List of works - Carmine Settembre

A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts

scientific article published on 18 April 2013

A block of autophagy in lysosomal storage disorders

scientific article

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

scientific article

A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex

scientific article published on 17 December 2018

Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder

scientific article

Autophagy gets to the bone

scientific article

Autophagy in astrocytes: a novel culprit in lysosomal storage disorders

scientific article published on 9 October 2012

Beating the ER: novel insights into FAM134B function and regulation

scientific article published on 19 February 2020

Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders

scientific article published on 28 December 2020

Boning up on autophagy: the role of autophagy in skeletal biology

scientific article (publication date: 2014)

Cell metabolism: Autophagy transcribed

scientific article published in Nature

Cystic fibrosis: A disorder with defective autophagy

scientific article published on 01 January 2011

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

scientific article published on 15 August 2010

Direct conversion of fibroblasts into functional astrocytes by defined transcription factors

scientific article

Erratum: TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

scholarly article published in Nature Cell Biology

FGF signalling regulates bone growth through autophagy

scientific article published on 23 November 2015

Genetic control of bone formation

scientific article published on January 2009

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae

scientific article

Insulin granules. Insulin secretory granules control autophagy in pancreatic β cells

scientific article

Lysosomal adaptation: how the lysosome responds to external cues

scientific article

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.

scientific article published on March 2015

Lysosome: regulator of lipid degradation pathways

scientific article

Mechanisms by which autophagy regulates memory capacity in ageing

scientific article published on 30 July 2020

MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B

scientific article published on 27 July 2020

Molecular and functional analysis of SUMF1 mutations in multiple sulfatase deficiency

scientific article

New targets for old diseases: lessons from mucolipidosis type II.

scientific article

Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification

scientific article published on October 2008

Regulation of autophagosome biogenesis by OFD1-mediated selective autophagy

scientific article published on 28 December 2020

Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control

scientific article published on 02 August 2021

SUMF1 enhances sulfatase activities in vivo in five sulfatase deficiencies

scientific article

Self-eating in skeletal development: implications for lysosomal storage disorders

scientific article

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

scientific article

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum

scientific article

Sulfatases are determinants of alveolar formation

scientific article published on 18 February 2012

Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency

scholarly article

T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts

scientific article published on 17 January 2012

TFEB and the CLEAR network

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

scientific article published on 21 April 2013

TFEB controls vascular development by regulating the proliferation of endothelial cells

article

TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes ⬇️

scientific article published on November 1, 2011

Taurine deficiency as a driver of aging

scientific article published on 08 June 2023

Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.

scientific article published on 5 June 2014

List of works by Carmine Settembre

A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts

A block of autophagy in lysosomal storage disorders

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex

Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder

Autophagy gets to the bone

Autophagy in astrocytes: a novel culprit in lysosomal storage disorders

Beating the ER: novel insights into FAM134B function and regulation

Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders

Boning up on autophagy: the role of autophagy in skeletal biology

Cell metabolism: Autophagy transcribed

Cystic fibrosis: A disorder with defective autophagy

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

Direct conversion of fibroblasts into functional astrocytes by defined transcription factors

Erratum: TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

FGF signalling regulates bone growth through autophagy

Genetic control of bone formation

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae

Insulin granules. Insulin secretory granules control autophagy in pancreatic β cells

Lysosomal adaptation: how the lysosome responds to external cues

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.

Lysosome: regulator of lipid degradation pathways

Mechanisms by which autophagy regulates memory capacity in ageing

MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B

Molecular and functional analysis of SUMF1 mutations in multiple sulfatase deficiency

New targets for old diseases: lessons from mucolipidosis type II.

Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification

Regulation of autophagosome biogenesis by OFD1-mediated selective autophagy

Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control

SUMF1 enhances sulfatase activities in vivo in five sulfatase deficiencies

Self-eating in skeletal development: implications for lysosomal storage disorders

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum

Sulfatases are determinants of alveolar formation

Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency

T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts

TFEB and the CLEAR network

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

TFEB controls vascular development by regulating the proliferation of endothelial cells

TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes ⬇️

Taurine deficiency as a driver of aging

Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.