List of works - Bruno Alies

A new water-soluble Cu(II) chelator that retrieves Cu from Cu(amyloid-β) species, stops associated ROS production and prevents Cu(II)-induced Aβ aggregation.

scientific article published on 7 June 2012

A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity.

scientific article published on 5 May 2015

Chemical and functional properties of metal chelators that mobilize copper to elicit fungal killing of Cryptococcus neoformans

scientific article published on 17 November 2016

Concept for simultaneous and specific in situ monitoring of amyloid oligomers and fibrils via Förster resonance energy transfer

scientific article

Copper coordination to native N-terminally modified versus full-length amyloid-β: second-sphere effects determine the species present at physiological pH

scientific article published on 14 November 2012

Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance.

scientific article published in September 2018

Cu(II) binding to various forms of amyloid-β peptides. Are they friends or foes?

scientific article published on 01 January 2018

Cytidine- and guanosine-based nucleotide-lipids

scientific article published on 01 July 2018

Dynamics of Zn(II) binding as a key feature in the formation of amyloid fibrils by Aβ11-28

scientific article published on 13 December 2011

Free Superoxide is an Intermediate in the Production of H2O2 by Copper(I)-Aβ Peptide and O2.

scientific article published on 2 December 2015

Insights into the mechanisms of amyloid formation of Zn(II)-Ab11-28: pH-dependent zinc coordination and overall charge as key parameters for kinetics and the structure of Zn(II)-Ab11-28 aggregates

scientific article published on 05 July 2012

Methods and techniques to study the bioinorganic chemistry of metal–peptide complexes linked to neurodegenerative diseases

Mutations of Histidine 13 to Arginine and Arginine 5 to Glycine Are Responsible for Different Coordination Sites of Zinc(II) to Human and Murine Peptides

scientific article published on 27 August 2018

Nucleoside-Lipid-Based Nanocarriers for Sorafenib Delivery.

scientific article

Sequence proximity between Cu(II) and Cu(I) binding sites of human copper transporter 1 model peptides defines reactivity with ascorbate and O2.

scientific article published on 30 December 2015

Silver Ions Detection via Nucleolipids Self-Assembly

scientific article published on 10 January 2019

The role of metal ions in amyloid formation: general principles from model peptides.

scientific article published on March 2013

Zinc(II) Binding Site to the Amyloid-β Peptide: Insights from Spectroscopic Studies with a Wide Series of Modified Peptides.

scientific article published on 26 September 2016

Zinc(II) modulates specifically amyloid formation and structure in model peptides

scientific article published on 01 February 2011

Zn impacts Cu coordination to amyloid-β, the Alzheimer's peptide, but not the ROS production and the associated cell toxicity.

scientific article

pH-Dependent Cu(II) coordination to amyloid-β peptide: impact of sequence alterations, including the H6R and D7N familial mutations.

scientific article published on 6 October 2011

List of works by Bruno Alies

A new water-soluble Cu(II) chelator that retrieves Cu from Cu(amyloid-β) species, stops associated ROS production and prevents Cu(II)-induced Aβ aggregation.

A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity.

Chemical and functional properties of metal chelators that mobilize copper to elicit fungal killing of Cryptococcus neoformans

Concept for simultaneous and specific in situ monitoring of amyloid oligomers and fibrils via Förster resonance energy transfer

Copper coordination to native N-terminally modified versus full-length amyloid-β: second-sphere effects determine the species present at physiological pH

Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance.

Cu(II) binding to various forms of amyloid-β peptides. Are they friends or foes?

Cytidine- and guanosine-based nucleotide-lipids

Dynamics of Zn(II) binding as a key feature in the formation of amyloid fibrils by Aβ11-28

Free Superoxide is an Intermediate in the Production of H2O2 by Copper(I)-Aβ Peptide and O2.

Insights into the mechanisms of amyloid formation of Zn(II)-Ab11-28: pH-dependent zinc coordination and overall charge as key parameters for kinetics and the structure of Zn(II)-Ab11-28 aggregates

Methods and techniques to study the bioinorganic chemistry of metal–peptide complexes linked to neurodegenerative diseases

Mutations of Histidine 13 to Arginine and Arginine 5 to Glycine Are Responsible for Different Coordination Sites of Zinc(II) to Human and Murine Peptides

Nucleoside-Lipid-Based Nanocarriers for Sorafenib Delivery.

Sequence proximity between Cu(II) and Cu(I) binding sites of human copper transporter 1 model peptides defines reactivity with ascorbate and O2.

Silver Ions Detection via Nucleolipids Self-Assembly

The role of metal ions in amyloid formation: general principles from model peptides.

Zinc(II) Binding Site to the Amyloid-β Peptide: Insights from Spectroscopic Studies with a Wide Series of Modified Peptides.

Zinc(II) modulates specifically amyloid formation and structure in model peptides

Zn impacts Cu coordination to amyloid-β, the Alzheimer's peptide, but not the ROS production and the associated cell toxicity.

pH-Dependent Cu(II) coordination to amyloid-β peptide: impact of sequence alterations, including the H6R and D7N familial mutations.