List of works - Emma Scotter

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

scientific article published on 7 March 2013

ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function

scientific article published on 08 June 2020

Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells

scientific article

An anti-inflammatory role for C/EBPδ in human brain pericytes

scientific article published on 13 July 2015

Antisense oligonucleotide therapies for Amyotrophic Lateral Sclerosis: Existing and emerging targets

scientific article published on 20 March 2019

C9ORF72 and UBQLN2 mutations are causes of amyotrophic lateral sclerosis in New Zealand: a genetic and pathologic study using banked human brain tissue.

scientific article published on 5 July 2016

Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus

scientific article published on 26 February 2021

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?

scientific article published on 14 February 2005

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

scientific article

Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

scientific article published on 22 October 2014

Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic

scientific article

High throughput quantification of mutant huntingtin aggregates

scientific article

Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway.

scientific article published on 24 July 2006

Markers for human brain pericytes and smooth muscle cells

scientific article published on 07 June 2018

Motor neurone disease: bringing New Zealand patients onto the world stage

scientific article

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

scientific article

Neuromuscular disease: new insights and avenues for therapy.

scientific article published on January 2013

Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.

scientific article

Novel mutations support a role for Profilin 1 in the pathogenesis of ALS.

scientific article

Single-cell image analysis reveals a protective role for microglia in glioblastoma

scientific article published on 01 January 2021

Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!

scientific article

TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

scientific article

The endocannabinoid system as a target for the treatment of neurodegenerative disease

scientific article

The therapeutic potential of G-protein coupled receptors in Huntington's disease

scientific article published on 11 August 2010

Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.

scientific article

List of works by Emma Scotter

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function

Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells

An anti-inflammatory role for C/EBPδ in human brain pericytes

Antisense oligonucleotide therapies for Amyotrophic Lateral Sclerosis: Existing and emerging targets

C9ORF72 and UBQLN2 mutations are causes of amyotrophic lateral sclerosis in New Zealand: a genetic and pathologic study using banked human brain tissue.

Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic

High throughput quantification of mutant huntingtin aggregates

Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway.

Markers for human brain pericytes and smooth muscle cells

Motor neurone disease: bringing New Zealand patients onto the world stage

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

Neuromuscular disease: new insights and avenues for therapy.

Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.

Novel mutations support a role for Profilin 1 in the pathogenesis of ALS.

Single-cell image analysis reveals a protective role for microglia in glioblastoma

Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!

TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

The endocannabinoid system as a target for the treatment of neurodegenerative disease

The therapeutic potential of G-protein coupled receptors in Huntington's disease

Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.