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List of works by Yoon-Sim Yap

1Phase I trial of expanded, activated autologous NK cell infusions with trastuzumab in patients with HER2-positive cancers

scientific article published on 10 June 2020

A phase II study of weekly docetaxel in patients with anthracycline pretreated metastatic breast cancer

scientific article

A preliminary study for the assessment of PD-L1 and PD-L2 on circulating tumor cells by microfluidic-based chipcytometry

scientific article published on 4 September 2017

Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines

scientific article published on 01 June 2006

Assessment of PARP4 as a candidate breast cancer susceptibility gene

scientific article published on 22 May 2019

Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients.

scientific article published on 22 January 2016

Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.

scientific article published on 11 September 2012

Association of proinflammatory cytokines and chemotherapy-associated cognitive impairment in breast cancer patients: a multi-centered, prospective, cohort study

scientific article published on 28 April 2015

BioPATH: A Biomarker Study in Asian Patients with HER2+ Advanced Breast Cancer Treated with Lapatinib and Other Anti-HER2 Therapy

scientific article published on 04 June 2019

Brain metastases in Asian HER2-positive breast cancer patients: anti-HER2 treatments and their impact on survival ⬇️

scientific article published on August 23, 2012

Brain-derived neurotrophic factor genetic polymorphism (rs6265) is protective against chemotherapy-associated cognitive impairment in patients with early-stage breast cancer

scientific article

Breast cancer in women with neurofibromatosis type 1 (NF1): a comprehensive case series with molecular insights into its aggressive phenotype

scientific article published on 21 June 2018

Breast cancer risk in neurofibromatosis type 1 is a function of the type of NF1 gene mutation: a new genotype-phenotype correlation

article

Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence.

scientific article

Clinical efficacy of capecitabine as first-line chemotherapy in metastatic breast cancer--how low can you go?

scientific article published on 26 March 2007

Comparison of the measurement properties between a short and generic instrument, the 5-level EuroQoL Group's 5-dimension (EQ-5D-5L) questionnaire, and a longer and disease-specific instrument, the Functional Assessment of Cancer Therapy-Breast (FACT

scientific article published on 11 October 2012

Contrasting Epidemiology and Clinicopathology of Female Breast Cancer in Asians vs the US Population

scientific article published on 01 December 2019

Detection and prognostic relevance of circulating tumour cells (CTCs) in Asian breast cancers using a label-free microfluidic platform

scientific article published on 25 September 2019

Distinct and heterogeneous trajectories of self-perceived cognitive impairment among Asian breast cancer survivors

scientific article published on 9 January 2018

Effects of chemotherapy and psychosocial distress on perceived cognitive disturbances in Asian breast cancer patients.

scientific article published on 18 December 2012

Elucidating therapeutic molecular targets in premenopausal Asian women with recurrent breast cancers

scientific article published on 26 July 2018

Evaluation of nanofluidics technology for high-throughput SNP genotyping in a clinical setting

scientific article

Evaluation of three polygenic risk score models for the prediction of breast cancer risk in Singapore Chinese.

scientific article

Everolimus for women with trastuzumab-resistant, HER2-positive, advanced breast cancer (BOLERO-3): a randomised, double-blind, placebo-controlled phase 3 trial

scientific article published on 14 April 2014

Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

scientific article published on 06 October 2021

Genotype-Phenotype Correlation in NF1: Evidence for a More Severe Phenotype Associated with Missense Mutations Affecting NF1 Codons 844-848.

scientific article published on 21 December 2017

Identification of Novel Breast Cancer Risk Loci.

scientific article published on 03 August 2017

Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients

scientific article

Inherited breast cancer predisposition in Asians: multigene panel testing outcomes from Singapore.

scientific article published on 13 January 2016

Insights Into Breast Cancer in the East vs the West: A Review

scientific article published on 16 May 2019

Low-dose anti-inflammatory combinatorial therapy reduced cancer stem cell formation in patient-derived preclinical models for tumour relapse prevention

scientific article published on 04 February 2019

Lymphomatous infiltration of the peripheral nervous system in enteropathy-associated T-cell lymphoma

scientific article published on 01 April 2005

Measurement properties of the English and Chinese versions of the Functional Assessment of Cancer Therapy-Breast (FACT-B) in Asian breast cancer patients.

scientific article published on 16 September 2011

Measurement properties of the eight-item abbreviated functional assessment of cancer therapy--breast symptom index and comparison with its 37-item parent measure.

scientific article

Minimal clinically important difference (MCID) for the functional assessment of cancer therapy: cognitive function (FACT-Cog) in breast cancer patients.

scientific article published on 18 March 2014

Neratinib after trastuzumab-based adjuvant therapy in patients from Asia with early stage HER2-positive breast cancer

scientific article published on 29 May 2019

Outcome after neoadjuvant chemotherapy in Asian breast cancer patients ⬇️

scientific article published on 20 December 2016

PI3K/Akt/mTOR inhibitors in breast cancer

scientific article

Patient Management with Eribulin in Metastatic Breast Cancer: A Clinical Practice Guide

scientific article

Patterns of relapse after neoadjuvant chemotherapy in breast cancer: implications for surveillance in clinical practice

scientific article published on 30 May 2019

Predictive Factors for BRCA1 and BRCA2 Genetic Testing in an Asian Clinic-Based Population.

scientific article published on 29 July 2015

Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial.

scientific article

Reducing the risk of peripherally inserted central catheter line complications in the oncology setting.

scientific article published on September 2006

Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy

scientific article published on 31 October 2018

Response to Sung, Rosenberg, and Yang

scientific article published on 23 September 2019

Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer.

scientific article published on 7 October 2016

The English and Chinese versions of the five-level EuroQoL Group's five-dimension questionnaire (EQ-5D) were valid and reliable and provided comparable scores in Asian breast cancer patients ⬇️

scientific article published on June 6, 2012

Treating HR+/HER2- breast cancer in premenopausal Asian women: Asian Breast Cancer Cooperative Group 2019 Consensus and position on ovarian suppression

scientific article published on 04 July 2019

Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer

scientific article published on 01 November 2019

Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer.

scientific article

Validation of a Risk Score Incorporating Tumor Characteristics into the American Joint Committee on Cancer Anatomic Stage for Breast Cancer

scientific article published on 27 March 2019

Validation of the AJCC 8th prognostic system for breast cancer in an Asian healthcare setting

scientific article published on 17 April 2018

Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1.

scientific article published on 03 October 2015

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