List of works - Thomas Litman

A Serial Analysis of Gene Expression (SAGE) database analysis of chemosensitivity: comparing solid tumors with cell lines and comparing solid tumors from different tissue origins.

scientific article

A database study that identifies genes whose expression correlates, negatively or positively, with 5-year survival of cancer patients

scientific article published on 25 January 2007

ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines

scientific article published on 01 August 1997

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

scientific article

Adrenocortical Cancer: A Molecularly Complex Disease Where Surgery Matters

scientific article published on October 2016

Ammonia and urea permeability of mammalian aquaporins.

scientific article published on January 2009

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma

scientific article published on 22 July 2019

C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin

scientific article published on 22 February 2022

Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

scientific article

Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone.

scientific article

Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity

scientific article published on 01 August 1997

Crx broadly modulates the pineal transcriptome.

scientific article

Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

scientific article

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.

scientific article published on 12 September 2008

Differential expression of miR-139, miR-486 and miR-21 in breast cancer patients sub-classified according to lymph node status

scientific article published on 01 June 2014

Distinct immune phenotypes in infants developing asthma during childhood

scientific article published on 01 February 2020

Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells.

scientific article published on June 2002

Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2.

scientific article

Effects of glucocorticoids on stratum corneum lipids and function in human skin-A detailed lipidomic analysis

scientific article

Efficient identification of miRNAs for classification of tumor origin.

scientific article published on 5 November 2013

Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

scientific article published on 01 January 1999

Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

scientific article published on 06 August 2019

Global microRNA analysis of the NCI-60 cancer cell panel

scientific article published on 20 January 2011

Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study

scientific article (publication date: 2012)

Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes

scientific journal article

HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

scientific article published on 04 March 2019

High expression of miR-21 in tumor stroma correlates with increased cancer cell proliferation in human breast cancer

scientific article published on 17 June 2011

Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin

scientific article

How the RNA isolation method can affect microRNA microarray results.

scientific article published on 6 December 2011

IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity.

scientific article

Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing

scientific article

Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2.

scientific article published on 17 August 2005

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.

scientific article published on January 2015

Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter

scientific article published on 21 July 2008

Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues.

scientific article published on 28 June 2005

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling

scientific article

Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways

scientific article published on 12 October 2015

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

scientific article published on December 2014

MicroRNA expression profiles associated with development of drug resistance in Ehrlich ascites tumor cells.

scientific article

MicroRNA expression profiling of the porcine developing brain

scientific article (publication date: 6 January 2011)

MicroRNAs and potential target interactions in psoriasis.

scientific article published on 17 March 2010

Molecular cloning of a K(+) channel from the malaria parasite Plasmodium falciparum

scientific article

Obtaining estimates for the ages of all the protein-coding genes and most of the ontology-identified noncoding genes of the human genome, assigned to 19 phylostrata

scientific article published on 08 December 2018

PolyHEMA spheroids are an inadequate model for the drug resistance of the intractable solid tumors.

scientific article published on 9 January 2008

Profiling the Atopic Dermatitis Epidermal Transcriptome by Tape Stripping and BRB-seq

scientific article published on 30 May 2022

Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study

scientific article published on 5 December 2017

Quantitative miRNA expression analysis: comparing microarrays with next-generation sequencing.

scientific article published on 10 September 2009

Regional Differences in Neuroinflammation-Associated Gene Expression in the Brain of Sporadic Creutzfeldt-Jakob Disease Patients

scientific article published on 25 December 2020

Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

scientific article published on 23 June 2008

Repeated monthly epicutaneous challenges with diphenylcyclopropenone result in a clinically reproducible level of contact allergy in de novo sensitized individuals

scientific article published on 07 February 2017

Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data

scientific article

STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma

scientific article published on 15 May 2013

Single-cell heterogeneity in Sézary syndrome

scientific article published on 01 August 2018

Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome

scientific article published on 14 May 2020

Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity

scientific article published on 01 August 1997

Temporal and Spatial Variation of the Skin-Associated Bacteria from Healthy Participants and Atopic Dermatitis Patients

scientific article published on 23 February 2022

The MicroRNA Expression Profile Differs Between Erythrodermic Mycosis Fungoides and Sézary Syndrome

scientific article published on 01 November 2019

The effect of short-chain fatty acids on human monocyte-derived dendritic cells

scientific article published on 6 November 2015

The gene expression and immunohistochemical time-course of diphenylcyclopropenone-induced contact allergy in healthy humans following repeated epicutaneous challenges.

scientific article

The immunoglobulin superfamily member CD200R identifies cells involved in type 2 immune responses

scientific article published on 20 January 2017

The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer.

scientific article published in July 2012

The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

scientific article published on 01 June 2000

The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

scientific article published on 01 April 2000

The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa.

scientific article published on 31 July 2012

Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate

scientific article

Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2.

scientific article published on September 2002

Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas

scientific article published on 29 July 2013

miR-155, identified as anti-metastatic by global miRNA profiling of a metastasis model, inhibits cancer cell extravasation and colonization in vivo and causes significant signaling alterations.

scientific article published on 10 August 2015

pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells.

scientific article published in January 1998

List of works by Thomas Litman

A Serial Analysis of Gene Expression (SAGE) database analysis of chemosensitivity: comparing solid tumors with cell lines and comparing solid tumors from different tissue origins.

A database study that identifies genes whose expression correlates, negatively or positively, with 5-year survival of cancer patients

ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

Adrenocortical Cancer: A Molecularly Complex Disease Where Surgery Matters

Ammonia and urea permeability of mammalian aquaporins.

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma

C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin

Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone.

Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity

Crx broadly modulates the pineal transcriptome.

Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.

Differential expression of miR-139, miR-486 and miR-21 in breast cancer patients sub-classified according to lymph node status

Distinct immune phenotypes in infants developing asthma during childhood

Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells.

Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2.

Effects of glucocorticoids on stratum corneum lipids and function in human skin-A detailed lipidomic analysis

Efficient identification of miRNAs for classification of tumor origin.

Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

Global microRNA analysis of the NCI-60 cancer cell panel

Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study

Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes

HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

High expression of miR-21 in tumor stroma correlates with increased cancer cell proliferation in human breast cancer

Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin

How the RNA isolation method can affect microRNA microarray results.

IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity.

Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing

Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2.

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.

Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter

Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues.

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling

Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

MicroRNA expression profiles associated with development of drug resistance in Ehrlich ascites tumor cells.

MicroRNA expression profiling of the porcine developing brain

MicroRNAs and potential target interactions in psoriasis.

Molecular cloning of a K(+) channel from the malaria parasite Plasmodium falciparum

Obtaining estimates for the ages of all the protein-coding genes and most of the ontology-identified noncoding genes of the human genome, assigned to 19 phylostrata

PolyHEMA spheroids are an inadequate model for the drug resistance of the intractable solid tumors.

Profiling the Atopic Dermatitis Epidermal Transcriptome by Tape Stripping and BRB-seq

Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study

Quantitative miRNA expression analysis: comparing microarrays with next-generation sequencing.

Regional Differences in Neuroinflammation-Associated Gene Expression in the Brain of Sporadic Creutzfeldt-Jakob Disease Patients

Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

Repeated monthly epicutaneous challenges with diphenylcyclopropenone result in a clinically reproducible level of contact allergy in de novo sensitized individuals

Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data

STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma

Single-cell heterogeneity in Sézary syndrome

Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome

Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity

Temporal and Spatial Variation of the Skin-Associated Bacteria from Healthy Participants and Atopic Dermatitis Patients

The MicroRNA Expression Profile Differs Between Erythrodermic Mycosis Fungoides and Sézary Syndrome

The effect of short-chain fatty acids on human monocyte-derived dendritic cells

The gene expression and immunohistochemical time-course of diphenylcyclopropenone-induced contact allergy in healthy humans following repeated epicutaneous challenges.

The immunoglobulin superfamily member CD200R identifies cells involved in type 2 immune responses

The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer.

The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa.

Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate

Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2.

Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas

miR-155, identified as anti-metastatic by global miRNA profiling of a metastasis model, inhibits cancer cell extravasation and colonization in vivo and causes significant signaling alterations.

pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells.