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List of works by Chuanju Liu

A Semi-Quantitative Drug Affinity Responsive Target Stability (DARTS) assay for studying Rapamycin/mTOR interaction

scientific article published on 27 August 2019

A disintegrin and metalloprotease with thrombospondin type I motif 7: a new protease for connective tissue growth factor in hepatic progenitor/oval cell niche.

scientific article published on 2 April 2015

A novel mechanism of EAE resistance highlights the conflicting roles of progranulin-mediated immunosuppression and antigen processing

scientific article published on 11 September 2019

A solid-phase assay for studying direct binding of progranulin to TNFR and progranulin antagonism of TNF/TNFR interactions

scientific article published on January 2014

ADAMTS-12: a multifaced metalloproteinase in arthritis and inflammation

scientific article

ADAMTS-18: a metalloproteinase with multiple functions

scientific article published on June 2014

ADAMTS-7 mediates vascular smooth muscle cell migration and neointima formation in balloon-injured rat arteries

scientific article

ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor

scientific article published on June 2009

ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant

scientific article published on 14 February 2013

ATF6a, a Runx2-activable transcription factor, is a new regulator of chondrocyte hypertrophy

scientific article published on 2 November 2015

Acute renal insufficiency, supraventricular tachycardia, and confusion after recombinant human bone morphogenetic protein-2 implantation for lumbosacral spine fusion

scientific article published on June 2008

Administration of human recombinant bone morphogenetic protein-2 for spine fusion may be associated with transient postoperative renal insufficiency.

scientific article published on April 2010

Association of the 16-kDa subunit c of vacuolar proton pump with the ileal Na+-dependent bile acid transporter: protein-protein interaction and intracellular trafficking.

scientific article published on 29 January 2004

Brain-penetrant heat shock protein amplifier arimoclomol enhances GCase activity in in vitro Gaucher disease models

scientific article published on 03 December 2018

Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties.

scientific article

Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation

scientific journal article

Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.

scientific article published on 24 February 2011

Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin

scientific journal article

Cbfa1-dependent expression of an interferon-inducible p204 protein is required for chondrocyte differentiation

scientific article published on 18 July 2008

Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease.

scientific article published on 30 January 2018

Chondro-protective effects of low intensity pulsed ultrasound.

scientific article published on 27 June 2016

Clinical Application of Teriparatide in Fracture Prevention: A Systematic Review

scientific article published on 01 January 2019

Direct interaction with contactin targets voltage-gated sodium channel Na(v)1.9/NaN to the cell membrane.

scientific article

Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?: Comment on Olson et al.: "Therapeutic Opportunities to Prevent Post-Traumatic Arthritis: Lessons From the Natural History of Arthritis Afte

scientific article published on 31 October 2015

Effects of the myeloid cell nuclear differentiation antigen on the proliferation, apoptosis and migration of osteosarcoma cells

scientific article published on 17 January 2014

Establishment of a Modified Collagen-Induced Arthritis Mouse Model to Investigate the Anti-inflammatory Activity of Progranulin in Inflammatory Arthritis

scientific article published on 01 January 2018

Establishment of a surgically-induced model in mice to investigate the protective role of progranulin in osteoarthritis

scientific article

Expression of bone morphogenetic proteins by Dupuytren's fibroblasts

scientific article published on 01 September 2004

Expression of bone morphogenetic proteins, receptors, and tissue inhibitors in human fetal, adult, and osteoarthritic articular cartilage

scientific article

Extracellular matrix protein 1, a direct targeting molecule of parathyroid hormone-related peptide, negatively regulates chondrogenesis and endochondral ossification via associating with progranulin growth factor.

scientific article published on 13 April 2016

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice

scientific article published on 29 October 2019

FGFR3 induces degradation of BMP type I receptor to regulate skeletal development

scientific article

Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis

scientific article published on 13 July 2019

Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice

scientific article published on 02 January 2020

Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis

scientific article published on 23 December 2016

GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation.

scientific article published on 17 December 2011

GEP, a local growth factor, is critical for odontogenesis and amelogenesis.

scientific article

Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis.

scientific article

IFI16 inhibits tumorigenicity and cell proliferation of bone and cartilage tumor cells.

scientific article

IRE1a constitutes a negative feedback loop with BMP2 and acts as a novel mediator in modulating osteogenic differentiation

scientific article

In Vitro Physical and Functional Interaction Assays to Examine the Binding of Progranulin Derivative Atsttrin to TNFR2 and Its Anti-TNFα Activity

scientific article published on 01 January 2021

Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin

scientific article

Insights into the role of progranulin in immunity, infection, and inflammation ⬇️

scientific article published on October 22, 2012

Interaction between cartilage oligomeric matrix protein and extracellular matrix protein 1 mediates endochondral bone growth.

scientific article

Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice

scientific article published on 24 January 2020

Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis

scientific article

Levels of expression for BMP-7 and several BMP antagonists may play an integral role in a fracture nonunion: a pilot study

scientific article

Lipoatrophy and metabolic disturbance in mice with adipose-specific deletion of kindlin-2

scientific article published on 11 July 2019

Matrix metalloproteinases that associate with and cleave bone morphogenetic protein-2 in vitro are elevated in hypertrophic fracture nonunion tissue.

scientific article

Mediation of chondrogenic and osteogenic differentiation by an interferon-inducible p202 protein.

scientific article published on November 2008

MicroRNAs in skeletogenesis

scientific article published on January 2009

Modified yeast-two-hybrid system to identify proteins interacting with the growth factor progranulin.

scientific article

Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B

scientific article

Molecular regulations and therapeutic targets of Gaucher disease.

scientific article published on 11 April 2018

Monitoring Atsttrin-Mediated Inhibition of TNFα/NF-κβ Activation Through In Vivo Bioluminescence Imaging

scientific article published on 01 January 2021

MyoD-dependent induction during myoblast differentiation of p204, a protein also inducible by interferon.

scientific article published on September 2000

Overexpression of ADAMTS-7 leads to accelerated initiation and progression of collagen-induced arthritis in mice

scientific article published on 6 March 2015

PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner

scientific article published on 12 November 2014

Prevention of atrophic nonunion by the systemic administration of parathyroid hormone (PTH 1-34) in an experimental animal model

scientific article published on 01 December 2012

Progranulin acts as a shared chaperone and regulates multiple lysosomal enzymes.

scientific article published on 23 June 2017

Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease

scientific article published on 20 October 2018

Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice

scientific article published on 27 November 2019

Progranulin deficiency exaggerates, whereas progranulin-derived Atsttrin attenuates, severity of dermatitis in mice.

scientific article

Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models.

scientific article published on 19 December 2017

Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.

scientific article

Progranulin inhibition of TNFα

scientific article published on 11 February 2014

Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner

scientific article published on 19 February 2016

Progranulin promotes diabetic fracture healing in mice with type 1 diabetes

scientific article published on 18 August 2019

Progranulin: A conductor of receptors orchestra, a chaperone of lysosomal enzymes and a therapeutic target for multiple diseases

scientific article published on 30 January 2019

Progranulin: A key player in autoimmune diseases.

scientific article published on 12 August 2016

Progranulin: a growth factor, a novel TNFR ligand and a drug target

scientific article published on 8 October 2011

Progranulin: a promising therapeutic target for rheumatoid arthritis.

scientific article

Prolyl hydroxylase domain proteins regulate bone mass through their expression in osteoblasts.

scientific article published on 7 September 2016

RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity.

scientific article published on 24 April 2018

RbAp48 is a critical mediator controlling the transforming activity of human papillomavirus type 16 in cervical cancer.

scientific article

Regulation of chondrocyte differentiation by ADAMTS-12 metalloproteinase depends on its enzymatic activity.

scientific article

Regulation of chondrocyte differentiation by IRE1α depends on its enzymatic activity

scientific article

Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction

scientific article published on 18 November 2020

Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16

scientific article published on 11 January 2012

Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling

scientific article

Role of ADAMTS-12 in Protecting Against Inflammatory Arthritis in Mice By Interacting With and Inactivating Proinflammatory Connective Tissue Growth Factor

scientific article published on 24 September 2018

Serum interleukin-6 as a marker of periprosthetic infection following total hip and knee arthroplasty

scientific article published on 01 September 2005

Serum progranulin levels in Hispanic rheumatoid arthritis patients treated with TNF antagonists: a prospective, observational study

scientific article published on 9 November 2016

Targeting tumor necrosis factor receptors in ankylosing spondylitis

scientific article published on 15 July 2018

The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice.

scientific article published on 21 November 2016

The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases.

scientific article published on 22 September 2009

The increase in levels of interferon-inducible proteins p202a and p202b and RNA-dependent protein kinase (PKR) during myoblast differentiation is due to transactivation by MyoD: their tissue distribution in uninfected mice does not depend on interfe

scientific article published on June 2002

The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation

scientific journal article

The p200 family protein p204 as a modulator of cell proliferation and differentiation: a brief survey

scientific article

The retinoblastoma protein is an essential mediator of osteogenesis that links the p204 protein to the Cbfa1 transcription factor thereby increasing its activity.

scientific article published on 17 April 2007

The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.

scientific article published on January 2009

The role of ADAMTSs in arthritis ⬇️

scientific article published on February 7, 2010

The role of PGRN in musculoskeletal development and disease

scientific article published on January 2014

The role of progranulin in arthritis.

scientific article

The roles of interferon-inducible p200 family members IFI16 and p204 in innate immune responses, cell differentiation and proliferation

scientific article published on March 2015

Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity.

scientific article published on June 2014

Transcriptional mechanism of COMP gene expression and chondrogenesis

scientific article

XBP1S Associates with RUNX2 and Regulates Chondrocyte Hypertrophy ⬇️

scientific article published on August 3, 2012

p204 protein overcomes the inhibition of core binding factor alpha-1-mediated osteogenic differentiation by Id helix-loop-helix proteins.

scientific article published on 20 February 2008

p204 protein overcomes the inhibition of the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes by Id proteins.

scientific article published on 22 March 2006

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