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List of works by Guglielmo Roma

A Simple and Efficient CRISPR Technique for Protein Tagging

scientific article published on 05 December 2020

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi.

scientific article published on 7 December 2017

A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples

scientific article

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells

scientific article published on 31 May 2007

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

scientific article published in Nature

AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells ⬇️

scientific article published on February 29, 2012

AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

scientific article published on 19 December 2019

Active poly(ADPribose) metabolism in DNAase- and salt-resistant rat testis chromatin with high transcriptional activity/competence

scientific journal article

Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues

scientific article published on 01 September 2019

Age-associated inflammation inhibits epidermal stem cell function

scientific article published on 12 September 2012

An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells

scientific article published on 24 August 2020

Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

scientific article published on 01 April 2020

CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations

scientific article

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.

scientific article published on 4 February 2016

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

scientific article published on 09 December 2019

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

scientific article published on 01 September 2020

CellSIUS provides sensitive and specific detection of rare cell populations from complex single cell RNA-seq data

scholarly article published 9 January 2019

CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

scientific article published on 17 July 2019

Comparative transcriptomics of early dipteran development

scientific article

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

scientific article published on 01 September 2015

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

scientific article published on 01 April 2016

Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size

scientific article published in October 2016

Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon

scientific article

Discovery of a ZIP7 inhibitor from a Notch pathway screen

scientific article published on 14 January 2019

E-box-independent regulation of transcription and differentiation by MYC.

scientific article published on 23 October 2011

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

scientific article

Farnesoid X Receptor Agonism, Acetyl-Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model

scientific article published on 08 November 2019

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

scientific article

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy

scientific article published on 21 December 2017

Genomic Analysis Revealed New Oncogenic Signatures in TP53-Mutant Hepatocellular Carcinoma.

scientific article published on 2 February 2018

Hi-Cpipe: a pipeline for high-throughput chromosome capture

HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.

scientific article published on 20 February 2017

HumMeth27QCReport: an R package for quality control and primary analysis of Illumina Infinium methylation data

scientific article

IRF2 is a master regulator of human keratinocyte stem cell fate

scientific article published on 14 October 2019

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.

scientific article

Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

scientific article

Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells ⬇️

scientific article published on August 12, 2013

Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis

scientific article published on 13 February 2020

Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances

scientific article published on 14 January 2016

Lack of sik1 in mouse embryonic stem cells impairs cardiomyogenesis by down-regulating the cyclin-dependent kinase inhibitor p57kip2

scientific journal article

Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells

scientific article published on 29 August 2019

MiR-210 promotes sensory hair cell formation in the organ of corti

scientific article

MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae

scientific article published on 6 November 2014

Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells

scientific article

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

scientific article published on 20 August 2019

PRGdb 2.0: towards a community-based database model for the analysis of R-genes in plants

scientific article (publication date: 2013)

PRGdb: a bioinformatics platform for plant resistance gene analysis

scientific article

PipeIT: A Singularity Container for Molecular Diagnostic Somatic Variant Calling on the Ion Torrent Next-Generation Sequencing Platform

scientific article published on 21 June 2019

Regulation of Human Epidermal Stem Cell Proliferation and Senescence Requires Polycomb- Dependent and -Independent Functions of Cbx4

Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4.

scientific article published in September 2011

Rosiglitazone and AS601245 Decrease Cell Adhesion and Migration through Modulation of Specific Gene Expression in Human Colon Cancer Cells ⬇️

scientific article published on June 28, 2012

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

scientific article

Screening of Intestinal Crypt Organoids: A Simple Readout for Complex Biology

scholarly article published 6 January 2017

Self-organization and symmetry breaking in intestinal organoid development

scientific article published on 24 April 2019

SuperFly: a comparative database for quantified spatio-temporal gene expression patterns in early dipteran embryos

scientific article published on 17 November 2014

TEQC: an R package for quality control in target capture experiments

scientific article published on 12 March 2011

TORC1 inhibition enhances immune function and reduces infections in the elderly

scientific article published on 01 July 2018

TRRAP is a central regulator of human multiciliated cell formation.

scientific article

The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

scientific article published on 28 August 2020

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

scientific article published on 18 April 2016

The UniTrap resource: tools for the biologist enabling optimized use of gene trap clones.

scientific article published on 16 October 2007

The exon quantification pipeline (EQP): a comprehensive approach to the quantification of gene, exon and junction expression from RNA-seq data

scientific article

The genome of melon (Cucumis melo L.).

scientific article

The liver-specific protein 2 (LISP2) is an early marker of liver stage development

scientific article published on 16 May 2019

Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite during progression into dormancy

scientific article published on 27 December 2018

UTS2B Defines a Novel Enteroendocrine Cell Population and Regulates GLP-1 Secretion Through SSTR5 in Male Mice

scientific article published on 01 December 2019

Widespread generation of alternative UTRs contributes to sex-specific RNA binding by UNR

scientific article published on 18 November 2011

X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome

scientific article published on 16 August 2018

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury

scientific article published on 09 May 2019

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

scientific article published on 21 August 2015

mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level

article published in the Proceedings of the National Academy of Sciences of the United States of America

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