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List of works by Gunasegaran Karupiah

A natural genetic variant of granzyme B confers lethality to a common viral infection

scientific article (publication date: December 2014)

A36-dependent actin filament nucleation promotes release of vaccinia virus

scientific article (publication date: March 2013)

Acute effects of parainfluenza virus on epithelial electrolyte transport.

scientific article published on 10 September 2004

Analysis of the Th1/Th2 paradigm in transplantation: interferon-gamma deficiency converts Th1-type proislet allograft rejection to a Th2-type xenograft-like response

scientific article published on 01 July 1999

Antiviral protection following immunization correlates with humoral but not cell-mediated immunity.

scientific article

Cytokines and immunity to viral infections

scientific article published on October 1, 1997

Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection

scientific article (publication date: 2015)

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

scientific article published on 18 September 2019

Draft Genome Sequence of an Isolate of Nontypeable Haemophilus influenzae from an Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Tasmania

scientific article published on 07 May 2020

Effects of vaccinia virus-expressed interleukin 2 on the immune system of sublethally irradiated mice

scientific article published on May 1, 1991

Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice

scientific article

Expression of cytokines by recombinant vaccinia viruses: a model for studying cytokines in virus infections in vivo

scientific article published on June 1, 1992

Genetic resistance to smallpox: lessons from mousepox.

scientific article published on January 2007

Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria

scientific article published on 27 April 2011

IL-12p40 and IL-18 play pivotal roles in orchestrating the cell-mediated immune response to a poxvirus infection.

scientific article published on 5 August 2009

Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

scientific article published on 28 December 2004

Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase

scientific article published on September 10, 1993

Interferon function is not required for recovery from a secondary poxvirus infection.

scientific article

LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins

scientific article published on 03 June 2018

Loss of Actin-Based Motility Impairs Ectromelia Virus Release In Vitro but Is Not Critical to Spread In Vivo

scientific article published on 5 March 2018

Loss of cytoskeletal transport during egress critically attenuates ectromelia virus infection in vivo

scientific article

Poxvirus CD8+ T-cell determinants and cross-reactivity in BALB/c mice

scientific article

Poxvirus-encoded TNF receptor homolog dampens inflammation and protects from uncontrolled lung pathology during respiratory infection

scientific article published on 12 October 2020

Propagation and Purification of Ectromelia Virus

scientific article published on 03 October 2018

Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice

scientific article

TNF deficiency dysregulates inflammatory cytokine production, leading to lung pathology and death during respiratory poxvirus infection

scientific article published on 22 June 2020

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

scientific journal article

Type 1 and type 2 cytokines in antiviral defense.

scientific article published in May 1998

Vaccine-induced protection against orthopoxvirus infection is mediated through the combined functions of CD4 T cell-dependent antibody and CD8 T cell responses

scientific article

Viral Replicative Capacity, Antigen Availability via Hematogenous Spread, and High TFH:TFR Ratios Drive Induction of Potent Neutralizing Antibody Responses

scientific article published on 05 March 2019