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List of works by Kunitoshi Mitsumori

A 26-week carcinogenicity study of 2-amino-3-methylimidazo[4,5-f]quinoline in rasH2 mice.

scientific article published in January 2006

A Japanese view on a global toxicology testing program before ICH1 and after ICH4

scientific article published on 01 December 1998

A case report of a renal mixed epithelial and stromal tumor in a heterozygous S1P2 receptor deficient mouse.

scientific article published in May 2008

A case report of an uncommon sex-cord stromal tumor consisted of luteal and sertoli cells in a spayed bitch

scientific article published on 25 November 2009

A histological study of the cardiac conduction system in a heifer with complete atrioventricular block

scientific article published on 01 July 2005

A mixed apocrine gland tumor with metastases to the bone and bone marrow in a miniature poodle.

scientific article published on 30 June 2010

A neuroendocrine carcinoma of undetermined origin in a dog.

scientific article

A spontaneous seminal vesicle adenocarcinoma in an aged F344 rat

scientific article published on 01 May 1998

Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats.

scientific article published on 25 March 2013

Aberrant activation of ubiquitin D at G2 phase and apoptosis by carcinogens that evoke cell proliferation after 28-day administration in rats.

scientific article

Aberrant expression of cyclin D1 in pulmonary proliferative lesions induced by high doses of urethane in transgenic mice carrying the human prototype c-H-ras gene.

scientific article published in March 2001

Aberration in epigenetic gene regulation in hippocampal neurogenesis by developmental exposure to manganese chloride in mice.

scientific article published on 23 August 2013

Absence of in vivo genotoxic potential and tumor initiation activity of kojic acid in the rat thyroid.

scientific article

Absence of in vivo genotoxicity and liver initiation activity of dicyclanil.

scientific article published in August 2003

Absence of liver tumor-initiating activity of kojic acid in mice.

scientific article published on 18 October 2005

Adolescent hyperactivity of offspring after maternal protein restriction during the second half of gestation and lactation periods in rats.

scientific article published in January 2012

Amelanotic melanocytic tumors of the pinna in six F344 rats ⬇️

scientific article published on April 1, 1991

An outbreak of esophagectasis in F344 rats

scientific article published on 01 June 1986

An ultrastructural study of spinal nerve roots and dorsal root ganglia in aging rats with spontaneous radiculoneuropathy

scientific article published on 01 November 1981

Analysis of proliferative activity in renal lesions induced by N-nitrosobis(2-oxopropyl)amine (BOP) in male Syrian golden hamsters

scientific article published on 01 April 1994

Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats.

scientific article published on January 2011

Antioxidant enzymatically modified isoquercitrin or melatonin supplementation reduces oxidative stress-mediated hepatocellular tumor promotion of oxfendazole in rats.

scientific article published on 22 December 2009

Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone.

scientific article published on 5 January 2010

Apolipoprotein A-II suppressed concanavalin A-induced hepatitis via the inhibition of CD4 T cell function

scientific article published on 07 February 2011

Assessment of renal toxicity by analysis of regeneration of tubular epithelium in rats given low-dose cadmium chloride or cadmium-polluted rice for 22 months

scientific article published on 01 December 2000

Cadmium accumulation in rats treated orally with cadmium chloride for 8 months

scientific article published on 01 August 1998

Carcinogen dose-dependent variation in the transgene mutation spectrum in urethane-induced lung tumors in transgenic mice carrying the human prototype c-Ha-ras gene

scientific article

Carcinogenic susceptibility of rasH2 mice to troglitazone.

scientific article published on 14 June 2007

Carcinogenic susceptibility to N-bis(2-hydroxypropyl)nitrosamine (DHPN) in rasH2 mice.

scientific article

Carcinogenicity of N-nitroso-ethylenethiourea in female mice

scientific article published on 01 October 1979

Carcinogenicity of methylmercury chloride in ICR mice: preliminary note on renal carcinogenesis

scientific article published on 01 May 1981

Cellular distribution of cell cycle-related molecules in the renal tubules of rats treated with renal carcinogens for 28 days: relationship between cell cycle aberration and carcinogenesis.

scientific article published on 13 March 2012

Chronic toxicity and carcinogenicity of dietary administered ammonium sulfate in F344 rats

scientific article published on 15 July 2005

Chronic toxicity and carcinogenicity of methylmercury chloride in B6C3F1 mice

scientific article published on 01 January 1990

Chronic toxicity of methylmercury chloride in rats: clinical study and chemical analysis

scientific article published on 01 December 1983

Chronic toxicity of methylmercury chloride in rats: pathological study

scientific article published on 01 August 1984

Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage-associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium.

scientific article published on 22 April 2008

Combined treatment with green tea catechins and sodium nitrite selectively promotes rat forestomach carcinogenesis after initiation with N-methyl-N'- nitro-N-nitrosoguanidine.

scientific article

Complex apocrine carcinoma with dominant myoepithelial proliferation in a dog.

scientific article

Comprehensive analysis of DNA methylation and gene expression of rat liver in a 2-stage hepatocarcinogenesis model

scientific article published on January 2014

Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by β-naphthoflavone involving TNFα-signaling due to oxidative cellular stress in rats.

scientific article published on 2 February 2011

Concurrent administration of ascorbic acid enhances liver tumor-promoting activity of kojic acid in rats.

scientific article published in May 2008

Confirmation study, using nitrobenzene, of the Combined Repeat Dose and Reproductive/Developmental Toxicity Test protocol proposed by the Organization for Economic Cooperation and Development (OECD).

scientific article published in August 1994

Correlation between nucleolar organizer regions and cell proliferation in pancreatic acinar cell proliferative lesions in rats

scientific article published on 01 March 1994

Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma

scientific article published on February 2009

Detection of initiating potential of non-genotoxic carcinogens in a two-stage hepatocarcinogenesis study in rats.

scientific article published on January 2014

Detection of oxidative DNA damage, cell proliferation and in vivo mutagenicity induced by dicyclanil, a non-genotoxic carcinogen, using gpt delta mice.

scientific article published on 18 May 2007

Development of pericardial mesothelioma in golden retrievers with a long-term history of idiopathic haemorrhagic pericardial effusion

scientific article published on 01 August 2004

Developmental Exposure to Manganese Chloride Induces Sustained Aberration of Neurogenesis in the Hippocampal Dentate Gyrus of Mice ⬇️

scientific article published on March 9, 2012

Developmental toxicity of brominated flame retardants, tetrabromobisphenol A and 1,2,5,6,9,10-hexabromocyclododecane, in rat offspring after maternal exposure from mid-gestation through lactation.

scientific article

Direct progression of capsular invasive carcinomas from subcapsular focal hyperplasias induced by hypothyroidism-mediated tumor promotion in a rat two-stage thyroid carcinogenesis model ⬇️

scientific article published on November 1, 2012

Disruption of Smad-dependent signaling for growth of GST-P-positive lesions from the early stage in a rat two-stage hepatocarcinogenesis model.

scientific article published on 25 April 2010

Disruptive cell cycle regulation involving epigenetic downregulation of Cdkn2a (p16(Ink4a)) in early-stage liver tumor-promotion facilitating liver cell regeneration in rats.

scientific article published on 30 May 2012

Dose-response relationship of promotion by phenobarbital in rat two-stage hepatocarcinogenesis

scientific article (publication date: 1991)

Dose-threshold for thyroid tumor-promoting effects of xylazine in rats.

scientific article published on June 2003

Doxorubicin induces male germ cell apoptosis in rats

scientific article published on 01 June 1999

Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model.

scientific article published on 27 August 2009

Dual effects of prolonged ACTH stimulation on 4-hydroxyaminoquinoline 1-oxide-induced adrenocortical lesions in rats

scientific article published on 01 July 2000

Effect of fenofibrate on oxidative DNA damage and on gene expression related to cell proliferation and apoptosis in rats

scientific journal article

Effect of rat thyroid proliferative lesion development by intermittent treatment with sulfadimethoxine

scientific article published on 01 September 1995

Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors

scientific article published on 01 June 1995

Effects of caffeine, nicotine, ethanol and sodium selenite on pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine

scientific article published on August 1, 1992

Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice.

scientific article published on October 2010

Electronmicroscopy of sciatic nerves in aging rats with spontaneous radiculoneuropathy

scientific article published on 01 April 1986

Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice.

scientific article published on 26 January 2010

Enhanced liver tumor promotion activity in rats subjected to combined administration of phenobarbital and orphenadrine ⬇️

scientific article published on January 1, 2013

Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone.

scientific article published in January 2012

Enhancement of hepatocarcinogenesis by kojic acid in rat two-stage models after initiation with N-bis(2-hydroxypropyl)nitrosamine or N-diethylnitrosamine.

scientific article

Enhancement of hepatocellular proliferative activity of kojic acid in mice by a simultaneous administration of ascorbic acid.

scientific article

Enhancing effects of beta-estradiol 3-benzoate but not methoxychlor on the promotion/progression stage of chemically-induced mammary carcinogenesis in ovariectomized rats.

scientific article published in July 2002

Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) ⬇️

scientific article published on October 1, 2010

Establishment of an animal model for pulmonary fibrosis in mice using monocrotaline

scientific article published on 01 January 1995

Evaluation of in vivo genotoxic potential of fenofibrate in rats subjected to two-week repeated oral administration.

scientific article published on 3 December 2010

Evaluation of in vivo liver genotoxic potential of Wy-14,643 and piperonyl butoxide in rats subjected to two-week repeated oral administration

scientific journal article

Evaluation of the toxicity of enzymatically decomposed rutin with 13-weeks dietary administration to Wistar rats.

scientific article published in March 2004

Experimental induction of pulmonary fibrosis in Syrian golden hamsters by N-methyl-N-nitrosourethane

scientific article published on 01 October 1994

Experimental induction of uterine adenocarcinoma in rats by estrogen and N-methyl-N-nitrosourea

scientific article published on 01 November 1993

Expression patterns of cell cycle proteins in the livers of rats treated with hepatocarcinogens for 28 days.

scientific article published on 15 February 2013

Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane.

scientific article published on 9 May 2008

Fifty-two week chronic toxicity of enzymatically decomposed rutin in Wistar rats ⬇️

scientific article published on May 31, 2010

Four-day repeated inhalation and recovery study of methyl isocyanate in F344 rats and B6C3F1 mice

scientific article published on 01 October 1987

Further carcinogenicity study on methylmercury chloride in ICR mice

scientific article published on 01 February 1986

Gene expression analyses of the liver in rats treated with oxfendazole

scientific article published on 06 March 2007

Gene expression analysis of urethane-induced lung tumors in ras H2 mice.

scientific article

Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice.

scientific article

Genotoxic potential of quinolone antimicrobials in the in vitro comet assay and micronucleus test.

scientific article published on 27 December 2005

Gingival Rhabdomyosarcoma Accompanied by an Immature Myogenic Population Immunoreactive for α-Smooth Muscle Actin in a Dog ⬇️

scientific article published on December 27, 2012

Global DNA methylation screening of liver in piperonyl butoxide-treated mice in a two-stage hepatocarcinogenesis model.

scientific article published on 19 August 2013

Glycidol Induces Axonopathy by Adult-Stage Exposure and Aberration of Hippocampal Neurogenesis Affecting Late-Stage Differentiation by Developmental Exposure in Rats ⬇️

scientific article published on April 17, 2013

Gonadal toxicity of an ethanol extract of Psoralea corylifolia in a rat 90-day repeated dose study.

scientific article

Hepatocarcinogenic susceptibility of fenofibrate and its possible mechanism of carcinogenicity in a two-stage hepatocarcinogenesis model of rasH2 mice.

scientific article

Hepatocarcinogenic susceptibility of rasH2 mice to troglitazone in a two-stage hepatocarcinogenesis model.

scientific article published on 3 July 2008

Hepatocellular Tumor Induction in Heterozygous p53-Deficient CBA Mice by a 26-Week Dietary Administration of Kojic Acid ⬇️

scientific article published on April 15, 2003

High-grade myofibroblastic sarcoma of inguinal region in a dog.

scientific article published on 9 December 2011

Hormonal influence on carcinogenicity of methylmercury in mice

scientific article published on 01 August 1988

Immunohistochemical and electron microscopic study of meningeal granular cell tumors in rats

scientific article published on 01 July 1987

Immunohistochemical characterization of neuroendocrine differentiation of canine anal sac glandular tumours.

scientific article published on 10 April 2013

Impact of maternal dietary exposure to endocrine-acting chemicals on progesterone receptor expression in microdissected hypothalamic medial preoptic areas of rat offspring.

scientific article published in October 2005

Induction and inhibition of testicular germ cell apoptosis by fluoroacetate in rats

scientific article published on 01 March 2000

Induction of GST-P-positive proliferative lesions facilitating lipid peroxidation with possible involvement of transferrin receptor up-regulation and ceruloplasmin down-regulation from the early stage of liver tumor promotion in rats.

scientific article published on 20 December 2009

Induction of Squamous Cell Carcinomas in the Salivary Glands of Rats by Potassium Iodide ⬇️

scientific article published on February 1, 1998

Induction of ovarian toxicity in a subchronic oral toxicity study of citrinin in female BALB/c mice.

scientific article published in January 2012

Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats.

scientific article published on 2 July 2013

Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.

scientific article published on 19 March 2004

Inhibitory effects of cinnamaldehyde on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung carcinogenesis in rasH2 mice ⬇️

scientific article published on January 10, 2002

Interlaboratory comparison of the CB6F1-Tg rasH2 rapid carcinogenicity testing model.

scientific article

Involvement of PTEN/Akt signaling and oxidative stress on indole-3-carbinol (I3C)-induced hepatocarcinogenesis in rats ⬇️

scientific article published on January 4, 2013

Involvement of PTEN/Akt signaling in capsular invasive carcinomas developed in a rat two-stage thyroid carcinogenesis model after promotion with sulfadimethoxine.

scientific article published on 26 June 2010

Involvement of apoptosis in the rat germ cell degeneration induced by nitrobenzene

scientific article published on 01 April 1998

Involvement of glycogen synthase kinase-3beta signaling and aberrant nucleocytoplasmic localization of retinoblastoma protein in tumor promotion in a rat two-stage thyroid carcinogenesis model.

scientific article

Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats

scientific journal article

Iron lactate induction of pancreatic and endometrial proliferative lesions and a lack of increased tumors in a 104-week carcinogenicity study in F344 rats.

scientific article published on October 2002

Lac color inhibits development of rat thyroid carcinomas through targeting activation of plasma hyaluronan-binding protein

scientific article published on June 19, 2012

Lack of Carcinogenic Sensitivity of the Glandular Stomach in Heterozygous p53 Knockout Mice Given N-Methyl-N-Nitrosourea in their Drinking Water for 26 Weeks

scientific article published on 01 January 2000

Lack of carcinogenicity of cyanoguanidine in F344 rats.

scientific article published in May 1997

Lack of carcinogenicity of ferric chloride in F344 rats

scientific article published on 01 October 1992

Lack of maternal dietary exposure effects of bisphenol A and nonylphenol during the critical period for brain sexual differentiation on the reproductive/endocrine systems in later life ⬇️

scientific article published on October 1, 2003

Lack of modifying effects of eugenol on development of lung proliferative lesions induced by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.

scientific article

Lack of significant effects of genistein on the progression of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.

scientific article published in January 2003

Lack of susceptibility of heterozygous p53-knockout CBA and CIEA mice to phenolphthalein in a 6-month carcinogenicity study.

scientific article

Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study

scientific article published on 01 May 2000

Large amount of vitamin A has no major effects on thyroidal hormone synthesis in two-stage rat thyroid carcinogenesis model using N-bis(2-hydroxypropyl)nitrosamine and thiourea

scientific article published on 01 May 2000

Liver initiation activity of norfloxacin but not nalidixic acid, pipemidic acid, and ciprofloxacin on in vivo short-term liver initiation assay in rats.

scientific article published on 31 March 2006

Liver tumor promoting effect of etofenprox in rats and its possible mechanism of action.

scientific article published on January 2012

Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action ⬇️

scientific article published on January 1, 2012

Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress.

scientific article published on January 2013

Liver tumor promoting effects of fenbendazole in rats

scientific article published on 01 September 1999

Liver tumour-promoting effects of oxfendazole in rats

scientific article published on 01 August 1997

Low-grade myofibroblastic sarcoma of the maxillary region in a dog

scientific article published on 11 October 2011

Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice.

scientific article published on 18 August 2009

Mechanistic study on liver tumor promoting effects of flutamide in rats.

scientific article published on 11 November 2011

Methacarn as a whole brain fixative for gene and protein expression analyses of specific brain regions in rats ⬇️

scientific article published on January 1, 2013

Mice with focal pulmonary fibrosis caused by monocrotaline are insensitive to urethane induction of lung tumorigenesis.

scientific article published in November 1997

Microdissected region-specific gene expression analysis with methacarn-fixed, paraffin-embedded tissues by real-time RT-PCR.

scientific article

Modification of dietary copper levels on the early stage of tumor-promotion with propylthiouracil in a rat two-stage thyroid carcinogenesis model

scientific journal article

Modifying effect of Siraitia grosvenori extract on piperonyl butoxide-promoted hepatocarcinogenesis in rats.

scientific article published in May 2008

Modifying effects of goitrogens on the tumor development in the liver and lung of rats

scientific article published on January 1996

Modifying effects of liver tumor promotion in rats subjected to co-administration of indole-3-carbinol and phenobarbital

scientific article published on February 2014

Molecular expression analysis of beta-naphthoflavone-induced hepatocellular tumors in rats.

scientific article published on 23 April 2009

Morphogenesis of craniopharyngeal derivatives in the neurohypophysis of Fisher 344 rats: abnormally developed epithelial tissues including parotid glands derived from the stomatodeum.

scientific article

Morphological characterization of skin ganglion-like cells in Djungarian hamsters (Phodopus sungorus).

scientific article published in September 2003

Morphological evaluation of cyclophosphamide testicular toxicity in rats using quantitative morphometry of spermatogenic cycle stages

scientific article published on 01 September 1995

Morphometric and immunohistochemical studies on atrophic changes in lympho-hematopoietic organs of rats treated with piperonyl butoxide or subjected to dietary restriction

scientific article published on 01 January 1996

Multiplicity of spontaneous lung tumors in CD-1 mice

scientific article published on 01 May 1989

Murine Schnurri-2controls natural killer cell function and lymphoma development

article

Mutation analysis of vinyl carbamate or urethane induced lung tumors in rasH2 transgenic mice.

scientific article published in April 2003

Mutation and overexpression of the transgene in ethylnitrosourea-induced tumors in mice carrying a human prototype c-Ha-ras gene.

scientific article published in September 2003

Myocardial hamartoma of the right atrium in a dog

scientific article published on 01 November 2002

Neuroendocrine carcinoma of the apocrine glands of the anal sac in a dog

scientific article published on 08 June 2011

No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats

scientific article published on 21 December 2009

No effect of sustained systemic growth retardation on the distribution of Reelin-expressing interneurons in the neuron-producing hippocampal dentate gyrus in rats.

scientific article published on 27 October 2010

Pancreatic carcinosarcoma in a cat.

scientific article published on 18 April 2012

Pathological features of spontaneous and induced tumors in transgenic mice carrying a human prototype c-Ha-ras gene used for six-month carcinogenicity studies.

scientific article published in July 1998

Pinnal oncocytoma in a rat

scientific article published on 01 July 1990

Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice.

scientific article published on 29 January 2008

Point mutations of the c-H-ras gene in spontaneous liver tumors of transgenic mice carrying the human c-H-ras gene.

scientific article published in July 1998

Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice.

scientific article published on 21 March 2006

Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats

scientific journal article

Possible involvement of oxidative stress in piperonyl butoxide induced hepatocarcinogenesis in rats

scientific article published on 06 April 2007

Possible mechanisms underlying the testicular toxicity of oxfendazole in rats.

scientific article

Prediction model of potential hepatocarcinogenicity of rat hepatocarcinogens using a large-scale toxicogenomics database ⬇️

scientific article published on July 19, 2011

Preventive effects of Shichimotsu-koka-to on renal lesions in stroke-prone spontaneously hypertensive rats

scientific article published on 01 September 1998

Preventive effects of calcitriol on the development of capsular invasive carcinomas in a rat two-stage thyroid carcinogenesis model.

scientific article

Primary malignant mixed mesenchymal tumour of the heart in a dog

scientific article published on 01 January 2003

Proliferative lesions in the male reproductive system of F344 rats and B6C3F1 mice: incidence and classification.

scientific article

Promoting effects of 6-mercaptopurine on carcinogenesis in various organs of F344 rats

scientific article published on September 30, 1992

Promoting effects of carminic acid-enriched cochineal extracts on capsular invasive thyroid carcinomas through targeting activation of angiogenesis in rats ⬇️

scientific article published on January 1, 2012

Promoting effects of cigarette smoke on the respiratory tract carcinogenesis of Syrian golden hamsters treated with diethylnitrosamine

scientific article published on April 1, 1992

Promoting effects of kojic acid due to serum TSH elevation resulting from reduced serum thyroid hormone levels on development of thyroid proliferative lesions in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.

scientific article

Protective Effect of <i>Stachybotrys microspora</i> Triprenyl Phenol-7on the Deposition of IgA to the Glomerular Mesangium in Nivalenol-induced IgA Nephropathy Using BALB/c Mice ⬇️

scientific article published on June 1, 2012

Pulmonary fibrosis caused by N-methyl-N-nitrosourethane inhibits lung tumorigenesis by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.

scientific article published in July 1998

Quantitative analysis of neuronal damage induced by tri-ortho-cresyl phosphate in Wistar rats

scientific article published on 01 January 1993

Rapid carcinogenicity testing system with transgenic mice harboring human prototype c-HRAS gene

scientific article published on 01 April 1997

Rapid induction of more malignant tumors by various genotoxic carcinogens in transgenic mice harboring a human prototype c-Ha-ras gene than in control non-transgenic mice

scientific article published on 01 November 1996

Rapid induction of uterine tumors with p53 point mutations in heterozygous p53-deficient CBA mice given a single intraperitoneal administration of N-ethyl-N-nitrosourea

scientific article published on 01 May 2000

Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.

scientific article published on 4 January 2011

Relationship between the development of hepato-renal toxicity and cadmium accumulation in rats given minimum to large amounts of cadmium chloride in the long-term: preliminary study

scientific article published on 01 September 1998

Relationship between the development of pulmonary fibrosis and lung tumors in Syrian golden hamsters induced by N-methyl-N-nitrosourethane

scientific article published on 01 September 1995

Relationship between toxicity and cadmium accumulation in rats given low amounts of cadmium chloride or cadmium-polluted rice for 22 months

scientific article published on 01 December 2001

Reversible aberration of neurogenesis affecting late-stage differentiation in the hippocampal dentate gyrus of rat offspring after maternal exposure to manganese chloride.

scientific article published on 4 May 2012

Reversible aberration of neurogenesis targeting late-stage progenitor cells in the hippocampal dentate gyrus of rat offspring after maternal exposure to acrylamide.

scientific article published on 18 January 2012

Reversible effect of maternal exposure to chlorpyrifos on the intermediate granule cell progenitors in the hippocampal dentate gyrus of rat offspring.

scientific article

Sequential observation of 2,6-dimethylaniline-induced nasal lesions in a rat two-stage nasal carcinogenesis model after initiation with N-bis(2-hydroxypropyl) nitrosamine.

scientific article published in July 2000

Similar distribution changes of GABAergic interneuron subpopulations in contrast to the different impact on neurogenesis between developmental and adult-stage hypothyroidism in the hippocampal dentate gyrus in rats.

scientific article published on 31 March 2012

Smooth muscle hamartoma of the abomasum in a calf

scientific article published on 01 January 2004

Some Characteristics of the Cell Cultures Established from the Tumorous Tissues of Cattle with Bovine Leukosis ⬇️

scientific article published on October 1, 1975

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

scientific article

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice.

scientific article published in January 2012

Spontaneous Malignant Pineocytoma in a Female Wistar Rat ⬇️

scientific article published on June 1, 1991

Spontaneous endocardial schwannoma in a rat

scientific article published on 01 June 1983

Spontaneous histiocytic sarcoma with possible origin from the bone marrow and lymph node in Donryu and F-344 rats

scientific article published on 01 January 1993

Spontaneous tumors in F344/DuCrj rats from 12 control groups of chronic and oncogenicity studies

scientific article published on 01 May 1987

Spontaneous tumors of the meninges in rats

scientific article published on 01 January 1987

Studies on the carcinogenicity of potassium iodide in F344 rats

scientific article published on 01 September 2000

Study on the carcinogenicity of tannic acid in F344 rats.

scientific article published in December 1994

Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats ⬇️

scientific article published on March 29, 2011

Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate andras gene analyses of the induced tumors ⬇️

scientific article published on November 1, 1997

Synergistic effects of phenobarbital and thiourea on proliferative lesions in the rat liver.

scientific article published on June 1994

Testicular toxicity of nitrofurazone causing germ cell apoptosis in rats.

scientific article

The initiation activity of norfloxacin does not result in the induction of hepatocellular tumors in rats.

scientific article published on 10 December 2006

The possible mechanism of enhanced carcinogenesis induced by genotoxic carcinogens in rasH2 mice.

scientific article published on 13 March 2006

The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat

scientific article

The threshold dose for liver tumor promoting effects of dicyclanil in ICR mice.

scientific article published in February 2010

Thirteen-week repeated dose toxicity of Siraitia grosvenori extract in Wistar Hannover (GALAS) rats.

scientific article published on 12 January 2007

Thirteen-week repeated dose toxicity of rice bran glycosphingolipid in Wistar Hannover (GALAS) rats

scientific article published on 01 February 2004

Thirteen-week repeated dose toxicity study of wormwood (Artemisia absinthium) extract in rats

scientific article published on 01 December 2003

Threshold dose dependence in phenobarbital promotion of rat hepatocarcinogenesis initiated by diethylnitrosamine

scientific article published on March 1, 1992

Threshold dose of liver tumor promoting effect of β-naphthoflavone in rats ⬇️

scientific article published on January 1, 2012

Threshold dose of piperonyl butoxide that induces reactive oxygen species-mediated hepatocarcinogenesis in rats

scientific journal article

Thyroid proliferative lesions induced by anti-thyroid drugs in rats are not always accompanied by sustained increases in serum TSH

scientific article published on 01 November 1994

Time course observation of thyroid proliferative lesions and serum TSH levels in rats treated with thiourea after DHPN initiation.

scientific article published in October 1994

Time course of ultrastructural changes and immunoelectron microscopic localization of neurocalcin in motor endplates of the lumbrical muscles of rats given a single administration of 2,5-di(tert-butyl)-1,4-hydroquinone

scientific article published on 01 February 2000

Tissue distribution of cadmium in rats given minimum amounts of cadmium-polluted rice or cadmium chloride for 8 months

scientific article published on 01 October 1999

Toxicity and blood concentrations of xylazine and its metabolite, 2,6-dimethylaniline, in rats after single or continuous oral administrations

scientific article published on 01 May 2000

Transgenic tumor models for carcinogen identification: the heterozygous Trp53-deficient and RasH2 mouse lines.

scientific article published in October 2003

Transient aberration of neuronal development in the hippocampal dentate gyrus after developmental exposure to brominated flame retardants in rats.

scientific article published on 14 March 2012

Transient suppression of late-stage neuronal progenitor cell differentiation in the hippocampal dentate gyrus of rat offspring after maternal exposure to nicotine.

scientific article published on 27 July 2013

Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model.

scientific article published on 17 March 2010

Tumour endothelial marker-1 is expressed in canine Haemangiopericytomas.

scientific article published on 12 March 2013

Twenty-six-week oral toxicity of diheptyl phthalate with special emphasis on its induction of liver proliferative lesions in male F344 rats ⬇️

scientific article published on January 1, 2012

Two-year oral chronic toxicity and carcinogenicity study in rats of diets fumigated with methyl bromide.

scientific article published on February 1990

UDP-GT involvement in the enhancement of cell proliferation in thyroid follicular cell proliferative lesions in rats treated with thiourea and vitamin A.

scientific article published on January 1997

Ultrastructural changes in motor endplates of the lumbrical muscles of rats induced by a microsomal Ca2+ ATPase inhibitor, 2,5-di(tert-butyl)-1,4-hydroquinone

scientific article published on 01 January 1998

Ultrastructure and cell proliferative activities of karyomegalic alveolar epithelial cells in early pulmonary inflammatory lesions of Syrian golden hamsters induced by N-methyl-N-nitrosourethane

scientific article published on 01 September 1996

Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing

scientific article

[13-week subchronic oral toxicity study of ammonium sulfate in rats]

scientific article published on 01 January 1999

[13-week subchronic oral toxicity study of isopropyl p-hydroxybenzoate in F344 rats]

scientific article published on 01 January 1994

[13-week subchronic oral toxicity study of phaffia colour in F344 rats]

scientific article published on 01 January 1997

[A 13-week subchronic oral toxicity study of Perilla extracts in F344 rats]

scientific article published on 01 January 1999

[A 28-day repeated dose toxicity study of nitrobenzene in F344 rats]

scientific article published on 01 January 1994

[A 90-day repeated dose oral toxicity study of magnesium chloride in F344 rats]

scientific article published on 01 January 2000

[Intensity of liver tumor promotion effects in rats given repeated oral administrations of benzimidazole compounds]

scientific article published on 01 January 1996

[Scientific basis in the setting of residue limits for veterinary drugs in food of animal origin taking into account the presence of their metabolites]

scientific article published on 01 January 1993

[Subchronic oral toxicity study of cyanoguanidine in F344 rats]

scientific article published on 01 January 1991

[Toxicity in rats fed diet containing iron lactate for 26 weeks]

scientific article published on 01 January 1995

[Twenty-eight day repeated dose toxicity test of dihepthyl phthalate in F344 rats]

scientific article published on 01 January 1992

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