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List of works by Darren R Feldman

A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma

scientific article published on 10 June 2016

A phase 2 multicenter study of tivantinib (ARQ 197) monotherapy in patients with relapsed or refractory germ cell tumors.

scientific article published on 17 February 2013

A review of second-line chemotherapy and prognostic models for disseminated germ cell tumors.

scientific article published on 22 April 2011

Are Some Cases of Somatic Type Malignancy Potentially Avoidable?

scientific article published on 13 April 2016

Bevacizumab Monotherapy as Salvage Therapy for Advanced Clear Cell Renal Cell Carcinoma Pretreated With Targeted Drugs.

scientific article published on 07 August 2015

Beyond stage I germ cell tumors: current status regarding treatment and long-term toxicities.

scientific article published on January 2014

Bilateral Testicular Germ Cell Tumors in the Era of Multimodal Therapy

scientific article published on 2 November 2016

Body Mass Index Is Associated With Higher Lymph Node Counts During Retroperitoneal Lymph Node Dissection ⬇️

scientific article published on December 14, 2011

Brain Metastases in Patients With Germ Cell Tumors: Prognostic Factors and Treatment Options--An Analysis From the Global Germ Cell Cancer Group

scientific article published on 12 October 2015

Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial.

scientific article

Cabozantinib versus sunitinib as initial therapy for metastatic renal cell carcinoma of intermediate or poor risk (Alliance A031203 CABOSUN randomised trial): Progression-free survival by independent review and overall survival update.

scientific article published on 15 March 2018

Characterization and Impact of TERT Promoter Region Mutations on Clinical Outcome in Renal Cell Carcinoma.

scientific article published on 23 September 2017

Characterizing recurrent and lethal small renal masses in clear cell renal cell carcinoma using recurrent somatic mutations.

scientific article published on 10 November 2017

Cisplatin Therapy Does Not Worsen Renal Function in Severe Antenatal Bartter Syndrome

scientific article published on 8 May 2017

Clinical Outcome of Patients with Fibrosis/Necrosis at Post-Chemotherapy Retroperitoneal Lymph Node Dissection for Advanced Germ Cell Tumors

scientific article

Clinical Outcome of Retroperitoneal Lymph Node Dissection after Chemotherapy in Patients with Pure Embryonal Carcinoma in the Orchiectomy Specimen.

scientific article published in February 2018

Clinical Outcomes of Local and Metastatic Testicular Sex Cord-Stromal Tumors

scientific article published on 08 February 2014

Clinical and Genetic Risk Factors for Adverse Metabolic Outcomes in North American Testicular Cancer Survivors.

scientific article published in March 2018

Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer

scientific article published on 13 June 2017

Clinical and Genome-Wide Analysis of Multiple Severe Cisplatin-Induced Neurotoxicities in Adult-Onset Cancer Survivors

scientific article published on 30 September 2020

Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy

scientific article published on 11 July 2019

Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors.

scientific article

Clinical impact of residual extraretroperitoneal masses in patients with advanced nonseminomatous germ cell testicular cancer

scientific article published in January 2012

Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma

scientific article published on 20 October 2017

Contemporary lymph node counts during primary retroperitoneal lymph node dissection.

scientific article

Controversies in the Management of Clinical Stage I Seminoma: Carboplatin a Decade in-Time to Start Backing Out.

scientific article published in February 2018

Conventional-Dose versus High-Dose Chemotherapy for Relapsed Germ Cell Tumors.

scientific article published on 15 March 2018

Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study

scientific article published on 4 April 2018

Curing germ cell tumors after failure of high-dose chemotherapy: progress through clinical trials

scientific article published on 17 July 2007

Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach

scientific article published in December 2015

Development of a risk stratification system to guide treatment for female germ cell tumors.

scientific article published on 23 June 2015

Editorial comment

Evaluation of lymph node counts in primary retroperitoneal lymph node dissection.

scientific article

Everolimus plus bevacizumab is an effective first-line treatment for patients with advanced papillary variant renal cell carcinoma: Final results from a phase II trial

scientific article published on 25 September 2020

Fertility preservation strategies for male patients with cancer ⬇️

scientific article published on 09 July 2013

Follow-Up Management of Patients With Testicular Cancer: A Multidisciplinary Consensus-Based Approach.

scientific article published on June 2015

Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors

scientific article

Genomic Characterization of Renal Medullary Carcinoma and Treatment Outcomes

scientific article published on 26 April 2017

Genomic alterations as predictors of survival among patients within a combined cohort with clear cell renal cell carcinoma undergoing cytoreductive nephrectomy

scientific article published on 10 April 2017

Good-risk-advanced germ cell tumors: historical perspective and current standards of care.

scientific article published on 10 June 2009

Hearing Loss in Adult Survivors of Childhood Cancer Treated with Radiotherapy.

scientific article published on 4 May 2018

High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab

publication published on 26 May 2021

High incidence of thromboembolic events in patients treated with cisplatin-based chemotherapy: a large retrospective analysis

scientific article published on 01 August 2011

High-dose chemotherapy and stem cell transplantation for advanced testicular cancer

scientific article published on July 2011

Histologic and Oncologic Outcomes Following Liver Mass Resection With Retroperitoneal Lymph Node Dissection in Patients With Nonseminomatous Germ Cell Tumor

scientific article published on 25 April 2018

Infectious complications from high-dose chemotherapy and autologous stem cell transplantation for metastatic germ cell tumors

scientific article published in May 2008

Integrated Molecular Characterization of Testicular Germ Cell Tumors

article by Hui Shen et al published 12 June 2018 in Cell Reports

Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma

scientific article

Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency

scientific article

Is High Dose Therapy Superior to Conventional Dose Therapy as Initial Treatment for Relapsed Germ Cell Tumors? The TIGER Trial ⬇️

scientific article published on January 1, 2011

Is high-dose chemotherapy effective in patients with relapsed or refractory germ cell tumors?

scientific article published on 11 December 2007

Late Relapse of Testicular Germ Cell Tumors

scientific article published on 16 June 2015

Late cardiovascular toxicity following chemotherapy for germ cell tumors.

scientific article published on April 2012

Long-Term Response to Sunitinib Therapy for Metastatic Renal Cell Carcinoma ⬇️

scientific article published on May 24, 2013

Long-term mortality in patients with germ cell tumors: effect of primary cancer site on cause of death.

scientific article

Medical treatment of advanced testicular cancer.

scientific article

Microwave ablation (MWA) for the treatment of a solitary, chemorefractory testicular cancer liver metastasis

scientific article

Multi-Institutional Assessment of Adverse Health Outcomes Among North American Testicular Cancer Survivors After Modern Cisplatin-Based Chemotherapy.

scientific article

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

scientific article published on 8 May 2017

Outcomes After Resection of Postchemotherapy Residual Neck Mass in Patients With Germ Cell Tumors—An Update

scientific article published on 01 March 2011

Outcomes in patients with clinical stage III NSGCT who achieve complete clinical response to chemotherapy at extraretroperitoneal disease site.

scientific article published on 23 March 2012

Paclitaxel, Ifosfamide, and Cisplatin Efficacy for First-Line Treatment of Patients With Intermediate- or Poor-Risk Germ Cell Tumors

scientific article published on 16 May 2016

Paclitaxel, ifosfamide and cisplatin (TIP) beyond its original indication for salvage treatment of germ cell tumors

scientific article published on 23 August 2011

Patient-Reported Functional Impairment Due to Hearing Loss and Tinnitus After Cisplatin-Based Chemotherapy

scientific article published in 2023

Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration

scientific article

Pelvic Lymph Node Dissection in Patients Treated for Testis Cancer: The Memorial Sloan Kettering Cancer Center Experience

scientific article published on 25 May 2016

Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers

scientific article published on 25 October 2016

Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma ⬇️

scientific article published on September 6, 2011

Phase I study of flavopiridol with oxaliplatin and fluorouracil/leucovorin in advanced solid tumors

scientific article

Phase I trial of bevacizumab plus escalated doses of sunitinib in patients with metastatic renal cell carcinoma.

scientific article published on 17 February 2009

Phase I/II Trial of Paclitaxel With Ifosfamide Followed by High-Dose Paclitaxel, Ifosfamide, and Carboplatin (TI-TIC) With Autologous Stem Cell Reinfusion for Salvage Treatment of Germ Cell Tumors.

scientific article published on 16 May 2015

Phase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma.

scientific article published on 6 September 2016

Phase II Trial of ixabepilone in patients with cisplatin-refractory germ cell tumors

scientific article published on 23 May 2007

Phase II trial of sunitinib in patients with relapsed or refractory germ cell tumors.

scientific article published on 23 June 2009

Practice Makes Perfect: The Rest of the Story in Testicular Cancer as a Model Curable Neoplasm

scientific article published on 30 August 2017

Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors.

scientific article published on 8 May 2014

Progression-free and overall survival in patients with relapsed/refractory germ cell tumors treated with single-agent chemotherapy: endpoints for clinical trial design.

scientific article published on 26 July 2011

Quality-adjusted survival with first-line cabozantinib or sunitinib for advanced renal cell carcinoma in the CABOSUN randomized clinical trial (Alliance)

scientific article published on 06 October 2020

Rare de novo germline copy-number variation in testicular cancer

scientific article published on 2 August 2012

Rates of teratoma and viable cancer at post-chemotherapy retroperitoneal lymph node dissection after induction chemotherapy for good risk nonseminomatous germ cell tumors.

scientific article

Re: Hypothyroidism in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib

scientific article published on 12 June 2007

Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition

scientific article

Relationship of Cisplatin-Related Adverse Health Outcomes With Disability and Unemployment Among Testicular Cancer Survivors

scientific article published on 20 March 2020

Reply to L.C. Pagliaro et al

scientific article published on 01 June 2015

Response to Nivolumab in a Patient With Metastatic Clear Cell Renal Cell Carcinoma and End-stage Renal Disease on Dialysis

scientific article published on 13 June 2016

Revisiting DNA damage repair, p53-mediated apoptosis and cisplatin sensitivity in germ cell tumors.

scientific article published on January 2013

Risk of Vascular Toxicity with Platinum Based Chemotherapy in Elderly Patients with Bladder Cancer

scientific article published on 01 September 2015

Salvage high-dose chemotherapy for germ cell tumors.

scientific article published on 30 March 2015

Sarcomatoid-variant renal cell carcinoma: treatment outcome and survival in advanced disease.

scientific article published on October 2011

Solid and Hematologic Neoplasms After Testicular Cancer: A US Population-Based Study of 24 900 Survivors

scientific article published on 17 March 2020

Sunitinib in metastatic renal cell carcinoma: recommendations for management of noncardiovascular toxicities.

scientific article published on 13 April 2011

Testicular cancer survivorship: research strategies and recommendations

scientific article

The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma

scientific article published on 10 May 2018

The conundrum of clinical trials in adult germ-cell tumours ⬇️

scientific article published on January 1, 2013

The risk of hand foot skin reaction to pazopanib, a novel multikinase inhibitor: a systematic review of literature and meta-analysis.

scientific article published on 11 March 2011

The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: A systematic review of the literature and meta-analysis ⬇️

scientific article published on December 27, 2011

The role of high-dose chemotherapy in the management of germ cell tumors.

scientific article published on May 2014

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases.

scientific article

Treatment of stage I seminoma: is it time to change your practice?

scientific article published on 7 November 2008

Treatment options for stage I nonseminoma

scientific article

Treatment outcome with mTOR inhibitors for metastatic renal cell carcinoma with nonclear and sarcomatoid histologies.

scientific article

Tumor Xenografts of Human Clear Cell Renal Cell Carcinoma But Not Corresponding Cell Lines Recapitulate Clinical Response to Sunitinib: Feasibility of Using Biopsy Samples

scientific article published on 25 August 2016

Update in germ cell tumours.

scientific article published on May 2015

Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity

scientific article published on 30 December 2016

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