List of works - Alexandre Benmerah

A JC virus-induced signal is required for infection of glial cells by a clathrin- and eps15-dependent pathway

scientific article

AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis

scientific article

AP-2/Eps15 interaction is required for receptor-mediated endocytosis

scientific article

Agonists of prostaglandin E<sub>2</sub> receptors as potential first in class treatment for nephronophthisis and related ciliopathies

scientific article published on 28 April 2022

Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis

scientific article

Antigen stored in dendritic cells after macropinocytosis is released unprocessed from late endosomes to target B cells

scientific article published on 02 November 2011

Arl13b and the exocyst interact synergistically in ciliogenesis

scientific article

C-terminal oligomerization of podocin mediates interallelic interactions

scientific article published on 13 April 2018

Cilia in hereditary cerebral anomalies

scientific article published on 17 June 2019

Ciliary kinesins beyond IFT: Cilium length, disassembly, cargo transport and signalling

scientific article published on 15 February 2019

Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development.

scientific article

Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome

scientific article published in July 2008

Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.

scientific article published on 6 August 2002

Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R.

scientific article

Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins.

scientific article published on 3 June 2011

Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane

scientific article published on 28 November 2006

Dynamics of clathrin and adaptor proteins during endocytosis

scientific article published in November 2006

Endocytosis and toxicity of clostridial binary toxins depend on a clathrin-independent pathway regulated by Rho-GDI

scientific article published on 19 October 2010

Endocytosis: signaling from endocytic membranes to the nucleus.

scientific article published on April 2004

Eps15 and Epsin1 are crucial for enteropathogenic Escherichia coli pedestal formation despite the absence of adaptor protein 2.

scientific article published on 2 August 2011

Food allergens are protected from degradation during CD23-mediated transepithelial transport.

scientific article published on 2 September 2004

Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies.

scientific article

Homo- and hetero-oligomerization of beta-arrestins in living cells

scientific article

Homotypic aggregation of CD103 (alpha E beta 7)+ lymphocytes by an anti-CD103 antibody, HML-4.

scientific article published on September 1994

Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments

scientific article published on 18 March 2010

Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans

scientific article

Intestinal epithelial CD23 mediates enhanced antigen transport in allergy: evidence for novel splice forms.

scientific article published on 13 March 2003

Intracellular trafficking of CD23: differential regulation in humans and mice by both extracellular and intracellular exons.

scientific article

Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction

scientific article published on 23 August 2014

Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish

scientific article published on 01 March 2019

Lysosomal Targeting of Cystinosin Requires AP-3.

scientific article published on 24 March 2015

Mapping of Eps15 domains involved in its targeting to clathrin-coated pits.

scientific article published in February 2000

Monitoring β-Arrestin 2 Targeting to the Centrosome, Basal Body, and Primary Cilium by Fluorescence Microscopy

scientific article published on 01 January 2019

Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy.

scientific article published in January 2016

Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis

scientific article

Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization

scientific journal article

Mutations of CEP83 cause infantile nephronophthisis and intellectual disability

scientific article

Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase

scientific article

Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity

scientific article

Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation

scientific article

Nuclear functions for plasma membrane-associated proteins?

scientific article

Plasma membrane targeting of podocin through the classical exocytic pathway: effect of NPHS2 mutations

scientific article published on January 2004

Quiescent melanocytes form primary cilia

scientific article published on 01 June 2014

Rab4b controls an early endosome sorting event by interacting with the γ-subunit of the clathrin adaptor complex 1.

scientific article published on 4 September 2013

Recruitment of activated G protein-coupled receptors to pre-existing clathrin-coated pits in living cells

scientific article published on 15 October 2001

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length

scientific journal article

Studies on endocytic mechanisms of the Menkes copper-translocating P-type ATPase (ATP7A; MNK). Endocytosis of the Menkes protein.

scientific article published in February 2004

TGF-β signaling is associated with endocytosis at the pocket region of the primary cilium

scientific article published on 6 June 2013

Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control

scientific journal article

The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport.

scientific article

The AP-2 Complex Is Excluded from the Dynamic Population of Plasma Membrane-associated Clathrin

scientific article published on 6 October 2003

The Conserved Isoleucine-Valine-Phenylalanine Motif Couples Activation State and Endocytic Functions of β-Arrestins

scientific article published on 4 June 2007

The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway

scientific article (publication date: 2003)

The NF-κB signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles

scientific article

The ciliary pocket.

scientific article

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

scientific article published on March 2011

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

scientific journal article

The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein

scientific article

The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

scientific article

Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction

scientific article

Understanding Living Clathrin-Coated Pits

scientific article published in May 2004

Understanding living clathrin-coated pits.

scientific article published on May 2004

[G protein coupled receptor endocytosis]

scientific article published on 01 January 2004

[The ciliary pocket: a rendezvous between the centrosome and vesicular trafficking]

scientific article published on 10 November 2014

beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53.

scholarly article

αTAT1 catalyses microtubule acetylation at clathrin-coated pits

scientific article

List of works by Alexandre Benmerah

A JC virus-induced signal is required for infection of glial cells by a clathrin- and eps15-dependent pathway

AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis

AP-2/Eps15 interaction is required for receptor-mediated endocytosis

Agonists of prostaglandin E<sub>2</sub> receptors as potential first in class treatment for nephronophthisis and related ciliopathies

Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis

Antigen stored in dendritic cells after macropinocytosis is released unprocessed from late endosomes to target B cells

Arl13b and the exocyst interact synergistically in ciliogenesis

C-terminal oligomerization of podocin mediates interallelic interactions

Cilia in hereditary cerebral anomalies

Ciliary kinesins beyond IFT: Cilium length, disassembly, cargo transport and signalling

Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development.

Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome

Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.

Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R.

Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins.

Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane

Dynamics of clathrin and adaptor proteins during endocytosis

Endocytosis and toxicity of clostridial binary toxins depend on a clathrin-independent pathway regulated by Rho-GDI

Endocytosis: signaling from endocytic membranes to the nucleus.

Eps15 and Epsin1 are crucial for enteropathogenic Escherichia coli pedestal formation despite the absence of adaptor protein 2.

Food allergens are protected from degradation during CD23-mediated transepithelial transport.

Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies.

Homo- and hetero-oligomerization of beta-arrestins in living cells

Homotypic aggregation of CD103 (alpha E beta 7)+ lymphocytes by an anti-CD103 antibody, HML-4.

Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments

Integrin alpha 8 recessive mutations are responsible for bilateral renal agenesis in humans

Intestinal epithelial CD23 mediates enhanced antigen transport in allergy: evidence for novel splice forms.

Intracellular trafficking of CD23: differential regulation in humans and mice by both extracellular and intracellular exons.

Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction

Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish

Lysosomal Targeting of Cystinosin Requires AP-3.

Mapping of Eps15 domains involved in its targeting to clathrin-coated pits.

Monitoring β-Arrestin 2 Targeting to the Centrosome, Basal Body, and Primary Cilium by Fluorescence Microscopy

Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy.

Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis

Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization

Mutations of CEP83 cause infantile nephronophthisis and intellectual disability

Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase

Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity

Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation

Nuclear functions for plasma membrane-associated proteins?

Plasma membrane targeting of podocin through the classical exocytic pathway: effect of NPHS2 mutations

Quiescent melanocytes form primary cilia

Rab4b controls an early endosome sorting event by interacting with the γ-subunit of the clathrin adaptor complex 1.

Recruitment of activated G protein-coupled receptors to pre-existing clathrin-coated pits in living cells

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length

Studies on endocytic mechanisms of the Menkes copper-translocating P-type ATPase (ATP7A; MNK). Endocytosis of the Menkes protein.

TGF-β signaling is associated with endocytosis at the pocket region of the primary cilium

Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control

The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport.

The AP-2 Complex Is Excluded from the Dynamic Population of Plasma Membrane-associated Clathrin

The Conserved Isoleucine-Valine-Phenylalanine Motif Couples Activation State and Endocytic Functions of β-Arrestins

The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway

The NF-κB signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles

The ciliary pocket.

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein

The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction

Understanding Living Clathrin-Coated Pits

Understanding living clathrin-coated pits.

[G protein coupled receptor endocytosis]

[The ciliary pocket: a rendezvous between the centrosome and vesicular trafficking]

beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53.

αTAT1 catalyses microtubule acetylation at clathrin-coated pits

γ-Adaptin Appendage Domain