parrinello simulations.

scientific article published in August 2003

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

scientific article published on March 2008

Rescue of a neutralizing anti-viral antibody fragment from an intracellular polyclonal repertoire expressed in mammalian cells.

scientific article published on September 1997

Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.

scientific article

Role of nerve growth factor and its receptors in non-nervous cancer growth: efficacy of a tyrosine kinase inhibitor (AG879) and neutralizing antibodies antityrosine kinase receptor A and antinerve growth factor: an in-vitro and in-vivo study

scientific article published on 01 September 2006

Single cycle structure-based humanization of an anti-nerve growth factor therapeutic antibody

scientific article (publication date: 2012)

Single particle tracking of acyl carrier protein (ACP)-tagged TrkA receptors in PC12nnr5 cells.

scientific article

Site-specific labeling of neurotrophins and their receptors via short and versatile peptide tags

scientific article

SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease

scientific journal article

Strategies for identifying genes that play a role in spinal cord regeneration.

scientific article published on January 2004

Structural and functional properties of mouse proNGF.

scientific article

Synthesis and content of a DNA-binding protein with lactic dehydrogenase activity are reduced by nerve growth factor in the neoplastic cell line PC12

TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor

scientific article

TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice

scientific article

TRKB signalling controls the expression of N-methyl-d-aspartate receptors in the visual cortex.

scientific article published in September 2002

Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity

scientific article (publication date: 28 February 2011)

Targeting vectors for intracellular immunisation.

scientific article published on March 1997

Temperature affects longevity and age-related locomotor and cognitive decay in the short-lived fish Nothobranchius furzeri.

scientific article published in June 2006

The conundrum of the high-affinity NGF binding site formation unveiled?

scientific article published on February 2015

The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain

scholarly article

The nerve growth factor. Established findings and controversial aspects.

scientific article published on September 1984

The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis

scientific journal article

The selection of intracellular antibodies.

scientific article

The solution structure of the C-terminal segment of tau protein

scientific article published on 01 November 2000

The use of phage display in neurobiology

scientific article published on 01 June 1995

Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer's disease like pathology

scientific article published on 29 April 2015

Transgenic mice with chronic NGF deprivation and Alzheimer's disease-like pathology display hippocampal region-specific impairments in short- and long-term plasticities.

scientific article published on September 2010

proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces

scientific article

List of works by Antonino Cattaneo

A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.

A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor

A non-radioactive in situ hybridization method that does not require RNAse-free conditions.

A small molecule targeting the multifactorial nature of Alzheimer's disease.

Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE

Activity-dependent expression of Channelrhodopsin at neuronal synapses

Acute cholinergic rescue of synaptic plasticity in the neurodegenerating cortex of anti-nerve-growth-factor mice.

Amyloid plaque-independent deficit of early postnatal visual cortical plasticity in the 5XFAD transgenic model of Alzheimer's disease

Annual fishes of the genus Nothobranchius as a model system for aging research

Assembled IgG molecules are exported from the endoplasmic reticulum in myeloma cells despite the retention signal SEKDEL.

Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies

Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis.

Cloning and expression of an anti-nerve growth factor (NGF) antibody for studies using the neuroantibody approach.

Co-expression of TrkB and the N-methyl-D-aspartate receptor subunits NR1-C1, NR2A and NR2B in the rat visual cortex.

Conformational plasticity of proNGF

Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum.

Contrast influence on perceived orientation

Corrigendum: Precursor and mature NGF live tracking: one versus many at a time in the axons.

Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice.

Design and selection of an intrabody library produced de-novo for the non-structural protein NSP5 of rotavirus.

Development of a non invasive NGF-based therapy for Alzheimer's disease.

Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers

Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment

Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody

Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation.

Early inflammation and immune response mRNAs in the brain of AD11 anti-NGF mice.

Effects of intrabodies specific for rotavirus NSP5 during the virus replicative cycle.

Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer-collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice.

Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications

Gene expression biomarkers in the brain of a mouse model for Alzheimer's disease: mining of microarray data by logic classification and feature selection

Gene expression changes in the motor cortex mediating motor skill learning

Gephyrin selective intrabodies as a new strategy for studying inhibitory receptor clustering.

IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models.

Immunosympathectomy as the first phenotypic knockout with antibodies.

In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction

In vitro receptor binding properties of a "painless" NGF mutein, linked to hereditary sensory autonomic neuropathy type V.

In vivo selection of intrabodies specifically targeting protein-protein interactions: a general platform for an "undruggable" class of disease targets

Intracellular expression of anti-p21ras single chain Fv fragments inhibits meiotic maturation of xenopus oocytes.

Intracellular immunization: Expression of antibody domains in the cytoplasm and in the nucleus of mammalian cells

Intracellular immunization: antibody targeting to subcellular compartments

Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice

Intranasal delivery of therapeutic proteins for neurological diseases.

Intrinsic structural disorder of mouse proNGF.

Large differences in aging phenotype between strains of the short-lived annual fish Nothobranchius furzeri

Ligand signature in the membrane dynamics of single TrkA receptor molecules.

Ligand-induced dynamics of neurotrophin receptors investigated by single-molecule imaging approaches

Mismatch between BDNF mRNA and protein expression in the developing visual cortex: the role of visual experience.

Molecular simulation of the binding of nerve growth factor peptide mimics to the receptor tyrosine kinase A.

Morphological and ultrastructural changes in PC12 pheochromocytoma cells induced by a combined treatment with NGF and taxol

NGF and proNGF Reciprocal Interference in Immunoassays: Open Questions, Criticalities, and Ways Forward.

Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

Nerve growth factor favours long-term depression over long-term potentiation in layer II-III neurones of rat visual cortex.

Nerve growth factor regulates axial rotation during early stages of chick embryo development.

Neuroantibodies: ectopic expression of a recombinant anti-substance P antibody in the central nervous system of transgenic mice.

Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo

Neurotrophin and endocannabinoid interactions in the neurobiology of pain

Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight.

Neutralization of nerve growth factor impairs proliferation and differentiation of adult neural progenitors in the subventricular zone

New strategies to address the pharmacodynamics and pharmacokinetics of tumor necrosis factor (TNF) inhibitors: A systematic analysis

Nicotine-induced enhancement of synaptic plasticity at CA3-CA1 synapses requires GABAergic interneurons in adult anti-NGF mice.

Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease

Novel fluorescent cycloheximide derivatives for the imaging of protein synthesis.

Nuclear localization of a lactic dehydrogenase with single-stranded DNA-binding properties.

Parameter estimate of signal transduction pathways

Peripheral neutralization of nerve growth factor induces immunosympathectomy and central neurodegeneration in transgenic mice.

Postnatal development of GFAP in mouse visual cortex is not affected by light deprivation.

Precursor and mature NGF live tracking: one versus many at a time in the axons

Purification, crystallization, X-ray diffraction analysis and phasing of a Fab fragment of monoclonal neuroantibody alphaD11 against nerve growth factor.

RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex

Reaction mechanism of caspases: insights from QM/MM Car-Parrinello simulations.

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

Rescue of a neutralizing anti-viral antibody fragment from an intracellular polyclonal repertoire expressed in mammalian cells.

Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.

Role of nerve growth factor and its receptors in non-nervous cancer growth: efficacy of a tyrosine kinase inhibitor (AG879) and neutralizing antibodies antityrosine kinase receptor A and antinerve growth factor: an in-vitro and in-vivo study

Single cycle structure-based humanization of an anti-nerve growth factor therapeutic antibody

Single particle tracking of acyl carrier protein (ACP)-tagged TrkA receptors in PC12nnr5 cells.

Site-specific labeling of neurotrophins and their receptors via short and versatile peptide tags

SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease