List of works - Matthias Gehringer

2-(3-{(3R,4R)-4-Methyl-3-[meth-yl(7H-pyrrolo-[2,3-d]pyrimidin-4-yl)amino]-piperidin-1-yl}oxetan-3-yl)aceto-nitrile monohydrate.

scientific article published on 5 March 2014

Click Chemistry: Novel Applications in Cell Biology and Drug Discovery.

scientific article published on 25 October 2017

Configurationally Stabilized Analogs of M. ulcerans Exotoxins Mycolactones A and B Reveal the Importance of Side Chain Geometry for Mycolactone Virulence

scientific article published on 11 July 2019

Covalent inhibitors: back on track?

scientific article published on 29 June 2020

Design and synthesis of tricyclic JAK3 inhibitors with picomolar affinities as novel molecular probes

scientific article published on 8 January 2014

Developing Small-Molecule Inhibitors of HECT-Type Ubiquitin Ligases for Therapeutic Applications: Challenges and Opportunities

scientific article published on 17 October 2018

Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold

scientific article published on 13 June 2018

Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK

scientific article published on 04 December 2020

Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology

scientific article published on 25 January 2019

Inhibitors of c-Jun N-terminal kinases: an update.

scientific article

New insights into novel inhibitors against deoxyhypusine hydroxylase from plasmodium falciparum: compounds with an iron chelating potential

scientific article published on 26 February 2015

Novel hinge-binding motifs for Janus kinase 3 inhibitors: a comprehensive structure-activity relationship study on tofacitinib bioisosteres.

scientific article

Recent advances in JAK3 inhibition: Isoform selectivity by covalent cysteine targeting

scientific article published on 29 July 2017

Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

scientific article published on 7 November 2016

Solution-phase parallel synthesis of ruxolitinib-derived Janus kinase inhibitors via copper-catalyzed azide-alkyne cycloaddition.

scientific article

The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR.

scientific article

The chemistry and biology of mycolactones.

scientific article published on 11 August 2017

Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1).

scientific article

c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).

scientific article published on 19 May 2015

tert-Butyl N-[(3R,4R)-1-(2-cyano-acet-yl)-4-methyl-piperidin-3-yl]-N-methyl-carbamate.

scientific article published on 22 May 2013

List of works by Matthias Gehringer

2-(3-{(3R,4R)-4-Methyl-3-[meth-yl(7H-pyrrolo-[2,3-d]pyrimidin-4-yl)amino]-piperidin-1-yl}oxetan-3-yl)aceto-nitrile monohydrate.

Click Chemistry: Novel Applications in Cell Biology and Drug Discovery.

Configurationally Stabilized Analogs of M. ulcerans Exotoxins Mycolactones A and B Reveal the Importance of Side Chain Geometry for Mycolactone Virulence

Covalent inhibitors: back on track?

Design and synthesis of tricyclic JAK3 inhibitors with picomolar affinities as novel molecular probes

Developing Small-Molecule Inhibitors of HECT-Type Ubiquitin Ligases for Therapeutic Applications: Challenges and Opportunities

Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold

Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK

Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology

Inhibitors of c-Jun N-terminal kinases: an update.

New insights into novel inhibitors against deoxyhypusine hydroxylase from plasmodium falciparum: compounds with an iron chelating potential

Novel hinge-binding motifs for Janus kinase 3 inhibitors: a comprehensive structure-activity relationship study on tofacitinib bioisosteres.

Recent advances in JAK3 inhibition: Isoform selectivity by covalent cysteine targeting

Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Solution-phase parallel synthesis of ruxolitinib-derived Janus kinase inhibitors via copper-catalyzed azide-alkyne cycloaddition.

The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR.

The chemistry and biology of mycolactones.

Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1).

c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).

tert-Butyl N-[(3R,4R)-1-(2-cyano-acet-yl)-4-methyl-piperidin-3-yl]-N-methyl-carbamate.