List of works - Bogdan Pasaniuc

A Bayesian Framework for Multiple Trait Colo-calization from Summary Association Statistics

scientific article published on 19 March 2018

A Genetic Population Isolate in The Netherlands Showing Extensive Haplotype Sharing and Long Regions of Homozygosity

scientific article

A multi-stage genome-wide association study of uterine fibroids in African Americans

scientific article

A multivariate Bernoulli model to predict DNaseI hypersensitivity status from haplotype data

scientific article

A spatial haplotype copying model with applications to genotype imputation

scientific article published on 19 December 2014

A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants

scientific article published on 01 May 2019

Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture

scientific article published on 29 July 2019

Accurate estimation of expression levels of homologous genes in RNA-seq experiments.

scientific article published in March 2011

Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas

scientific article published on 6 January 2012

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

scientific article

Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation

scientific article published on 9 April 2013

Analysis of case-control association studies with known risk variants

scientific article

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

scientific article published on 7 April 2016

Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

Colocalization of GWAS and eQTL Signals Detects Target Genes

scientific article

Combining effects from rare and common genetic variants in an exome-wide association study of sequence data

scientific article

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

scientific article

Credible learning of hydroxychloroquine and dexamethasone effects on COVID-19 mortality outside of randomized trials ⬇️

scientific article published on 08 December 2020

Dissecting the genetics of complex traits using summary association statistics ⬇️

scientific article

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

scientific article published in 2022

Enhanced localization of genetic samples through linkage-disequilibrium correction

scientific article (publication date: 6 June 2013)

Enhanced methods for local ancestry assignment in sequenced admixed individuals

scientific article

Enhanced methods to detect haplotypic effects on gene expression

scientific article

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium

scientific article

Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans

scientific article published on 4 October 2017

Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits

scientific article published on 21 October 2021

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

scientific article published on 20 May 2012

Fast and accurate imputation of summary statistics enhances evidence of functional enrichment

scientific article

Fast and accurate inference of local ancestry in Latino populations

scientific article

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

scientific article

Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection

scientific article

Genotype error detection using Hidden Markov Models of haplotype diversity.

scientific article published in November 2008

Genotyping common and rare variation using overlapping pool sequencing ⬇️

scientific article published on July 28, 2011

Highly Scalable Genotype Phasing by Entropy Minimization

scientific article published on 01 January 2006

Highly scalable genotype phasing by entropy minimization.

scientific article

IBD genetics: focus on (dys) regulation in immune cells and the epithelium.

scientific article

Identification of causal genes for complex traits

scientific article

Identifying causal variants at loci with multiple signals of association

scientific article

Improved methods for multi-trait fine mapping of pleiotropic risk loci

scientific article published on 22 September 2016

Inference of locus-specific ancestry in closely related populations

scientific article published on June 2009

Informed conditioning on clinical covariates increases power in case-control association studies

scientific article published on 8 November 2012

Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal

scientific article published on September 2011

Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits

scientific article

Integrating functional data to prioritize causal variants in statistical fine-mapping studies

scientific article

Integrative approaches for large-scale transcriptome-wide association studies

scientific article published on 8 February 2016

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

scientific article

Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders

scientific article published on 22 April 2015

Leveraging genetic variability across populations for the identification of causal variants.

scientific article

Leveraging local ancestry to detect gene-gene interactions in genome-wide data

scientific article

Leveraging population admixture to characterize the heritability of complex traits

scientific article

Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data

scientific article

Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits

scientific article published in November 2017

Methods for fine-mapping with chromatin and expression data.

scientific article published on 26 February 2018

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

scientific article

New approaches to disease mapping in admixed populations

scientific article (publication date: 28 June 2011)

Opportunities and challenges for transcriptome-wide association studies

scientific article published on 29 March 2019

Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes

scientific article published in 2022

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

scientific article

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

scientific article published in September 2022

Prior diagnoses and medications as risk factors for COVID-19 in a Los Angeles Health System

scientific article published on 04 July 2020

Probabilistic fine-mapping of transcriptome-wide association studies

scientific article published on 29 March 2019

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24

scientific article published on 27 January 2016

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quantifying missing heritability at known GWAS loci

scientific article

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Spatial localization of recent ancestors for admixed individuals

scientific article

The contribution of rare variation to prostate cancer heritability

scientific article

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

scientific article published on 01 March 2020

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

article

Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits

scientific article

Using population admixture to help complete maps of the human genome

scientific article published on 24 February 2013

Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk

scientific article published on 24 November 2015

Widespread Allelic Heterogeneity in Complex Traits

scientific article published on May 2017

List of works by Bogdan Pasaniuc

A Bayesian Framework for Multiple Trait Colo-calization from Summary Association Statistics

A Genetic Population Isolate in The Netherlands Showing Extensive Haplotype Sharing and Long Regions of Homozygosity

A multi-stage genome-wide association study of uterine fibroids in African Americans

A multivariate Bernoulli model to predict DNaseI hypersensitivity status from haplotype data

A spatial haplotype copying model with applications to genotype imputation

A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants

Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture

Accurate estimation of expression levels of homologous genes in RNA-seq experiments.

Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation

Analysis of case-control association studies with known risk variants

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

Colocalization of GWAS and eQTL Signals Detects Target Genes

Combining effects from rare and common genetic variants in an exome-wide association study of sequence data

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

Credible learning of hydroxychloroquine and dexamethasone effects on COVID-19 mortality outside of randomized trials ⬇️

Dissecting the genetics of complex traits using summary association statistics ⬇️

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

Enhanced localization of genetic samples through linkage-disequilibrium correction

Enhanced methods for local ancestry assignment in sequenced admixed individuals

Enhanced methods to detect haplotypic effects on gene expression

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium

Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans

Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Fast and accurate imputation of summary statistics enhances evidence of functional enrichment

Fast and accurate inference of local ancestry in Latino populations

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection

Genotype error detection using Hidden Markov Models of haplotype diversity.

Genotyping common and rare variation using overlapping pool sequencing ⬇️

Highly Scalable Genotype Phasing by Entropy Minimization

Highly scalable genotype phasing by entropy minimization.

IBD genetics: focus on (dys) regulation in immune cells and the epithelium.

Identification of causal genes for complex traits

Identifying causal variants at loci with multiple signals of association

Improved methods for multi-trait fine mapping of pleiotropic risk loci

Inference of locus-specific ancestry in closely related populations

Informed conditioning on clinical covariates increases power in case-control association studies

Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal

Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits

Integrating functional data to prioritize causal variants in statistical fine-mapping studies

Integrative approaches for large-scale transcriptome-wide association studies

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders

Leveraging genetic variability across populations for the identification of causal variants.

Leveraging local ancestry to detect gene-gene interactions in genome-wide data

Leveraging population admixture to characterize the heritability of complex traits

Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data

Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits

Methods for fine-mapping with chromatin and expression data.

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

New approaches to disease mapping in admixed populations

Opportunities and challenges for transcriptome-wide association studies

Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

Prior diagnoses and medications as risk factors for COVID-19 in a Los Angeles Health System

Probabilistic fine-mapping of transcriptome-wide association studies

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

Quantifying missing heritability at known GWAS loci

Shared heritability and functional enrichment across six solid cancers

Shared heritability and functional enrichment across six solid cancers

Spatial localization of recent ancestors for admixed individuals

The contribution of rare variation to prostate cancer heritability

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits

Using population admixture to help complete maps of the human genome

Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk

Widespread Allelic Heterogeneity in Complex Traits