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List of works by Peter Mertens

"Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence

scientific article published on 28 April 2020

A European field strain of bluetongue virus derived from two parental vaccine strains by genome segment reassortment.

scientific article published on 29 July 2008

A Review of Knowledge Gaps and Tools for Orbivirus Research.

scientific article published on June 2015

A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells

scientific article

A comparison of six cypovirus isolates by cross-hybridisation of their dsRNA genome segments.

scientific article published on January 1999

A competitive ELISA for the detection of group-specific antibody to equine encephalosis virus.

scientific article published on 31 March 2011

A duplex RT-PCR assay for detection of genome segment 7 (VP7 gene) from 24 BTV serotypes.

scientific article

A modified vaccinia Ankara virus (MVA) vaccine expressing African horse sickness virus (AHSV) VP2 protects against AHSV challenge in an IFNAR -/- mouse model.

scientific article

A potential overwintering mechanism for bluetongue virus--recent findings.

scientific article published in October 2004

A quantitative real-time reverse transcription PCR (qRT-PCR) assay to detect genome segment 9 of all 26 bluetongue virus serotypes.

scientific article published on 5 December 2014

Adaptive strategies of African horse sickness virus to facilitate vector transmission

scientific article (publication date: 2009)

African horse sickness in The Gambia: circulation of a live-attenuated vaccine-derived strain

scientific article published on May 9, 2011

African horse sickness outbreaks caused by multiple virus types in Ethiopia.

scientific article published on 22 October 2012

African horsesickness virus VP7 sub-unit vaccine protects mice against a lethal, heterologous serotype challenge

scientific article published on July 1, 1997

Analysis and phylogenetic comparisons of full-length VP2 genes of the 24 bluetongue virus serotypes.

scientific article published on February 2007

Analysis of the terminal sequences of the genome segments of four orbiviruses

scientific article published on 01 January 1985

Antiserum from mice vaccinated with modified vaccinia Ankara virus expressing African horse sickness virus (AHSV) VP2 provides protection when it is administered 48h before, or 48h after challenge.

scientific article published on 30 January 2015

Assignment of the genome segments of bluetongue virus type 1 to the proteins which they encode.

scientific article published in May 1984

Biolistic transfection of human embryonic kidney (HEK) 293 cells.

scientific article

Biological and molecular studies of a cypovirus from the black fly Simulium ubiquitum (Diptera: Simuliidae).

scientific article published on 16 January 2007

Bluetongue in Europe and the Mediterranean Basin: history of occurrence prior to 2006.

scientific article

Bluetongue virus infection induces aberrant mitosis in mammalian cells

scientific article published on 28 October 2013

Bluetongue virus replication, molecular and structural biology.

scientific article published in October 2004

Bluetongue virus serotype 8-associated hydranencephaly in two calves in south-eastern England.

scientific article published in August 2010

Capping and methylation of mRNA by purified recombinant VP4 protein of bluetongue virus.

scientific article published on November 1998

Characterisation and partial sequence analysis of two novel cypoviruses isolated from the winter moth Operophtera brumata (Lepidoptera: Geometridae).

scientific article published on 2 June 2007

Characterization of sheep pox virus vaccine for cattle against lumpy skin disease virus

scientific article published on 25 June 2014

Comparison of cellular and humoral immunoassays for the assessment of summer eczema in horses.

scientific article published on 9 November 2007

Comparison of the virus-associated polymerases of cytoplasmic polyhedrosis virus types 1 and 2.

scientific article published in January 1984

Competitive ELISA for the detection of antibodies against epizootic haemorrhagic disease of deer virus.

scientific article published on November 1995

Complete genome sequence analysis of a reference strain of bluetongue virus serotype 16

scientific article published on September 2012

Complete genome sequence of an isolate of bluetongue virus serotype 2, demonstrating circulation of a Western topotype in southern India.

scientific article published on May 2012

Complete nucleotide sequence of Middelburg virus, isolated from the spleen of a horse with severe clinical disease in Zimbabwe

scientific article published in November 2007

Completion of the sequence analysis and comparisons of genome segment 2 (encoding outer capsid protein VP2) from representative isolates of the 24 bluetongue virus serotypes.

scientific article published on October 2004

Design of primers and use of RT-PCR assays for typing European bluetongue virus isolates: differentiation of field and vaccine strains.

scientific article

Detection and characterisation of three novel species of reovirus (Reoviridae), isolated from geographically separate populations of the winter moth Operophtera brumata (Lepidoptera: Geometridae) on Orkney.

scientific article published on 18 January 2006

Determinants of bluetongue virus virulence in murine models of disease

scientific article published on 24 August 2011

Development and Evaluation of Real Time RT-PCR Assays for Detection and Typing of Bluetongue Virus.

scientific article

Development of Real-Time RT-PCR Assays for Detection and Typing of Epizootic Haemorrhagic Disease Virus.

scientific article

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Assay for the Rapid Detection of African Horse Sickness Virus.

scientific article published on 2 August 2016

Development of the polymerase chain reaction for the detection of bluetongue virus in tissue samples.

scientific article published on October 1990

Differential diagnosis of bluetongue virus using a reverse transcriptase-polymerase chain reaction for genome segment 7.

scientific article published in October 2004

Drosophila melanogaster as a model organism for bluetongue virus replication and tropism

scientific article

Enhanced infectivity of modified bluetongue virus particles for two insect cell lines and for two Culicoides vector species.

scientific article

Epizootic haemorrhagic disease virus type 7 infection in cattle in Israel.

scientific article published in January 2008

Equine encephalosis virus: evidence for circulation beyond southern Africa.

scientific article

Evaluation of adaptive immune responses and heterologous protection induced by inactivated bluetongue virus vaccines.

scientific article published on 11 December 2014

Evidence of seroconversion to SBV in camelids

article

Expression and secretion of Bluetongue virus serotype 8 (BTV-8)VP2 outer capsid protein by mammalian cells.

scientific article published on 10 August 2010

Expression of the outer capsid protein, VP2, from a full length cDNA clone of genome segment 2 of bluetongue serotype 1 from South Africa, using both Sp6 and vaccinia expression systems and a comparison of the nucleic acid sequence of this segment w

scientific article published on March 1990

Full genome characterization of the culicoides-borne marsupial orbiviruses: Wallal virus, Mudjinbarry virus and Warrego viruses.

scientific article

Full genome sequence of a Western reference strain of bluetongue virus serotype 16 from Nigeria

scientific article published on 19 September 2013

Full genome sequence of bluetongue virus serotype 1 from India.

scientific article published on April 2012

Full genome sequencing and genetic characterization of Eubenangee viruses identify Pata virus as a distinct species within the genus Orbivirus.

scientific article

Full-Genome Sequencing as a Basis for Molecular Epidemiology Studies of Bluetongue Virus in India.

scientific article

Generation of virus like particles for epizootic hemorrhagic disease virus.

scientific article published on 31 May 2016

Genetic and phylogenetic analysis of the non-structural proteins NS1, NS2 and NS3 of epizootic haemorrhagic disease virus (EHDV).

scientific article published on 7 August 2009

Genetic and phylogenetic analysis of the outer-coat proteins VP2 and VP5 of epizootic haemorrhagic disease virus (EHDV): comparison of genetic and serological data to characterise the EHDV serogroup.

scientific article

Genetic characterization of the tick-borne orbiviruses.

scientific article published on 28 April 2015

Genome Sequence of Bluetongue Virus Type 2 from India: Evidence for Reassortment between Outer Capsid Protein Genes.

scientific article

Genome Sequence of Bluetongue virus Serotype 17 Isolated in Brazil in 2014.

scientific article

Genome Sequence of a Reassortant Strain of Bluetongue Virus Serotype 23 from Western India

scientific article published on June 1, 2012

Identification of a bluetongue virus serotype 1-specific ovine helper T-cell determinant in outer capsid protein VP2

scientific article published on July 1, 1990

Identification of the Genome Segments of Bluetongue Virus Serotype 26 (Isolate KUW2010/02) that Restrict Replication in a Culicoides sonorensis Cell Line (KC Cells).

scientific article published on 18 February 2016

Immunisation with bacterial expressed VP2 and VP5 of bluetongue virus (BTV) protect α/β interferon-receptor knock-out (IFNAR(-/-)) mice from homologous lethal challenge

scientific article published on 2 June 2014

Immunization of knock-out α/β interferon receptor mice against lethal bluetongue infection with a BoHV-4-based vector expressing BTV-8 VP2 antigen.

scientific article published on 12 February 2011

In vitro RNA Synthesis by Infectious Pancreatic Necrosis Virus-associated RNA Polymerase

scientific article published on March 1, 1982

Induction of antibody responses to African horse sickness virus (AHSV) in ponies after vaccination with recombinant modified vaccinia Ankara (MVA).

scientific article

Isolates of Liao Ning Virus from Wild-Caught Mosquitoes in the Xinjiang Province of China in 2005

scientific article published on May 23, 2012

Isolation and full-length sequence analysis of Armigeres subalbatus totivirus, the first totivirus isolate from mosquitoes representing a proposed novel genus (Artivirus) of the family Totiviridae.

scientific article published on 11 August 2010

Isolation and phylogenetic grouping of equine encephalosis virus in Israel

scientific article published in October 2011

Isolation of Bluetongue Virus 24 from India - An Exotic Serotype to Australasia.

scientific article published on 30 May 2016

Measurement of the infection and dissemination of bluetongue virus in culicoides biting midges using a semi-quantitative rt-PCR assay and isolation of infectious virus

scientific article

Molecular analysis of the NS3/NS3A gene of Bluetongue virus isolates from the 1979 and 1998-2001 epizootics in Greece and their segregation into two distinct groups.

scientific article published on July 2005

Molecular and biological characterization of a Cypovirus from the mosquito Culex restuans.

scientific article published on 22 December 2005

Molecular epidemiology of bluetongue virus serotype 1 isolated in 2006 from Algeria

scientific article published on 11 November 2010

Molecular epidemiology of bluetongue virus serotype 4 isolated in the Mediterranean Basin between 1979 and 2004.

scientific article published on 5 February 2007

Molecular epidemiology of bluetongue viruses from disease outbreaks in the Mediterranean Basin

scientific article published on 01 October 2004

Monoclonal antibody based competitive ELISA for the detection of antibodies against epizootic haemorrhagic disease of deer virus.

scientific article published on April 1996

Morphological and molecular characterization of a Cypovirus (Reoviridae) from the mosquito Uranotaenia sapphirina (Diptera: Culicidae)

scientific article published on August 2005

Mortality and case fatality during the recurrence of BTV-8 in northern Europe in 2007

scientific article published on 01 October 2007

Multiple serotypes of bluetongue virus in sheep and cattle, Israel

scientific article published on December 2010

Novel Bluetongue Virus Serotype from Kuwait

scientific article published on May 1, 2011

Phylogenetic analysis of African horse sickness virus segment 10: sequence variation, virulence characteristics and cell exit.

scientific article published on January 1998

Phylogenetic analysis of bluetongue virus genome segment 6 (encoding VP5) from different serotypes.

scientific article published on October 2004

Proteolytic cleavage of VP2, an outer capsid protein of African horse sickness virus, by species-specific serum proteases enhances infectivity in Culicoides.

scientific article

Purification and characterization of viral dsRNA genome profiles by crosshybridization

scientific article published on 01 January 1998

Rapid cDNA synthesis and sequencing techniques for the genetic study of bluetongue and other dsRNA viruses

article

Real time RT-PCR assays for detection and typing of African horse sickness virus

scientific article

Reply to “Intercontinental Movement of Bluetongue Virus and Potential Consequences to Trade”.

scientific article published in August 2012

Reverse transcription loop-mediated isothermal amplification assays for rapid identification of eastern and western strains of bluetongue virus in India

scientific article published on 4 April 2016

S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses

scientific article published on June 1, 1978

Saliva proteins of vector Culicoides modify structure and infectivity of bluetongue virus particles.

scientific article

Sequence analysis of a reovirus isolated from the winter moth Operophtera brumata (Lepidoptera: Geometridae) and its parasitoid wasp Phobocampe tempestiva (Hymenoptera: Ichneumonidae).

scientific article

Sequence analysis of bluetongue virus serotype 8 from the Netherlands 2006 and comparison to other European strains.

scientific article published on August 2008

Sequence of genome segment 9 of bluetongue virus (serotype 1, South Africa) and expression analysis demonstrating that different forms of VP6 are derived from initiation of protein synthesis at two distinct sites

scientific article published on November 1, 1992

Serosurveillance of orbiviruses in wild cervids from Spain.

scientific article published in May 2013

Simian rotaviruses possess divergent gene constellations that originated from interspecies transmission and reassortment.

scientific article published on 25 November 2009

Synthesis of recombinant baculoviruses expressing the outer capsid protein VP2 of five BTV serotypes and the induction of neutralizing antibodies to homologous and heterologous BTV serotypes.

scientific article published on February 1994

Taxonomy of African horse sickness viruses.

scientific article

The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells

scientific article published on 22 December 2020

The atomic structure of the bluetongue virus core

scientific article

The bluetongue virus core: a nano-scale transcription machine.

scientific article published on April 2004

The combination of abundance and infection rates of Culicoides sonorensis estimates risk of subsequent bluetongue virus infection of sentinel cattle on California dairy farms.

scientific article published on 8 January 2012

The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.

scientific article

The effects of S-adenosyl methionine (AdoMet) and its analogues on the control of transcription and translation in vitro of the mRNA products of two cytoplasmic polyhedrosis viruses.

scientific article published in November 1983

The evolution of two homologues of the core protein VP6 of epizootic haemorrhagic disease virus (EHDV), which correspond to the geographical origin of the virus.

scientific article published on 15 October 2009

The expressed VP4 protein of bluetongue virus binds GTP and is the candidate guanylyl transferase of the virus

scientific article published on August 1, 1992

The genome sequence of a reassortant bluetongue virus serotype 3 from India.

scientific article

The genome sequence of bluetongue virus type 10 from India: evidence for circulation of a western topotype vaccine strain.

scientific article published on May 2012

The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography.

scientific article published in May 1999

The structure of a cypovirus and the functional organization of dsRNA viruses.

scientific article

Translocation portals for the substrates and products of a viral transcription complex: the bluetongue virus core.

scientific article

Transmission pathways of foot-and-mouth disease virus in the United Kingdom in 2007

scientific article

Transplacental transmission of bluetongue virus 8 in cattle, UK.

scientific article

Umatilla Virus Genome Sequencing and Phylogenetic Analysis: Identification of Stretch Lagoon Orbivirus as a New Member of the Umatilla virus Species

scientific article published on August 29, 2011

Using shared needles for subcutaneous inoculation can transmit bluetongue virus mechanically between ruminant hosts

scientific article

VP7 from African horse sickness virus serotype 9 protects mice against a lethal, heterologous serotype challenge.

scientific article

Vaccination of horses with a recombinant modified vaccinia Ankara virus (MVA) expressing African horse sickness (AHS) virus major capsid protein VP2 provides complete clinical protection against challenge

scientific article

Vaccination of mice with a modified Vaccinia Ankara (MVA) virus expressing the African horse sickness virus (AHSV) capsid protein VP2 induces virus neutralising antibodies that confer protection against AHSV upon passive immunisation

scientific article published on 12 December 2013

Viraemia and clinical disease in Dorset Poll sheep following vaccination with live attenuated bluetongue virus vaccines serotypes 16 and 4.

scientific article published on 4 November 2009

Virus and host factors affecting the clinical outcome of bluetongue virus infection.

scientific article

Widespread Reassortment Shapes the Evolution and Epidemiology of Bluetongue Virus following European Invasion

scientific article published on 7 August 2015