List of works - Tsutomu Sasaki

A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice.

scientific article

A critical role of fatty acid binding protein 4 and 5 (FABP4/5) in the systemic response to fasting

scientific article published on 14 November 2013

ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription

scientific article published on 20 October 2013

Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity

scientific article (publication date: 2015)

Comparison of gene expression profiles between frozen original meningiomas and primary cultures of the meningiomas by GeneChip.

scientific article

Control of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-Serine

scientific article

DeltaNp53 or p44: priming the p53 pump.

scientific article

Dnmt3a in Sim1 neurons is necessary for normal energy homeostasis

scientific article

Ectopic osteogenesis using adenoviral bone morphogenetic protein (BMP)-4 and BMP-6 gene transfer.

scientific article

Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice.

scientific article published on 12 April 2014

Expanding frontiers in weight-control research explored by young investigators

scientific article

Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis

scientific article

Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice.

scientific article published on 29 December 2013

Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor.

scientific article

Intraperitoneal injection of d-serine inhibits high-fat diet intake and preference in male mice.

scientific article

Major vault protein/lung resistance-related protein (MVP/LRP) expression in nervous system tumors.

scientific article

Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates.

scientific article published on 30 August 2013

Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue

scientific article published on 2 April 2015

N-methyl-d-aspartate receptor coagonist d-serine suppresses intake of high-preference food

scientific article published on 8 July 2015

Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis.

scientific article

Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns

scientific article published on 20 October 2017

Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice

scientific article published in Nature Communications

Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity

scientific article published on 11 August 2017

Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat.

scientific article

Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance

scientific article published on 14 June 2018

Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice.

scientific article

Phosphorylation regulates SIRT1 function.

scientific article

Protection against high-fat diet-induced obesity in Helz2-deficient male mice due to enhanced expression of hepatic leptin receptor.

scientific article published on 8 July 2014

Roles of FoxO1 and Sirt1 in the central regulation of food intake ⬇️

scientific article published on October 30, 2010

SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels

scientific article published on 27 October 2018

Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice

scientific article

microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity

scientific article published on 16 February 2021

List of works by Tsutomu Sasaki

A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice.

A critical role of fatty acid binding protein 4 and 5 (FABP4/5) in the systemic response to fasting

ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription

Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity

Comparison of gene expression profiles between frozen original meningiomas and primary cultures of the meningiomas by GeneChip.

Control of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-Serine

DeltaNp53 or p44: priming the p53 pump.

Dnmt3a in Sim1 neurons is necessary for normal energy homeostasis

Ectopic osteogenesis using adenoviral bone morphogenetic protein (BMP)-4 and BMP-6 gene transfer.

Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice.

Expanding frontiers in weight-control research explored by young investigators

Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis

Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice.

Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor.

Intraperitoneal injection of d-serine inhibits high-fat diet intake and preference in male mice.

Major vault protein/lung resistance-related protein (MVP/LRP) expression in nervous system tumors.

Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates.

Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue

N-methyl-d-aspartate receptor coagonist d-serine suppresses intake of high-preference food

Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis.

Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns

Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice

Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity

Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat.

Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance

Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice.

Phosphorylation regulates SIRT1 function.

Protection against high-fat diet-induced obesity in Helz2-deficient male mice due to enhanced expression of hepatic leptin receptor.

Roles of FoxO1 and Sirt1 in the central regulation of food intake ⬇️

SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels

Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice

microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity