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List of works by Yoichiro Iwakura

1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells

scientific article published on 23 July 2010

A Crucial Role of RORγt in the Development of Spontaneous Sialadenitis-like Sjögren’s Syndrome

scientific article published on 19 November 2014

A Th17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-γ production in order to induce airway hyperresponsiveness

scientific article published on 25 May 2010

A class of large polysaccharides contains the antigenic determinants for the cytotoxic antibodies in a conventional syngeneic anti-F9 serum as well as a monoclonal antibody prepared against F9 cells ⬇️

scientific article published on September 1, 1983

A critical role for regulatory T cells in driving cytokine profiles of Th17 cells and their modulation of glioma microenvironment

scientific article published on 21 July 2011

A critical role of Dectin-1 in hypersensitivity pneumonitis

scientific article published on 7 December 2015

A new murine model to define the critical pathologic and therapeutic mediators of polymyositis

scientific article published on 01 April 2007

A novel DNA vaccine targeting macrophage migration inhibitory factor protects joints from inflammation and destruction in murine models of arthritis

scientific article published on 01 February 2007

A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury.

scientific article published in August 2002

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

scientific article published on June 2009

A role for leukocyte-derived IL-1RA in DC homeostasis revealed by increased susceptibility of IL-1RA-deficient mice to cutaneous leishmaniasis

scientific article published on 28 April 2011

Aberrant responses to acoustic stimuli in mice deficient for neural recognition molecule NB-2

scientific journal article

Aberrant tissue specific expression of the transgene in transgenic mice that carry the hepatitis B virus genome defective in the X gene.

scientific article published in January 1993

Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis

scientific journal article

Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway

scientific article published on 20 April 2010

Adiponectin Enhances Antibacterial Activity of Hematopoietic Cells by Suppressing Bone Marrow Inflammation

scientific article published on 14 June 2016

Agaricus brasiliensis-derived β-glucans exert immunoenhancing effects via a dectin-1-dependent pathway

scientific article published on 09 August 2012

Age-dependent regulation of depression-like behaviors through modulation of adrenergic receptor α₁A subtype expression revealed by the analysis of interleukin-1 receptor antagonist knockout mice.

scientific article published on 17 June 2011

Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene

scientific article published on 20 July 2007

Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis

scientific article published on 9 January 2014

Altered effector CD4+ T cell function in IL-21R-/- CD4+ T cell-mediated graft-versus-host disease

scientific article

An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells

scientific article published on 7 May 2014

Another road to interferon: Yasuichi Nagano's journey

scientific article published on May 2007

Anti-type II collagen antibody accelerates arthritisvia CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice

scientific article published on 01 October 2007

Antibiotic-killed Staphylococcus aureus induces destructive arthritis in mice

scientific article published on January 2015

Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

scientific article published in September 2002

Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity

scientific article

Arthritis in mice that are deficient in interleukin-1 receptor antagonist is dependent on genetic background

scientific article published on 01 December 2005

Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers

scientific article

Augmentation of c-fos and c-jun expression in transgenic mice carrying the human T-cell leukemia virus type-I tax gene.

scientific article published in January 1995

Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1.

scientific article published on October 2011

Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis

scientific journal article

Biosynthesis of RNA polymerase in Escherichia coli

scientific article published on 01 January 1974

Biotin status affects nickel allergy via regulation of interleukin-1beta production in mice

scientific article

Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner

scientific article published on November 2007

Bone marrow transplantation alters lung antigen-presenting cells to promote TH17 response and the development of pneumonitis and fibrosis following gammaherpesvirus infection

scientific article published on 16 September 2015

C-Type Lectin Receptors C-type lectin receptors in Host Defense Against Microbial Pathogens Pathogens

C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor

scientific journal article

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment

scientific article published on 17 April 2019

CCL2 recruitment of IL-6-producing CD11b+ monocytes to the draining lymph nodes during the initiation of Th17-dependent B cell-mediated autoimmunity

scientific article published in July 2008

CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis

scientific article published on 03 July 2019

CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes

scientific article published on 25 October 2014

CD11c+ Dendritic Cells Accelerate the Rejection of Older Cardiac Transplants via Interleukin-17A

scientific article published on 8 May 2015

CD28-dependent differentiation into the effector/memory phenotype is essential for induction of arthritis in interleukin-1 receptor antagonist–deficient mice

scientific article published on 01 February 2006

CD30 Ligand Is a Target for a Novel Biological Therapy against Colitis Associated with Th17 Responses

article

CD44 and Bak Expression in IL-6 or TNF-alpha Gene Knockout Mice After Whole Lung Irradiation

article

CTRP3 plays an important role in the development of collagen-induced arthritis in mice.

scientific article

CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis

scientific article

CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis

scientific article published on 12 October 2010

Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.

scientific article

Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

scientific article published on 01 November 1998

Characterization of mice deficient in melanocortin 2 receptor on a B6/Balbc mix background

scientific article published on 31 October 2008

Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages

scientific article (publication date: 2014)

Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor

scientific article published on 15 September 2021

Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression

scientific article published on 25 October 2013

Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice

scientific article published on 4 August 2014

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice ⬇️

scientific article published on 19 September 2012

Cloning of a novel 2',5'-oligoadenylate synthetase-like molecule, Oasl5 in mice

scientific journal article

Colitogenic effector T cells: roles of gut-homing integrin, gut antigen specificity and γδ T cells

scientific article published on 5 November 2013

Combined Interleukin-6 and Interleukin-1 Deficiency Causes Obesity in Young Mice

scientific article published on 01 April 2006

Combined deficiency of IL-1beta18, but not IL-1alphabeta, reduces susceptibility to hypoxia-ischemia in the immature brain

scientific article published in March 2005

Comparison of host resistance to primary and secondary Listeria monocytogenes infections in mice by intranasal and intravenous routes

scientific article

Comparison of polysaccharide synthesis between preimplantation stage mouse embryos and F9 embryonal carcinoma cells

scientific article published on 01 July 1983

Compensatory response of IL-1 gene knockout mice after pulmonary infection with Klebsiella pneumoniae

article

Contribution of IL-1 to resistance to Streptococcus pneumoniae infection

scientific article published on 01 July 2008

Contribution of interleukin 17A to the development and regulation of allergic inflammation in a murine allergic rhinitis model

scientific article published on 23 March 2012

Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice.

scientific article published on October 2014

Control of TH17 cells occurs in the small intestine.

scientific article

Critical role of Th17 cells in inflammation and neovascularization after ischaemia

scientific article published on 14 December 2010

Critical role of regulatory T cells in Th17-mediated minor antigen-disparate rejection

scientific article published on 23 August 2010

Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization.

scientific article

Cross reactivity of S. aureus to murine cytokine assays: A source of discrepancy

scientific article published on 12 March 2016

Crucial role of Bysl in mammalian preimplantation development as an integral factor for 40S ribosome biogenesis

scientific journal article

Cyclosporine A drives a Th17- and Th2-mediated posttransplant obliterative airway disease.

scientific article published on 17 January 2013

DCIR in the "osteo-immune" system

scientific article published on 9 October 2015

DCIR maintains bone homeostasis by regulating IFN-γ production in T cells

scientific article

Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells

scientific article published on 20 January 2008

Dectin-1 and Dectin-2 in innate immunity against fungi

scientific article (publication date: August 2011)

Dectin-1 and Dectin-2 promote control of the fungal pathogen Trichophyton rubrum independently of IL-17 and adaptive immunity in experimental deep dermatophytosis

scientific article published on 26 April 2016

Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation ⬇️

scientific article

Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans

scientific article published on 10 December 2006

Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells

scientific article published on 29 June 2016

Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans

scientific article

Dectin-2 promotes house dust mite-induced T helper type 2 and type 17 cell differentiation and allergic airway inflammation in mice

scientific article published in August 2014

Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans

scientific journal article

Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization

scientific article

Dectin-2-dependent NKT cell activation and serotype-specific antibody production in mice immunized with pneumococcal polysaccharide vaccine

scientific article

Dectin-2-dependent host defense in mice infected with serotype 3 Streptococcus pneumoniae

scientific article published on 5 January 2016

Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis

scientific article published on 06 June 2019

Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans

scientific article published on 27 January 2014

Deficiency of Interleukin-1 Receptor Antagonist Induces Aortic Valve Disease in BALB/c Mice

scientific article published on 28 January 2010

Deficiency of Interleukin-1 Receptor Antagonist Promotes Neointimal Formation After Injury

scientific article published on 21 July 2003

Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma

scientific article published on February 2009

Deficiency of interleukin-1 receptor antagonist deteriorates fatty liver and cholesterol metabolism in hypercholesterolemic mice

scientific article published in December 2004

Deficiency of tumour necrosis factor- and interferon- in bone marrow cells synergistically inhibits neointimal formation following vascular injury

scientific article published on 13 September 2008

Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor

Dendritic cell immunoreceptor 1 alters neutrophil responses in the development of experimental colitis

scientific article published on 23 October 2015

Desmoglein 3-specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice

scientific article

Development of experimental cerebral malaria is independent of IL-23 and IL-17.

scientific article published on 29 October 2010

Differential localization of colitogenic Th1 and Th2 cells monospecific to a microflora-associated antigen in mice.

scientific article

Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived β-glucans

scientific article

Differential role and tissue specificity of interleukin-1α gene expression in atherogenesis and lipid metabolism

article

Differential roles for IFN- and IL-17 in experimental autoimmune uveoretinitis

scientific article published on 21 December 2007

Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.

scientific article

Distinct role of T helper Type 17 immune response for Graves' hyperthyroidism in mice with different genetic backgrounds

scientific article published on 29 July 2010

Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model

scientific article

Diurnal variation of heart rate, locomotor activity, and body temperature in interleukin-1 alpha/beta doubly deficient mice

scientific article published in January 2002

Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling

scientific article published on February 2005

Dok-7 activates the muscle receptor kinase MuSK and shapes synapse formation

scientific article

Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse ⬇️

scientific article published on May 23, 2013

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

scientific article published in July 2008

Early activation and interferon-γ production of tumor-infiltrating mature CD27high natural killer cells

scientific article published on 21 August 2011

Early increase in mRNA levels of pro-inflammatory cytokines and their interactions in the mouse hippocampus after transient global ischemia

scientific article published on 13 December 2005

Ectopic cerebellar cell migration causes maldevelopment of Purkinje cells and abnormal motor behaviour in Cxcr4 null mice

scientific article

Effect of interleukin-6 neutralization on CYP3A11 and metallothionein-1/2 expressions in arthritic mouse liver.

scientific article published on 12 December 2006

Effective induction of acquired resistance to Listeria monocytogenes by immunizing mice with in vivo-infected dendritic cells

scientific article

Effects of tunicamycin on preimplantation mouse embryos: Prevention of molecular differentiation during blastocyst formation

scientific article published on 01 November 1985

Effects of tunicamycin on the differentiation of F9 cells induced by either retinoic acid or retinoic acid and dibutyryl cyclic AMP

scientific article published on 01 March 1987

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

scientific article published on 7 April 2008

Emergence of the Extrachromosomal Circular DNA Complexes as One of the Earliest Signals of Cellular Differentiation in the Early Development of Mouse Embryo. (mouse embryo/teratocarcinoma/mica-press-adsorption/circular DNA complex/DNA rearrangement)

article

Endogenous IL-17 Does Not Play a Significant Role in the Development of Experimental Murine Allergic Conjunctivitis

article

Endogenous Interleukin (IL)–1α and IL‐1β Are Crucial for Host Defense against Disseminated Candidiasis

scientific article published on 04 April 2006

Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma

scientific article published on 31 August 2012

Erratum: Corrigendum: Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

scholarly article published in Nature

Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production

scientific article

Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung

scientific article

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

scientific article published on 10 June 2002

Essential roles of Meltrin beta (ADAM19) in heart development

scientific journal article

Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation

scientific article published on 31 January 2018

Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-β-induced Foxp3 expression

scientific article

Expression of receptor protein tyrosine phosphatase δ, PTPδ, in mouse central nervous system

scientific article published on 26 March 2016

Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis

scientific article

Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus

scientific article

Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1 and TNF: Implications for Neuropathic Pain

scientific article published on 01 August 2011

Functional hypothalamic amenorrhea due to increased CRH tone in melanocortin receptor 2-deficient mice

scientific article published on 29 September 2010

Functional specialization of interleukin-17 family members

scientific article

Fungal allergen β-glucans trigger p38 mitogen-activated protein kinase-mediated IL-6 translation in lung epithelial cells

scientific article published on 3 June 2011

Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice

scientific article

Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation

scientific article (publication date: 2013)

Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice

scientific article

Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis

scientific article published on 04 October 2013

Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene family

scientific journal article

Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells

scientific journal article

HLA-B51 transgenic mice as recipients for production of polymorphic HLA-A, B-specific antibodies

scientific article published on 01 January 1993

Hepatic platelet accumulation in Fas-mediated hepatitis in mice

scientific article published on 9 May 2009

Histamine production via mast cell-independent induction of histidine decarboxylase in response to lipopolysaccharide and interleukin-1.

scientific article published in April 2004

Homeostatic defects in interleukin 18-deficient mice contribute to protection against the lethal effects of endotoxin

scientific article

Host defense against oral microbiota by bone-damaging T cells.

scientific article published on 16 February 2018

Human T-cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules

scientific article published on 22 September 2008

Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation

scientific article published on 04 December 2012

IFN- is a master regulator of endotoxin shock syndrome in mice primed with heat-killed Propionibacterium acnes

scientific article published on 03 February 2010

IFN-gamma expression in CD8+ T cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T cell death

scientific article published on 2 December 2008

IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis

scientific article

IFN-gamma-regulated Toxoplasma gondii distribution and load in the murine eye.

scientific article published in October 2003

IFN-γ and TNF-α are involved in urushiol-induced contact hypersensitivity in mice

scientific article published on 01 February 2005

IL-1 is required for allergen-specific Th2 cell activation and the development of airway hypersensitivity response

scientific article published in April 2003

IL-1 is required for tumor invasiveness and angiogenesis ⬇️

scientific journal article

IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions

scientific journal article

IL-1 plays an important role in the bone metabolism under physiological conditions

scientific article published on 02 August 2010

IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ

scientific article

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells

scientific article published on 25 June 2015

IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages

scientific article published on 27 February 2015

IL-1 receptor-antagonist (IL-1Ra) knockout mice show anxiety-like behavior by aging

scientific article published on 19 May 2015

IL-1 regulates the Cyp7a1 gene and serum total cholesterol level at steady state in mice

scientific article

IL-1 signalling is dispensable for protective immunity in Leishmania-resistant mice

scientific article published on 18 October 2010

IL-1-induced tumor necrosis factor-alpha elicits inflammatory cell infiltration in the skin by inducing IFN-gamma-inducible protein 10 in the elicitation phase of the contact hypersensitivity response

scientific article

IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model

article

IL-17 contributes to CD4-mediated graft-versus-host disease

scientific article published on 17 October 2008

IL-17 is involved in Helicobacter pylori-induced gastric inflammatory responses in a mouse model.

scientific article published on December 2008

IL-17 is involved in bone resorption in mouse periapical lesions

scientific article

IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection

scientific article published on 18 June 2010

IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

scientific article

IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice

scientific article published on March 2009

IL-17-producing γδ T cells enhance bone regeneration

scientific article published on 11 March 2016

IL-17A as an Inducer for Th2 Immune Responses in Murine Atopic Dermatitis Models

article

IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice

scientific article published on 20 January 2013

IL-17A is produced by Th17, gammadelta T cells and other CD4- lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance

scientific article published on 3 July 2008

IL-17A mediates early post-transplant lesions after heterotopic trachea allotransplantation in Mice

scientific article

IL-17A promotes fatty acid uptake through the IL-17A/IL-17RA/p-STAT3/FABP4 axis to fuel ovarian cancer growth in an adipocyte-rich microenvironment

scientific article published on 04 December 2019

IL-17A promotes macrophage effector mechanisms against Trypanosoma cruzi by trapping parasites in the endolysosomal compartment

scientific article published on 26 October 2012

IL-17A-producing CD30(+) Vδ1 T cells drive inflammation-induced cancer progression

scientific article published on 6 July 2016

IL-18 gene therapy develops Th1-type immune responses in Leishmania major-infected BALB/c mice: is the effect mediated by the CpG signaling TLR9?

scientific article published in June 2004

IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice

scientific article

IL-1β, but not IL-1α, is required for antigen-specific T cell activation and the induction of local inflammation in the delayed-type hypersensitivity responses

article

IL-21 inhibits IL-17A-producing γδ T-cell response after infection with Bacillus Calmette-Guérin via induction of apoptosis

scientific article published on 22 August 2016

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

scientific article

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

scientific article published on 11 September 2008

IL-23 in Colitis: Targeting the Progenitors

scientific article published on 01 December 2012

IL-23 protection against Plasmodium berghei infection in mice is partially dependent on IL-17 from macrophages

scientific article published on 19 August 2013

IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis

scientific article

IL-36α exerts pro-inflammatory effects in the lungs of mice

scientific article

IL-36α from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop

scientific article published on 23 May 2018

IL-6 amplifier, NF-κB-triggered positive feedback for IL-6 signaling, in grafts is involved in allogeneic rejection responses

scientific article published on 13 July 2012

IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse

scientific article published in Scientific Reports

IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells

scientific article

IL-9 promotes Th17 cell migration into the central nervous system via CC chemokine ligand-20 produced by astrocytes

scientific article published on 23 February 2011

IL1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-κB Activation.

scientific article published on 23 October 2015

INTERFERON γ PRIMING IS NOT CRITICAL FOR IL-12 PRODUCTION OF MURINE SPLEEN CELLS

scientific article published on 01 January 2000

Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T

scientific article

Identification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis

scientific article published on January 2006

Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.

scientific article published on 10 March 2010

Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo

scientific article

Immune complexes inhibit IL-1 secretion and inflammasome activation

scientific article published on 15 October 2014

Immunogenicity of Peptide-25 of Ag85B in Th1 development: role of IFN-

article

Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup

scientific article published in September 2003

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4-galactosyltransferase-I-deficient mice

scientific journal article

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

scientific article

Increased Expression of Interleukin-1.BETA. in Mouse Hippocampus after Global Cerebral Ischemia

Induction of Autoimmune Thyroiditis by Depletion of CD4+CD25+Regulatory T Cells in Thyroiditis-Resistant IL-17, But Not Interferon-γ Receptor, Knockout Nonobese Diabetic-H2h4Mice

scientific article published on 23 August 2011

Induction of thymic stromal lymphopoietin production by xylene and exacerbation of picryl chloride-induced allergic inflammation in mice.

scientific article published on 7 October 2011

Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis

scientific article published on 7 July 2010

Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice

scientific article published on 06 January 2014

Inhibition of B16 melanoma experimental metastasis by interferon-gamma through direct inhibition of cell proliferation and activation of antitumour host mechanisms

article by Shigeru Kakuta et al published January 2002 in Immunology

Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine

scientific article

Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation

scientific article published on 06 June 2018

Innate Immune Functions of Astrocytes are Dependent Upon Tumor Necrosis Factor-Alpha

scientific article published on 27 April 2020

Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection

scientific article

Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection

scholarly article by Nelson C. Di Paolo et al published February 2016 in Immunity

Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice.

scientific article published in November 2006

Interferon-gamma production and host protective response against Mycobacterium tuberculosis in mice lacking both IL-12p40 and IL-18.

scientific article published in April 2004

Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

scientific article

Interleukin (IL)-6, but not IL-1, induction in the brain downstream of cyclooxygenase-2 is essential for the induction of febrile response against peripheral IL-1alpha

scientific article published on 22 July 2004

Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction

scientific article

Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells.

scientific article

Interleukin-1 beta, but not interleukin-1 alpha, is required for T-cell-dependent antibody production

scientific article published on 01 December 2001

Interleukin-1 controls the constitutive expression of the Cyp7a1 gene by regulating the expression of Cyp7a1 transcriptional regulators in the mouse liver

scientific article

Interleukin-1 deficiency in combination with macrophage depletion increases susceptibility to Pseudomonas aeruginosa bacteremia

scientific article published in September 2009

Interleukin-1 is not essential for expression of inducible NOS in hepatocytes induced by lipopolysaccharide in vivo

scientific article published on 11 April 2007

Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

scientific article published on 7 April 2012

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule

scientific journal article

Interleukin-1-deficient mice exhibit high sensitivity to gut-derived sepsis caused by Pseudomonas aeruginosa

scientific article published on 2 April 2005

Interleukin-1-dependent sequential chemokine expression and inflammatory cell infiltration in ischemia-reperfusion injury

scientific article published on 01 September 2006

Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice.

scientific article published on 28 February 2012

Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis

scientific article

Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction

scientific article published on 9 October 2008

Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

scientific article published on 15 December 2013

Interleukin-17-producing γδ T (γδ17) cells in inflammatory diseases

Interleukin-17A Deficiency Accelerates Unstable Atherosclerotic Plaque Formation in Apolipoprotein E-Deficient Mice

scientific article published on 23 November 2011

Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy

scientific article published on 08 April 2010

Interleukin-17A Promotes Aortic Endothelial Cell Activation via Transcriptionally and Post-translationally Activating p38 Mitogen-activated Protein Kinase (MAPK) Pathway

scientific article published on 5 January 2016

Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension

scientific article published on 02 May 2016

Interleukin-17A contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and neutrophil infiltration.

scientific article published on January 2012

Interleukin-17A during local and systemic Staphylococcus aureus-induced arthritis in mice.

scientific article

Interleukin-17A is involved in enhancement of tumor progression in murine intestine

scientific article published on 10 September 2011

Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice

scientific article

Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors

scientific article

Interleukin-18 induces expression and release of cytokines from murine glial cells: interactions with interleukin-1 beta

scientific article

Interleukin-1alphabeta gene-deficient mice show reduced nociceptive sensitivity in models of inflammatory and neuropathic pain but not post-operative pain

scientific article published on 26 October 2005

Interleukin-1beta abrogates long-term depression of hippocampal CA1 synaptic transmission

scientific article published in January 2003

Interleukin-1β and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA-induced matrix metalloproteinase-1 expression

scientific article published on 03 December 2007

Interleukin-1β induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis

scientific article published on 3 August 2013

Interleukin-1β–Driven Inflammation Promotes the Development and Invasiveness of Chemical Carcinogen–Induced Tumors

scientific article published on 01 February 2007

Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis

scientific article published on April 2008

Interleukin-4 (IL-4) and IL-13 suppress excessive neutrophil infiltration and hepatocyte damage during acute murine schistosomiasis japonica

scientific article published on 28 October 2011

Interleukin-4 and interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon.

scientific article published on May 2000

Intestinal inflammation downregulates smooth muscle CPI-17 through induction of TNF-α and causes motility disorders

scientific article published on 15 February 2007

Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.

scientific article published on 05 March 2014

Involvement of Gr-1dull+ Cells in the Production of TNF-α and IL-17 and Exacerbated Systemic Inflammatory Response Caused by Lipopolysaccharide

scientific article published on 01 February 2014

Involvement of IL-1 family proteins in p38 linked cellular senescence of mouse embryonic fibroblasts

scientific article published on 01 September 2004

Involvement of IL-17 in Fas ligand-induced inflammation

scientific article published on 5 July 2004

Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice

scientific article published on 15 September 2008

Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour

scientific article

Involvement of Tumor Necrosis Factor-α in the Development of T Cell–Dependent Aortitis in Interleukin-1 Receptor Antagonist–Deficient Mice

article

Involvement of corticotropin-releasing hormone- and interleukin (IL)-6-dependent proopiomelanocortin induction in the anterior pituitary during hypothalamic-pituitary-adrenal axis activation by IL-1alpha

scientific article

Involvement of interleukin-1 in lead nitrate-induced hypercholesterolemia in mice

scientific article

Involvement of interleukin-17A-induced hypercontractility of intestinal smooth muscle cells in persistent gut motor dysfunction

scientific article

Involvement of interleukin-6 and tumor necrosis factor alpha in CYP3A11 and 2C29 down-regulation by Bacillus Calmette-Guerin and lipopolysaccharide in mouse liver

scientific article published in July 2004

Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression

scientific article published in October 2007

Involvement of tumor necrosis factor α, rather than interleukin-1α/β or nitric oxides in the heme oxygenase-1 gene expression by lipopolysaccharide in the mouse liver

article

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

scientific article published on 01 January 2001

Kid-mediated chromosome compaction ensures proper nuclear envelope formation

scientific article published in March 2008

Kjellmaniella crassifolia Miyabe (Gagome) extract modulates intestinal and systemic immune responses

scientific article published on 7 November 2011

Knockout mice lacking cPGES/p23, a constitutively expressed PGE2 synthetic enzyme, are peri-natally lethal

scientific article published on 9 August 2007

Knockout of mouse beta 1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteins

scientific article

Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

scientific article published on 27 February 2003

Lack of interleukin-1 receptor antagonist modulates plaque composition in apolipoprotein E-deficient mice

scientific article published in April 2004

Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis

scientific article

Lipopolysaccharide promotes and augments metal allergies in mice, dependent on innate immunity and histidine decarboxylase.

scientific article published on May 2007

Lipopolysaccharide-induced HIV-1 expression in transgenic mice is mediated by tumor necrosis factor-α and interleukin-1, but not by interferon-γ nor interleukin-6

article

Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis.

scientific article published on 28 August 2015

Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells ⬇️

scientific article published on 10 January 2011

Local microbleeding facilitates IL-6– and IL-17–dependent arthritis in the absence of tissue antigen recognition by activated T cells.

scientific article published in November 2012

Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets

scientific article published in October 2006

Lung CD4-CD8- double-negative T cells are prominent producers of IL-17A and IFN-gamma during primary respiratory murine infection with Francisella tularensis live vaccine strain

scientific article published on 14 April 2010

MAIT cells protect against pulmonary Legionella longbeachae infection ⬇️

scientific article published in Nature Communications

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

scientific article published on February 2013

MHC-Matched Corneal Allograft Rejection in an IFN-γ/IL-17–Independent Manner in C57BL/6 Mice

scientific article published on 10 January 2009

Mammalian Motoneuron Axon Targeting Requires Receptor Protein Tyrosine Phosphatases and

scientific article published on 01 May 2006

Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1

scholarly article

Mast cells mediate malignant pleural effusion formation.

scientific article

Mature dendritic cell suppression by IL-1 receptor antagonist on retinal pigment epithelium cells

scientific article published on 7 May 2013

Mechanism of Blastocyst Formation of the Mouse Embryo. (mouse embryo/blastocyst formation/ polarization/cell interaction/t12mutation/tunicamycin)

Mechanism of pro-tumorigenic effect of BMP-6: neovascularization involving tumor-associated macrophages and IL-1a

scientific article published on February 2014

Megakaryocytes compensate for Kit insufficiency in murine arthritis.

scientific article

Melanocortin 2 receptor is required for adrenal gland development, steroidogenesis, and neonatal gluconeogenesis

scholarly article

Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology ⬇️

scientific article

Mesenteric lymph nodes contribute to proinflammatory Th17-cell generation during inflammation of the small intestine in mice

scientific article published on 17 February 2016

Mice deficient in nervous system-specific carbohydrate epitope HNK-1 exhibit impaired synaptic plasticity and spatial learning

scientific article published on 24 May 2002

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking

scientific journal article

Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye.

scientific article published on 26 February 2016

Mouse model for PTPRD associations with WED/RLS and addiction: reduced expression alters locomotion, sleep behaviors and cocaine-conditioned place preference

scientific article published on 14 July 2015

Multiple CD11c+ cells collaboratively express IL-1β to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth

scientific article

Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).

scientific article

Mutual augmentation of the induction of the histamine-forming enzyme, histidine decarboxylase, between alendronate and immuno-stimulants (IL-1, TNF, and LPS), and its prevention by clodronate

scientific article

Mutually exclusive expression of odorant receptor transgenes

scientific article published on 01 July 2000

Myeloid C-type lectin receptors in skin/mucoepithelial diseases and tumors

scientific article published on 09 April 2019

Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.

scientific article published on 14 February 2018

NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant

scientific article published on 28 March 2011

NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β

scientific article

NLRP3 regulates neutrophil functions and contributes to hepatic ischemia-reperfusion injury independently of inflammasomes

scientific article published on 2 April 2014

NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity

scientific article

NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons

scientific article

Natural killer T cell-derived IL-17 mediates lung ischemia-reperfusion injury

scientific article

Natural killer T cells from interleukin-4-deficient mice are defective in early interferon-? production in response to ?-galactosylceramide

scientific article published on 14 March 2007

Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation

scientific article

Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages

article

Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice

scientific article

Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia.

scientific article

Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice

scientific article

Neutrophils are essential as a source of IL-17 in the effector phase of arthritis

scientific article

Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling

scientific article

Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist

scientific article

Noninvasive in vivo imaging to evaluate immune responses and antimicrobial therapy against Staphylococcus aureus and USA300 MRSA skin infections

scientific article

Normal levels of serum glycoproteins maintained in β-1,4-galactosyltransferase I-knockout mice

scientific article published on 01 December 1999

Notch-Hes1 pathway is required for the development of IL-17-producing T cells

article

Nuclear import of the preintegration complex is blocked upon infection by human immunodeficiency virus type 1 in mouse cells

scientific article published on November 2006

Nucleoprotein Diet Ameliorates Arthritis Symptoms in Mice Transgenic for Human T-Cell Leukemia Virus Type I (HTLV-1)

scientific article

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

scientific article published on 26 June 2013

Osteopontin regulates interleukin-17 production in hepatitis.

scientific article

Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice

scientific journal article

Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17

scientific article published on 4 February 2008

PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia

scientific article published on 10 July 2015

Pam3CSK(4) enhanced beta cell loss and diabetogenesis: the roles of IFN-gamma and IL-17.

scientific article published on 13 June 2013

Panax ginseng induces production of proinflammatory cytokines via toll-like receptor

scientific article published on February 2004

Participation of endogenously produced interferon gamma in interleukin 4-mediated tumor rejection.

scientific article

Peripheral TNFalpha, but not peripheral IL-1, requires endogenous IL-1 or TNFalpha induction in the brain for the febrile response

scientific article

Periprosthetic osteolysis: Characterizing the innate immune response to titanium wear-particles

scholarly article by Christine A. St. Pierre et al published 22 November 2010 in Journal of Orthopaedic Research

Periprosthetic osteolysis: characterizing the innate immune response to titanium wear-particles

scientific article published on November 2010

Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin

scientific article published on 21 September 2014

Persistent release of IL-1s from skin is associated with systemic cardio-vascular disease, emaciation and systemic amyloidosis: the potential of anti-IL-1 therapy for systemic inflammatory diseases

scientific article

Phenotypic analysis of Meltrin alpha (ADAM12)-deficient mice: involvement of Meltrin alpha in adipogenesis and myogenesis

scientific article

Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17

scientific article published on 16 February 2007

Phosphoinositide 3-Kinase δ Regulates Dectin-2 Signaling and the Generation of Th2 and Th17 Immunity

scientific article published on 18 May 2016

Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity

scientific article published on 21 April 2017

Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.

scholarly article

Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury

scientific article published on 2 August 2009

Polylactosamine synthesis and branch formation of N-glycans in beta1,4-galactosyltransferase-1-deficient mice

scientific journal article

Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity

scientific article published on 02 January 2014

Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock

scientific article

Potential roles of interleukin-17A in the development of skin fibrosis in mice

scientific article

Presence of A Higher Molecular Weight .BETA.-1,4-Galactosyltransferase in Mouse Liver

Presence of a common structure in the two molecular species of mouse L cell interferon

scientific article published on 01 October 1978

Presence of polysialic acid and HNK-1 carbohydrate on brain glycoproteins from beta-1,4-galactosyltransferase-knockout mice

scientific journal article

Primary role of interleukin-1 alpha and interleukin-1 beta in lipopolysaccharide-induced hypoglycemia in mice

scientific article

Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production

scientific article published on 12 November 2001

Production of IL-17A at Innate Immune Phase Leads to Decreased Th1 Immune Response and Attenuated Host Defense against Infection with Cryptococcus deneoformans

scientific article published on 19 June 2020

Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion ⬇️

scientific article published on May 4, 1998

Protective role of IL-1β against post-arthroplasty Staphylococcus aureus infection

scientific article published on 28 March 2011

Protective role of naturally occurring interleukin-17A-producing γδ T cells in the lung at the early stage of systemic candidiasis in mice

scientific article

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

scientific article

Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signaling

scientific article published on 26 June 2009

Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism

scientific article published in February 2002

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

scientific article published on 26 May 2013

RNA packaging signal of human immunodeficiency virus type 1

scientific article published on June 1, 1992

RNA polymerase mutants of Escherichia coli. Streptolydigin resistance and its relation to rifampicin resistance.

scientific article

Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis

scientific article

Rapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotype

scientific article

Rapid purification of mouse L cell interferon labeled with radioactive amino acid by immune precipitation

scientific article published on 01 January 1980

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

scientific article published on 14 July 2009

Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

scientific article

Reduced postischemic apoptosis in the hippocampus of mice deficient in interleukin-1.

scientific article published in June 2002

Reduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidase

scientific article (publication date: 2012)

Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier

scientific article published in February 2012

Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis

scientific article published on 19 February 2016

Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production

scientific article

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

scientific article published on 15 November 2012

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene

scientific article published on 2 February 2007

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide

scientific article published on 01 March 2002

Role of Crk-associated substrate lymphocyte type in the pathophysiology of rheumatoid arthritis in tax transgenic mice and in humans

scientific article published in July 2003

Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia

scientific article published on December 2004

Role of IFN-gamma and tumor necrosis factor-alpha in herpes simplex virus type 1 infection

scientific article published in June 2002

Role of T cell TGFbeta signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection

scientific article published on 16 November 2009

Role of interferon-gamma in the development of murine bronchus-associated lymphoid tissues induced by silica in vivo

scientific article published in November 2002

Role of interferon-γ in Vα14+ natural killer T cell-mediated host defense against Streptococcus pneumoniae infection in murine lungs

scientific article published on 09 January 2007

Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice

scientific article

Role of interleukin-17A in cell-mediated protection against Staphylococcus aureus infection in mice immunized with the fibrinogen-binding domain of clumping factor A.

scientific article published on 2 August 2010

Roles of IFN-gamma on stage conversion of an obligate intracellular protozoan parasite, Toxoplasma gondii

scientific article

Roles of IL-1 in the development of rheumatoid arthritis: consideration from mouse models

scientific article

Roles of RecJ, RecO, and RecR in RecET-mediated illegitimate recombination in Escherichia coli

scientific article published on September 2002

Roles of endogenous cytokines in liver apoptosis of mice in lethal Listeria monocytogenes infection

scientific article published on 01 August 2000

Roles of gamma interferon and tumor necrosis factor-alpha in shiga toxin lethality

scientific article

Roles of interleukin-17 in an experimental Legionella pneumophila pneumonia model

scientific article published on 5 December 2011

Secretory IgA antibodies provide cross-protection against infection with different strains of influenza B virus

scientific article published in October 2004

Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocytes/macrophages

scientific article published on 18 May 2006

Significant Antitumor Effects Obtained by Autologous Tumor Cell Vaccine Engineered to Secrete Interleukin (IL)-12 and IL-18 by Means of the EBV/Lipoplex

scientific article published on 01 May 2002

Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis

scientific journal article

Six4, a putative myogenin gene regulator, is not essential for mouse embryonal development.

scientific article

Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia

scientific article published on 22 February 2013

Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β

scientific article published on 29 April 2019

Stage-specific roles for CXCR4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation

scientific article published in July 2014

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

scientific article published on 30 April 2010

Structural changes in the N-linked sugar chains of serum immunoglobulin G of HTLV-I transgenic mice.

scientific article published in May 1993

Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota

scientific article published on 18 June 2018

Suppression of autoimmune arthritis in interleukin-1-deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells.

scientific article published in February 2002

Suppression of oxidative neuronal damage after transient middle cerebral artery occlusion in mice lacking interleukin-1.

scientific article published in March 2003

Suppressive role of leukocyte cell–derived chemotaxin 2 in mouse anti–type II collagen antibody–induced arthritis

scientific article published on 01 February 2008

Synthesis and distribution of carbohydrate chains in cleavage-stage mouse embryos carrying the t12 lethal mutation

scientific article published on 01 August 1988

Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17.

scientific article published on 10 November 2011

T Cell Apoptosis Causes Peripheral T Cell Depletion in Mice Transgenic for the HIV-1 vpr Gene

article

T Helper Type 17 Immune Response Plays an Indispensable Role for Development of Iodine-Induced Autoimmune Thyroiditis in Nonobese Diabetic-H2h4Mice

scientific article published on 24 September 2009

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis.

scientific article published on 16 January 2007

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis

scientific article published on 21 March 2016

T cells accumulating in the inflamed joints of a spontaneous murine model of rheumatoid arthritis become restricted to common clonotypes during disease progression

scientific article

TNF, but Not IL-6 and IL-17, Is Crucial for the Development of T Cell-Independent Psoriasis-Like Dermatitis in Il1rn-/- Mice

article

TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

scientific article

TNF-α is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist–deficient mice

Targeting IL-1β and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation

scientific article

Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis

scientific article

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

scientific article published on 6 November 2006

The Arf GAP SMAP2 is necessary for organized vesicle budding from the trans-Golgi network and subsequent acrosome formation in spermiogenesis

scientific article published on 17 July 2013

The IL-23/IL-17 axis in inflammation

scientific article published on May 2006

The NLRP12 Inflammasome Recognizes Yersinia pestis

scholarly article by Gregory I. Vladimer et al published September 2012 in Immunity

The NLRP12 inflammasome recognizes Yersinia pestis

scientific article published on July 2012

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

article by Hiromitsu Hara et al published 7 May 2007 in Nature Immunology

The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1alphabeta knockout mice

scientific article

The mechanism of LPS-induced HIV type I activation in transgenic mouse macrophages.

scientific article published on 26 May 2010

The muscle protein Dok-7 is essential for neuromuscular synaptogenesis

scientific article

The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation

scientific article

The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis

scientific article published in March 2004

The role of Syk/CARD9 coupled C-type lectins in antifungal immunity

scientific article published on 11 January 2011

The role of endogenous glucocorticoids in lymphocyte development in melanocortin receptor 2-deficient mice

scientific article published on 5 November 2010

The role of gamma interferon in acquired host resistance againstStaphylococcus aureusinfection in mice

scientific article published on 01 April 2006

The role of glucocorticoids in pregnancy, parturition, lactation, and nurturing in melanocortin receptor 2-deficient mice

scientific article

The roles of IL-17A in inflammatory immune responses and host defense against pathogens

scientific article published on December 2008

Therapeutic effects of interleukin-6 blockade in a murine model of polymyositis that does not require interleukin-17A

scientific article published on 01 August 2009

Toll-like receptor 2 (TLR2) and dectin-1 contribute to the production of IL-12p40 by bone marrow-derived dendritic cells infected with Penicillium marneffei

scientific article

Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors ⬇️

scientific article published on 19 January 2012

Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans

scientific article published on 11 May 2009

Toxoplasma gondii infection inhibits Th17-mediated spontaneous development of arthritis in interleukin-1 receptor antagonist-deficient mice

scientific article published on 30 January 2012

Toxoplasma gondii: difference of invasion into tissue of digestive organs between susceptible and resistant strain and influence of IFN-gamma in mice inoculated with the cysts perorally

scientific article

Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung

scientific article

Transforming Growth Factor-β Regulates Susceptibility of Epithelial Apoptosis in Murine Model of Colitis

scientific article published on 01 December 2004

Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells

scientific article published on 17 December 2013

Transgenic mice carrying interferon genes

article

Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease

scientific article

Tumor necrosis factor-α is required for gastritis induced by Helicobacter felis infection in mice

scientific article published on 01 September 2004

Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor by promoting angiogenesis

scientific article published on July 2010

Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections

scientific article

Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis

scientific article published on 16 November 2009

Upregulation of Polymeric Immunoglobulin Receptor Expression by the Heat-Inactivated Potential Probiotic Bifidobacterium bifidum OLB6378 in a Mouse Intestinal Explant Model

article

Vaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78/MTJ-1 complex

scientific journal article

Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo

scientific article published on 2 July 2009

Visceral Adipose Tissue-derived Serine Proteinase Inhibitor Inhibits Apoptosis of Endothelial Cells as a Ligand for the Cell-Surface GRP78/Voltage-dependent Anion Channel Complex

scientific article published on 10 January 2013

[Mouse models for rheumatoid arthritis and their use in drug development].

scientific article published in November 2002

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

scientific article published on 4 March 2015

β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner.

scientific article

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