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List of works by Pau Sancho-Bru

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Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II.

scientific article
Human hepatic stellate cells show features of antigen-presenting cells and stimulate lymphocyte proliferation

scientific article published on October 2003
Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis

scientific article
The biliary epithelium gives rise to liver progenitor cells

scientific article published on 21 August 2014
Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis.

scientific article published on 23 April 2012
Liver fibrogenesis: a new role for the renin-angiotensin system

scientific article
Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis.

scientific article
Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C

scientific article published on 23 July 2009
Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells

scientific article published on December 2006
Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity.

scientific article published on 20 December 2006
Stem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside?

scientific article published on 17 December 2008
Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans

scientific article published in March 2010
CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis

scientific article
Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis.

scientific article published on 19 August 2013
Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats

Directed differentiation of murine-induced pluripotent stem cells to functional hepatocyte-like cells

Genomic and functional characterization of stellate cells isolated from human cirrhotic livers

scientific article published in August 2005
Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells

scientific article
Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

scientific article
Atorvastatin attenuates angiotensin II-induced inflammatory actions in the liver

scientific article
Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells

scientific article published on 22 June 2015
Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells

scientific article
Novel hyperactive transposons for genetic modification of induced pluripotent and adult stem cells: a nonviral paradigm for coaxed differentiation.

scientific article published on October 2010
Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis

scientific article
Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.

scientific article published on 10 May 2016
Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication

scientific article
Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells

scientific article
A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis.

scientific article published on 24 January 2017
Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells

scientific article
In vitro reversion of activated primary human hepatic stellate cells

scientific article published on 6 August 2015
Human myofibroblastic hepatic stellate cells express Ca(2+)-activated K(+) channels that modulate the effects of endothelin-1 and nitric oxide

scientific article published in December 2001
Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells

scientific article
VSL#3 probiotic treatment decreases bacterial translocation in rats with carbon tetrachloride-induced cirrhosis.

scientific article published on 12 May 2014
Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury

scientific article published on 26 September 2007
Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

scientific article published on 23 February 2018
Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors

scientific article published on 24 February 2011
Expression of microRNA-155 in inflammatory cells modulates liver injury

scientific article published on 8 February 2018
LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis

scientific article published on 18 October 2016
Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury.

scientific article published on 19 April 2017
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

scientific article published on 16 July 2019
Human hepatic stellate cells secrete adrenomedullin: potential autocrine factor in the regulation of cell contractility.

scientific article
Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients

scientific article
Differentiation of rat multipotent adult progenitor cells to functional hepatocyte-like cells by mimicking embryonic liver development

scientific article published on 24 June 2010
A small population of liver endothelial cells undergoes endothelial-to-mesenchymal transition in response to chronic liver injury.

scientific article published on 10 August 2017
Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis

scientific article published on 21 December 2015
Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes

scientific article published on 12 May 2017
Culture of mouse embryonic stem cells with serum but without exogenous growth factors is sufficient to generate functional hepatocyte-like cells

scientific article
CCL2: a link between hepatic inflammation, fibrosis and angiogenesis?

scientific article published on 2 April 2014
Mesenchymal stromal cells for immunomodulatory cell therapy in liver transplantation: One step at a time.

scientific article published on 20 April 2017
Assessment of Liver Fibrotic Insults In Vitro.

scientific article

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