List of works - David T Humphreys

A heterozygous variant in the human cardiac miR-133 gene, MIR133A2, alters miRNA duplex processing and strand abundance

scientific article

A reexamination of the role of clusterin as a complement regulator.

scientific article published on May 1999

Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins

scientific article published in Journal of Biological Chemistry

Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function

scientific article

Computational analysis, biochemical purification, and detection of tRNA-derived small RNA fragments.

scientific article

Decoding the complex genetic causes of heart diseases using systems biology

scientific article

Effects of Clusterin Overexpression on TNFα- and TGFβ-Mediated Death of L929 Cells ⬇️

article by David Humphreys et al published December 1997 in Biochemistry

Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

scientific article published on 27 December 2013

Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells

scientific article published on 17 June 2013

Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3

scientific article

Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep

scientific article

Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence.

scientific article

Inhibition of translation initiation by a microRNA

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

scientific article

MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

scientific article

Modes of L929 cell death induced by TNF-alpha and other cytotoxic agents.

scientific article

Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors

scientific article published in 2022

Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta

scientific article

Periconceptional undernutrition programs changes in insulin-signaling molecules and microRNAs in skeletal muscle in singleton and twin fetal sheep

scientific article published on 9 January 2014

Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.

scientific article

The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells.

scientific article

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

scientific article

miRspring: a compact standalone research tool for analyzing miRNA-seq data.

scientific article

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells

scientific article

List of works by David T Humphreys

A heterozygous variant in the human cardiac miR-133 gene, MIR133A2, alters miRNA duplex processing and strand abundance

A reexamination of the role of clusterin as a complement regulator.

Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins

Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function

Computational analysis, biochemical purification, and detection of tRNA-derived small RNA fragments.

Decoding the complex genetic causes of heart diseases using systems biology

Effects of Clusterin Overexpression on TNFα- and TGFβ-Mediated Death of L929 Cells ⬇️

Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells

Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3

Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep

Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence.

Inhibition of translation initiation by a microRNA

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

Modes of L929 cell death induced by TNF-alpha and other cytotoxic agents.

Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors

Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta

Periconceptional undernutrition programs changes in insulin-signaling molecules and microRNAs in skeletal muscle in singleton and twin fetal sheep

Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.

The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells.

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

miRspring: a compact standalone research tool for analyzing miRNA-seq data.

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells