List of works - Roberto Nitsch

A dual role for autophagy in a murine model of lung cancer

scientific article published in Nature Communications

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.

scientific article

Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene

scientific article

Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

scientific article published on 29 September 2020

HACE1 deficiency leads to structural and functional neurodevelopmental defects

scientific article published on 29 April 2019

HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases

scientific article published on 04 May 2020

HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.

scientific article published on 10 February 2014

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

scientific article published on January 2013

In vivo CRISPR editing with no detectable genome-wide off-target mutations

scientific article published in Nature

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer.

scientific article published on 8 November 2017

TNF-driven cell fate: till HACE do us part

scientific article published on 19 June 2016

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.

scientific article

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

scientific article published on 04 May 2016

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

scientific article published on September 2016

Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype

scientific article published on 19 February 2018

WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8 ⬇️

scientific article published on February 1, 2004

List of works by Roberto Nitsch

A dual role for autophagy in a murine model of lung cancer

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.

Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene

Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

HACE1 deficiency leads to structural and functional neurodevelopmental defects

HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases

HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

In vivo CRISPR editing with no detectable genome-wide off-target mutations

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer.

TNF-driven cell fate: till HACE do us part

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype

WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8 ⬇️