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List of works by Iain R Macpherson

A phase 1 study of OSI-930 in combination with erlotinib in patients with advanced solid tumours.

scientific article published on 22 October 2012

A proteomic approach to identify endosomal cargoes controlling cancer invasiveness.

scientific article published on 6 January 2017

A randomised trial of the cool pad pillow topper versus standard care for sleep disturbance and hot flushes in women on endocrine therapy for breast cancer.

scientific article

A randomised, open-label phase II trial of afatinib versus cetuximab in patients with metastatic colorectal cancer

scientific article published on 28 October 2014

Adjuvant treatment of breast cancer in postmenopausal women: role of exemestane.

scientific article published on 14 October 2010

Auto-immune neutropenia occurring in association with malignant melanoma

scientific article published on 01 January 2003

CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer

scientific article

Comparing Breast Cancer Multiparameter Tests in the OPTIMA Prelim Trial: No Test Is More Equal Than the Others

scientific article published on 29 April 2016

Current status of cediranib: the rapid development of a novel anti-angiogenic therapy.

scientific article published on May 2009

FAK acts as a suppressor of RTK-MAP kinase signalling in Drosophila melanogaster epithelia and human cancer cells

scientific article (publication date: March 2014)

Genomic profile of advanced breast cancer in circulating tumour DNA

scientific article published on 23 April 2021

Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells.

scientific article published on 21 December 2017

Loading dose ibandronate versus standard oral ibandronate in patients with bone metastases from breast cancer

scientific article published on 02 October 2014

Long-term Follow-up Data from Pivotal Studies of Adjuvant Trastuzumab in Early Breast Cancer.

scientific article

Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels ⬇️

scientific article published in Nature Communications

N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods

scientific article

Neoadjuvant Therapy in Early Breast Cancer: Treatment Considerations and Common Debates in Practice

scientific article published on 29 June 2017

Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer

scientific article published on 21 August 2015

New approaches in the management of advanced breast cancer - role of combination treatment with liposomal doxorubicin

scientific article published on 31 August 2009

Performance of formulae based estimates of glomerular filtration rate for carboplatin dosing in stage 1 seminoma

scientific article published on 17 January 2014

Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses ⬇️

scientific article published on November 21, 2012

Practicalities of using an adaptive design for decision making within the optima trial: optimal personalized treatment of early breast cancer using multi-parameter tests.

scientific article published on 16 November 2015

Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression.

scientific article

Regorafenib plus modified FOLFOX6 as first-line treatment of metastatic colorectal cancer: A phase II trial.

scientific article published on 25 March 2015

Response to: ‘Letter to the editor, European Journal of Cancer’, commenting on ‘Performance of formulae based estimates of glomerular filtration rate for carboplatin dosing in stage 1 seminoma’

article

Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer

scientific article published on 10 June 2022

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.

scientific article published on 15 February 2017

Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA).

scientific article

The presentation, management and outcome of inflammatory breast cancer cases in the UK: Data from a multi-centre retrospective review

scientific article published on 15 September 2018

Triplet therapy with palbociclib, taselisib and fulvestrant in PIK3CA mutant breast cancer and doublet palbociclib and taselisib in pathway mutant solid cancers

scientific article published on 21 September 2020

Value of Information Analysis of Multiparameter Tests for Chemotherapy in Early Breast Cancer: The OPTIMA Prelim Trial ⬇️

scientific article published on 11 July 2017

p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism.

scientific article

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