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List of works by John W Newman

12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms

scientific article published on 21 January 2011

A Randomized Placebo Controlled Trial of Ibuprofen for Respiratory Syncytial Virus Infection in a Bovine Model

scientific article

A diet containing a nonfat dry milk matrix significantly alters systemic oxylipins and the endocannabinoid 2-arachidonoylglycerol (2-AG) in diet-induced obese mice

scientific article

A method for the determination of environmental contaminants in living marine mammals using microscale samples of blubber and blood.

scientific article

A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes

scientific article published on 01 August 2018

A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction.

scientific article published on 31 January 2018

ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation

scientific article

Aberrant fatty acid metabolism in skeletal muscle contributes to insulin resistance in zinc transporter 7 (Znt7)-knockout mice.

scientific article

Abnormal lipoprotein oxylipins in metabolic syndrome and partial correction by omega-3 fatty acids.

scientific article published on 11 November 2017

Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons

scientific article published on 12 October 2016

Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.

scientific article published on January 2009

Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.

scientific article published in August 2004

An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats

scientific article

An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension

scientific article

Antioxidant supplementation and obesity have independent effects on hepatic oxylipin profiles in insulin-resistant, obesity-prone rats.

scientific article published on 20 September 2015

Arachidonate 5-lipoxygenase gene variants affect response to fish oil supplementation by healthy African Americans

scientific article

Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study.

scientific article published on April 2016

Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults.

scientific article published on 26 August 2013

Associations Among Fatty Acids, Desaturase and Elongase, and Insulin Resistance in Children

scientific article published on 18 October 2017

Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition.

scientific article published on 12 October 2005

Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers

scientific article published on 24 May 2012

Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets.

scientific article

Clinical and pathological characterization of northern elephant seal skin disease ⬇️

scientific article published on July 1, 1997

Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice

scientific article published on June 2007

Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum

scientific article published on 28 October 2019

Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice

journal article published in 2007

Congener-based Aroclor quantification and speciation techniques: a comparison of the strengths, weaknesses, and proper use of two alternative approaches.

scientific article

Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol

scientific article

Cytochrome p450-dependent lipid metabolism in preovulatory follicles.

scientific article

Daily consumption of orange-fleshed sweet potato for 60 days increased plasma β-carotene concentration but did not increase total body vitamin A pool size in Bangladeshi women

scientific article

Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters

scientific article

Diet-induced obesity and weight loss alter bile acid concentrations and bile acid-sensitive gene expression in insulin target tissues of C57BL/6J mice

scientific article

Dietary DHA reduces downstream endocannabinoid and inflammatory gene expression and epididymal fat mass while improving aspects of glucose use in muscle in C57BL/6J mice.

scientific article published on 29 July 2015

Dietary Docosahexaenoic Acid and trans-10, cis-12-Conjugated Linoleic Acid Differentially Alter Oxylipin Profiles in Mouse Periuterine Adipose Tissue

scientific article published on 13 April 2017

Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice.

scientific article

Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice

scientific article published on 4 October 2012

Direct comparison of fatty acid ratios in single cellular lipid droplets as determined by comparative Raman spectroscopy and gas chromatography.

scientific article

Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation

scientific article published on 21 August 2017

Effect of nutritional state on Hsp60 levels in the rotifer Brachionus plicatilis following toxicant exposure

scientific article published on 01 November 2002

Effect of omega-3 fatty acid ethyl esters on the oxylipin composition of lipoproteins in hypertriglyceridemic, statin-treated subjects

scientific article

Effect of trans fatty acid intake on abdominal and liver fat deposition and blood lipids: a randomized trial in overweight postmenopausal women

scientific article published on 31 January 2011

Effects of Dynamic Exercise on Plasma Arachidonic Acid Epoxides and Diols in Human Volunteers ⬇️

scientific article published on December 1, 2011

Effects of atopic dermatitis and gender on sebum lipid mediator and fatty acid profiles

scientific article published on 17 May 2018

Effects of pyridine exposure upon structural lipid metabolism in Swiss Webster mice.

scientific article published on 6 February 2008

Effects of short-term walnut consumption on human microvascular function and its relationship to plasma epoxide content.

scientific article

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway

scientific article

Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism.

scientific article published on 21 January 2004

Epoxide hydrolases: their roles and interactions with lipid metabolism

scientific article (publication date: 2005)

Establishing and Performing Targeted Multi-residue Analysis for Lipid Mediators and Fatty Acids in Small Clinical Plasma Samples

scientific article published in January 2018

Evaluation of fish models of soluble epoxide hydrolase inhibition

scientific article

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia

scientific article

Genetic contribution of the leukotriene pathway to coronary artery disease

scientific article

Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study

journal article published in 2006

Graded effects of proteinuria on HDL structure in nephrotic rats

scientific article

Habitual diets rich in dark-green vegetables are associated with an increased response to ω-3 fatty acid supplementation in Americans of African ancestry

scientific article

Habitual physical activity and plasma metabolomic patterns distinguish individuals with low vs. high weight loss during controlled energy restriction

scientific article

High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy

scientific article

IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal

scientific article published on 08 August 2012

Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates

scientific article published in 2024

Impact of circulating esterified eicosanoids and other oxylipins on endothelial function.

scientific article

Impact of post-collection freezing delay on the reliability of serum metabolomics in samples reflecting the California mid-term pregnancy biobank

scientific article published on 15 November 2018

Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin

scientific article (publication date: 2014)

In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea.

scientific article

Increased blood pressure in mice lacking cytochrome P450 2J5

scientific journal article

Increased expression of receptors for orexigenic factors in nodose ganglion of diet-induced obese rats

scientific article published on 03 February 2009

Individual metabolism should guide agriculture toward foods for improved health and nutrition.

scientific article

Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice

scientific article

Insulin induces a shift in lipid and primary carbon metabolites in a model of fasting-induced insulin resistance

scientific article

Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells.

scientific article published in December 2003

Lipid profiling following intake of the omega 3 fatty acid DHA identifies the peroxidized metabolites F4-neuroprostanes as the best predictors of atherosclerosis prevention

scientific article (publication date: 2014)

Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase

scientific article

Lipoprotein lipase releases esterified oxylipins from very low-density lipoproteins

scientific article

Mechanism of Mammalian Soluble Epoxide Hydrolase Inhibition by Chalcone Oxide Derivatives ⬇️

scientific article published on August 15, 1998

Methylmalonic acid quantification in low serum volumes by UPLC-MS/MS

scientific article published on 26 March 2011

Mutations in Durum Wheat SBEII Genes affect Grain Yield Components, Quality, and Fermentation Responses in Rats

scientific article published on 19 October 2015

Noninvasive profiling of sweat-derived lipid mediators for cutaneous research

scientific article published on 21 July 2018

Obesity-induced changes in lipid mediators persist after weight loss.

scientific article published in November 2017

Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial

scientific article published on 03 July 2017

Oral ibuprofen differentially affects plasma and sweat lipid mediator profiles in healthy adult males

scientific article published on 17 May 2018

Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model ⬇️

scientific article published on December 12, 2012

Oxylipins in triglyceride-rich lipoproteins of dyslipidemic subjects promote endothelial inflammation following a high fat meal

scientific article published on 17 June 2019

Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression.

scientific article

Peptidyl-urea based inhibitors of soluble epoxide hydrolases.

scientific article published on October 2006

Perinatal exposure of mice to the pesticide DDT impairs energy expenditure and metabolism in adult female offspring

scientific article

Perinatal triphenyl phosphate exposure accelerates type 2 diabetes onset and increases adipose accumulation in UCD-type 2 diabetes mellitus rats.

scientific article published on 12 July 2016

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

scientific article

Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women.

scientific article published on 15 April 2009

Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study

scientific article published on 24 May 2016

Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women

scientific article

Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets

scientific article published on 29 March 2013

Prebiotic milk oligosaccharides prevent development of obese phenotype, impairment of gut permeability, and microbial dysbiosis in high fat-fed mice

scientific article

Proteinuria increases oxylipid concentrations in VLDL and HDL but not LDL particles in the rat

scientific article published on 11 May 2007

Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery

scientific article published on 20 July 2012

Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model ⬇️

scientific article published on December 22, 2011

Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function

scientific article

Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways.

scientific article

Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.

scientific article published in May 2004

Soluble epoxide hydrolase is a therapeutic target for acute inflammation

scientific article

Structural equation modeling of food craving across the menstrual cycle using behavioral, neuroendocrine, and metabolic factors

scientific article published on 18 July 2018

Sweat lipid mediator profiling: a noninvasive approach for cutaneous research.

scientific article published on 8 November 2016

The Effect of Docosahexaenoic Acid ont10,c12-Conjugated Linoleic Acid-Induced Changes in Fatty Acid Composition of Mouse Liver, Adipose, and Muscle ⬇️

scientific article published on November 21, 2012

The Postprandial Effects of a Moderately High-Fat Meal on Lipid Profiles and Vascular Inflammation in Alzheimer's Disease Patients: A Pilot Study.

scientific article published on January 2014

The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects

scientific article published on 15 December 2015

The human serum metabolome ⬇️

scientific article

The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells

scientific article

The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity

scientific article

Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase

scientific article (publication date: April 2000)

Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation

scientific article

Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids

scientific article

Umbilical cord blood metabolomics reveal distinct signatures of dyslipidemia prior to bronchopulmonary dysplasia and pulmonary hypertension

scientific article published on 16 August 2018

Variation in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful? ⬇️

scientific article published on March 29, 2012

Vitamin B-12 supplementation of rural Mexican women changes biochemical vitamin B-12 status indicators but does not affect hematology or a bone turnover marker

scientific article published on 22 August 2012

Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research

scientific article

Zinc transporter 7 deficiency affects lipid synthesis in adipocytes by inhibiting insulin-dependent Akt activation and glucose uptake

scientific article published on 2 November 2015

imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel ⬇️

scientific article published on July 18, 2012

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