List of works by Pau Sancho-Bru

A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis.

scientific article published on 24 January 2017

A small population of liver endothelial cells undergoes endothelial-to-mesenchymal transition in response to chronic liver injury.

scientific article published on 10 August 2017

Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II.

scientific article

Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes

scientific article published on 12 May 2017

Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

scientific article published on 23 February 2018

Assessment of Liver Fibrotic Insults In Vitro.

scientific article

Atorvastatin attenuates angiotensin II-induced inflammatory actions in the liver

scientific article

Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury

scientific article published on 26 September 2007

CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis

scientific article

CCL2: a link between hepatic inflammation, fibrosis and angiogenesis?

scientific article published on 2 April 2014

Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis

scientific article published on 21 December 2015

Culture of mouse embryonic stem cells with serum but without exogenous growth factors is sufficient to generate functional hepatocyte-like cells

scientific article

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

scientific article published on 16 July 2019

Differentiation of rat multipotent adult progenitor cells to functional hepatocyte-like cells by mimicking embryonic liver development

scientific article published on 24 June 2010

Directed differentiation of murine-induced pluripotent stem cells to functional hepatocyte-like cells

Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

scientific article published in 2022

Ductular Reaction Cells Display an Inflammatory Profile and Recruit Neutrophils in Alcoholic Hepatitis

scientific article published on 12 March 2019

Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C

scientific article published on 23 July 2009

Expression of microRNA-155 in inflammatory cells modulates liver injury

scientific article published on 8 February 2018

Fermented milk containing Lactobacillus paracasei subsp. paracasei CNCM I-1518 reduces bacterial translocation in rats treated with carbon tetrachloride

scientific article published on 03 April 2017

Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

scientific article

Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells

scientific article

Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells

scientific article

Genomic and functional characterization of stellate cells isolated from human cirrhotic livers

scientific article

Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans

scientific article published in March 2010

Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity.

scientific article published on 20 December 2006

Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells

scientific article

Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients

scientific article

Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis.

scientific article published on 19 August 2013

Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells

scientific article

Human hepatic stellate cells secrete adrenomedullin: potential autocrine factor in the regulation of cell contractility.

scientific article

Human hepatic stellate cells show features of antigen-presenting cells and stimulate lymphocyte proliferation

scientific article published on October 2003

Human myofibroblastic hepatic stellate cells express Ca(2+)-activated K(+) channels that modulate the effects of endothelin-1 and nitric oxide

scientific article published in December 2001

In vitro reversion of activated primary human hepatic stellate cells

scientific article published on 6 August 2015

Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors

scientific article published on 24 February 2011

Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells

scientific article published on 22 June 2015

Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.

scientific article published on 10 May 2016

Kinase analysis in alcoholic hepatitis identifies p90RSK as a potential mediator of liver fibrogenesis

scientific article published on 4 February 2015

LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis

scientific article published on 18 October 2016

Liver fibrogenesis: a new role for the renin-angiotensin system

scientific article

Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis.

scientific article published on 23 April 2012

Mesenchymal stromal cells for immunomodulatory cell therapy in liver transplantation: One step at a time.

scientific article published on 20 April 2017

Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis

scientific article

Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells.

scientific article

Novel hyperactive transposons for genetic modification of induced pluripotent and adult stem cells: a nonviral paradigm for coaxed differentiation.

scientific article published on October 2010

PD-L1 is overexpressed in liver macrophages in chronic liver diseases and its blockade improves the antibacterial activity against infections

scientific article published on 20 November 2020

Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury.

scientific article published on 19 April 2017

Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats

Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells

scientific article published on December 2006

Stem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside?

scientific article published on 17 December 2008

Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication

scientific article

Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis.

scientific article

Targeting the renin-angiotensin system in liver fibrosis.

scientific article published on 31 May 2016

The biliary epithelium gives rise to liver progenitor cells

scientific article published on 21 August 2014

Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis

scientific article

VSL#3 probiotic treatment decreases bacterial translocation in rats with carbon tetrachloride-induced cirrhosis.

scientific article published on 12 May 2014

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