List of works - Snaevar Sigurdsson

A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

scientific article

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE.

scientific article

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

scientific article published on 25 June 2008

An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases

article

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

article

Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia

scientific article published on 24 June 2019

Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder

scientific article

Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24

scientific article (publication date: February 2014)

Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood

scientific article published on 30 October 2019

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

article by Snaevar Sigurdsson et al published 6 December 2007 in Human Molecular Genetics

Copy number expansion of the STX17 duplication in melanoma tissue from Grey horses

scientific article

Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability.

scientific article published on 7 August 2017

Fine-mapping and mutation analysis of TRPM1: a candidate gene for leopard complex (LP) spotting and congenital stationary night blindness in horses

article

Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations

scientific article published on 8 August 2017

Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

scientific article published on February 2010

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

scientific article

Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4.

scientific article published on 23 June 2012

Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping

scientific article

Multiplex SNP genotyping in pooled DNA samples by a four-colour microarray system

scientific article

Mutation discovery in mice by whole exome sequencing

scientific article published on 14 September 2011

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

scientific article

Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery

scientific article

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

scientific article

Quantitative evaluation by minisequencing and microarrays reveals accurate multiplexed SNP genotyping of whole genome amplified DNA.

scientific article published on November 2003

Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis

scientific article

Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant

scientific article

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

scholarly article

Variants of the Interferon Regulatory Factor 5 Gene Regulate Expression of IRF5 mRNA in Atherosclerotic Tissue But Are Not Associated With Myocardial Infarction

article

List of works by Snaevar Sigurdsson

A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE.

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia

Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder

Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24

Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

Copy number expansion of the STX17 duplication in melanoma tissue from Grey horses

Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability.

Fine-mapping and mutation analysis of TRPM1: a candidate gene for leopard complex (LP) spotting and congenital stationary night blindness in horses

Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations

Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4.

Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping

Multiplex SNP genotyping in pooled DNA samples by a four-colour microarray system

Mutation discovery in mice by whole exome sequencing

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

Quantitative evaluation by minisequencing and microarrays reveals accurate multiplexed SNP genotyping of whole genome amplified DNA.

Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis

Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

Variants of the Interferon Regulatory Factor 5 Gene Regulate Expression of IRF5 mRNA in Atherosclerotic Tissue But Are Not Associated With Myocardial Infarction