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List of works by Rob J Vreeken

A branched biosynthetic pathway is involved in production of roquefortine and related compounds in Penicillium chrysogenum.

scientific article

A lipidomic analysis approach to evaluate the response to cholesterol-lowering food intake

scientific article

A mutasynthesis approach with a Penicillium chrysogenum ΔroqA strain yields new roquefortine D analogues

scientific article published on 12 March 2015

A non-canonical NRPS is involved in the synthesis of fungisporin and related hydrophobic cyclic tetrapeptides in Penicillium chrysogenum

scientific article (publication date: 2014)

A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice

scientific article

Altered expression of epidermal lipid bio-synthesis enzymes in atopic dermatitis skin is accompanied by changes in stratum corneum lipid composition

article

Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters

scientific article

Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry

scientific article

Attenuation of Slc27a5 Gene Expression Followed by LC–MS Measurement of Bile Acid Reconjugation Using Metabolomics and a Stable Isotope Tracer Strategy ⬇️

scientific article published on August 26, 2011

Automated pipeline for de novo metabolite identification using mass-spectrometry-based metabolomics

scientific article published on 21 March 2013

Capillary electrochromatography/nanoelectrospray mass spectrometry for attomole characterization of peptides

scientific article published on 01 January 2000

Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma

scientific article

Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes.

scientific article

Comprehensive LC-MS E lipidomic analysis using a shotgun approach and its application to biomarker detection and identification in osteoarthritis patients

scientific article published in May 2010

Comprehensive metabolomics to evaluate the impact of industrial processing on the phytochemical composition of vegetable purees

article

Cross-Species Molecular Imaging of Bile Salts and Lipids in Liver: Identification of Molecular Structural Markers in Health and Disease

article

Deregulation of secondary metabolism in a histone deacetylase mutant of Penicillium chrysogenum.

scientific article published on 24 March 2018

Determination of daminozide in apples and apple leaves by liquid chromatography--mass spectrometry

scientific article

Determination of oxytetracycline and its degradation products by high-performance liquid chromatography-tandem mass spectrometry in manure-containing anaerobic test systems

scientific article

Determination of polar organophosphorus pesticides in aqueous samples by direct injection using liquid chromatography-tandem mass spectrometry

scientific article

Development and application of a UHPLC-MS/MS metabolomics based comprehensive systemic and tissue-specific screening method for inflammatory, oxidative and nitrosative stress.

scientific article

Direct nose to brain delivery of small molecules: critical analysis of data from a standardized in vivo screening model in rats

scientific article published on 01 December 2020

Endometriosis is associated with aberrant metabolite profiles in plasma

scientific article

Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection

scientific article published on 2 June 2014

Enhanced performance for the analysis of prostaglandins and thromboxanes by liquid chromatography-tandem mass spectrometry using a new atmospheric pressure ionization source.

scientific article

Evaluation of eluents in thermospray liquid chromatography-mass spectrometry for identification and determination of pesticides in environmental samples

scientific article published on 01 August 1991

Fetal Metabolic Stress Disrupts Immune Homeostasis and Induces Proinflammatory Responses in Human Immunodeficiency Virus Type 1- and Combination Antiretroviral Therapy-Exposed Infants

scientific article published on 17 June 2017

First-Trimester Serum Acylcarnitine Levels to Predict Preeclampsia: A Metabolomics Approach

scientific article published on 4 June 2015

Fragmentation trees for the structural characterisation of metabolites ⬇️

scientific article published in October 2012

Gas Pressure Assisted Microliquid–Liquid Extraction Coupled Online to Direct Infusion Mass Spectrometry: A New Automated Screening Platform for Bioanalysis

scientific article published on 02 October 2014

Gender-Dependent Associations of Metabolite Profiles and Body Fat Distribution in a Healthy Population with Central Obesity: Towards Metabolomics Diagnostics

article

Generic solid phase extraction–liquid chromatography–tandem mass spectrometry method for fast determination of drugs in biological fluids

article

Genomic mutational analysis of the impact of the classical strain improvement program on β-lactam producing Penicillium chrysogenum

scientific article published on 14 November 2015

High sensitivity and selectivity in quantitative analysis of drugs in biological samples using 4-column multidimensional micro-UHPLC-MS enabling enhanced sample loading capacity

scientific article

Identification of a Polyketide Synthase Involved in Sorbicillin Biosynthesis by Penicillium chrysogenum. ⬇️

scientific article published on 22 April 2016

Identifying Static and Kinetic Lipid Phenotypes by High Resolution UPLC–MS: Unraveling Diet-Induced Changes in Lipid Homeostasis by Coupling Metabolomics and Fluxomics ⬇️

article by Jose M. Castro-Perez et al published 2 September 2011 in Journal of Proteome Research

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS ⬇️

scientific article published on September 30, 2010

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients

scientific article

Increased Presence of Monounsaturated Fatty Acids in the Stratum Corneum of Human Skin Equivalents

scientific article published on 16 August 2012

Integrating metabolomics profiling measurements across multiple biobanks.

scientific article published on 16 April 2014

Integration of Ion Mobility MSE after Fully Automated, Online, High-Resolution Liquid Extraction Surface Analysis Micro-Liquid Chromatography

scientific article published on 25 September 2017

Intercellular skin barrier lipid composition and organization in Netherton syndrome patients.

scientific article

Ionisation efficiencies can be predicted in complicated biological matrices: A proof of concept

scientific article published on 31 May 2018

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery

scientific article

Lamellar Lipid Organization and Ceramide Composition in the Stratum Corneum of Patients with Atopic Eczema

article

Lipidomics of familial longevity

scientific article published on 02 April 2013

Liquid chromatography with triple-quadrupole and quadrupole-time-of-flight mass spectrometry for the determination of micro-constituents - a comparison

scientific article published on 5 February 2004

Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry

scientific article

Mass spectrometric analysis of intact human monoclonal antibody aggregates fractionated by size-exclusion chromatography.

scientific article

Mass spectrometric recommendations for Quan/Qual analysis using liquid-chromatography coupled to quadrupole time-of-flight mass spectrometry

scientific article published on 03 March 2018

Matrix Effect Compensation in Small-Molecule Profiling for an LC-TOF Platform Using Multicomponent Postcolumn Infusion.

scientific article published on 27 May 2015

Metabolic characterization of the natural progression of chronic hepatitis B.

scientific article published on 10 June 2016

Metabolic phenotyping reveals a lipid mediator response to ionizing radiation

scientific article

Metabolite Identification Using Automated Comparison of High-Resolution Multistage Mass Spectral Trees

scientific article

Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis

scientific article published on 16 April 2011

Metabolomics profiling for identification of novel potential markers in early prediction of preeclampsia.

scientific article

Metabolomics profiling of the free and total oxidised lipids in urine by LC-MS/MS: application in patients with rheumatoid arthritis

scientific article published on 12 July 2016

Modulation of stratum corneum lipid composition and organization of human skin equivalents by specific medium supplements.

scientific article published on 14 July 2015

Novel key metabolites reveal further branching of the roquefortine/meleagrin biosynthetic pathway.

scientific article published on 13 November 2013

On-line post-column Diels-Alder derivatization for the determination of vitamin D3 and its metabolites by liquid chromatography/thermospray mass spectrometry

scientific article published on 01 November 1993

Oxylipin profiling in endothelial cells in vitro - Effects of DHA and hydrocortisone upon an inflammatory challenge

scientific article published on 28 June 2019

Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability

scientific article

Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets

scientific article published on 29 March 2013

Postprandial fatty acid specific changes in circulating oxylipins in lean and obese men after high-fat challenge tests.

scientific article published on 14 October 2013

Potent peptidic fusion inhibitors of influenza virus

scientific article published on 28 September 2017

Quantitative analysis of ceramides using a novel lipidomics approach with three dimensional response modelling.

scientific article published on 12 July 2016

Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery

scientific article published on 20 July 2012

Rapid target analysis of microcontaminants in water by on-line single-short-column liquid chromatography combined with atmospheric pressure chemical ionization tandem mass spectrometry.

scientific article

Roux-en-Y gastric bypass surgery, but not calorie restriction, reduces plasma branched-chain amino acids in obese women independent of weight loss or the presence of type 2 diabetes

scientific article published on 14 October 2014

Serum-Based Oxylipins Are Associated with Outcomes in Primary Prevention Implantable Cardioverter Defibrillator Patients

scientific article

Skin barrier dysfunction in non-lesional atopic eczema: the role of stratum corneum lipids

scientific article published on 09 April 2013

Systematic evaluation of commercially available ultra-high performance liquid chromatography columns for drug metabolite profiling: optimization of chromatographic peak capacity

scientific article published on 20 November 2014

Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization combined with Triple Quadrupole Mass Spectrometry

article

Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen

scientific article

The Impact of Delayed Storage on the Measured Proteome and Metabolome of Human Cerebrospinal Fluid

scientific article published on 13 October 2011

The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF).

scientific article

The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients

scientific article published on 01 January 2014

The pharmacokinetics and pharmacological effect of (S)-5-OH-DPAT following controlled delivery with transdermal iontophoresis

scientific article

Three-phase electroextraction: a new (online) sample purification and enrichment method for bioanalysis

scientific article published on 13 June 2013

Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice.

scientific article

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