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List of works by Christophe Caux

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

A Milestone Review on How Macrophages Affect Tumor Growth

scientific article published on November 2016

A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system

scientific article published on 12 April 2019

A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment

scientific article

A novel regulation of PD-1 ligands on mesenchymal stromal cells through MMP-mediated proteolytic cleavage.

scientific article

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

scientific article

Activation of human dendritic cells through CD40 cross-linking.

scientific article published on October 1994

Activation of primary allogeneic CD8+ T cells by dendritic cells generated in vitro from CD34+ cord blood progenitor cells

scientific article published on 01 January 1995

Antigen uptake by dendritic cells

scientific article published on 01 January 2001

Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints

scientific article published on 20 March 2018

Autocrine role for Gas6 with Tyro3 and Axl in leiomyosarcomas

scientific article published on 25 January 2013

BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells.

scientific article published on 13 October 2017

Breast Cancer Cell-Derived GM-CSF Licenses Regulatory Th2 Induction by Plasmacytoid Predendritic Cells in Aggressive Disease Subtypes

scientific article published on 14 May 2015

Breast cancer-derived transforming growth factor-β and tumor necrosis factor-α compromise interferon-α production by tumor-associated plasmacytoid dendritic cells.

scientific article published on 8 March 2013

Breast carcinoma cells promote the differentiation of CD34+ progenitors towards 2 different subpopulations of dendritic cells with CD1a(high)CD86(-)Langerin- and CD1a(+)CD86(+)Langerin+ phenotypes.

scientific article published on July 2004

CCL1-CCR8 Interactions: An Axis Mediating the Recruitment of T Cells and Langerhans-Type Dendritic Cells to Sites of Atopic Skin Inflammation

article by M. Gombert et al published 6 April 2005 in Journal of Immunology

CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells

scientific article

CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues

scientific article published on 21 September 2011

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha

scientific article published on 01 January 1997

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor alpha: II. Functional analysis

article

CD4 lymphopenia to identify end-of-life metastatic cancer patients

scientific article published on 13 December 2012

CD73 expression and clinical significance in human metastatic melanoma.

scientific article published in June 2018

CD73 expression in normal and pathological human hepatobiliopancreatic tissues

scientific article published on 04 January 2019

Cell proliferation and survival induced by Toll-like receptors is antagonized by type I IFNs

scholarly article

Characterization of human CD34+ derived dendritic/Langerhans cells (D-Lc)

scientific article published on 01 January 1995

Cold Tumors: A Therapeutic Challenge for Immunotherapy

scientific article published on 08 February 2019

Combined and sequential effects of human IL-3 and GM-CSF on the proliferation of CD34+ hematopoietic cells from cord blood.

scientific article

CpG promotes cross-presentation of dead cell-associated antigens by pre-CD8α+ dendritic cells [corrected].

scientific article published on 27 December 2010

Critical role of IL-12 in dendritic cell-induced differentiation of naive B lymphocytes

scientific article published on September 1, 1998

Critical role of ITIM-bearing FcgammaR on DCs in the capture and presentation of native antigen to B cells

scientific article published on 01 November 2005

Dendritic Cell Development: Multiple Pathways to Nature's Adjuvants

scientific article published on January 1, 1997

Dendritic cells directly modulate B cell growth and differentiation.

scientific article

Dendritic cells enhance the differentiation of naïve B cells into plasma cells in vitro

scientific article published on 01 December 1998

Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

scientific article published in February 2006

Description of the immune microenvironment of chondrosarcoma and contribution to progression.

scientific article published on 7 December 2016

Differences in tumor regulatory T-cell localization and activation status impact patient outcome.

scientific article published on 06 October 2009

Disequilibrium of BMP2 levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response

scientific article

Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses

scientific article published on 01 September 2005

Distribution of surface-membrane molecules on bone marrow and cord blood CD34+ hematopoietic cells

scientific article published on 01 January 1992

ELYPSE-7: a randomized placebo-controlled phase IIa trial with CYT107 exploring the restoration of CD4+ lymphocyte count in lymphopenic metastatic breast cancer patients.

scientific article published on 07 April 2015

ELYPSE-7: a randomized placebo-controlled phase IIa trial with CYT107 exploring the restoration of CD4+ lymphocyte count in lymphopenic metastatic breast cancer patients.

scientific article

Early detection of tumor cells by innate immune cells leads to T(reg) recruitment through CCL22 production by tumor cells

scientific article

Effects of recombinant human interleukin-3 on CD34-enriched normal hematopoietic progenitors and on myeloblastic leukemia cells

scientific article published on 01 November 1988

Emerging Role of the Unfolded Protein Response in Tumor Immunosurveillance.

scientific article

Expression of macrophage inflammatory protein-3alpha, stromal cell-derived factor-1, and B-cell-attracting chemokine-1 identifies the tonsil crypt as an attractive site for B cells

scientific article published on 01 June 2001

Fc receptor gamma-chain activation via hOSCAR induces survival and maturation of dendritic cells and modulates Toll-like receptor responses

scientific article

Follicular B Lymphomas Generate Regulatory T Cells via the ICOS/ICOSL Pathway and Are Susceptible to Treatment by Anti-ICOS/ICOSL Therapy.

scientific article

Functional CD40 antigen on B cells, dendritic cells and fibroblasts.

scientific article published on January 1995

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

scientific article published in Nature

Genetic alterations and tumor immune attack in Yo paraneoplastic cerebellar degeneration

scientific article published on 3 January 2018

Hot topics in 2017 in oncology and hematology. A selection by the editorial board of Bulletin du Cancer

scientific article published on 18 December 2017

Human Dendritic/Langerhans Cells Control Growth and Differentiation of CD40 Activated B Cells

scientific article published on January 1, 1997

Human Langerhans cells express a specific TLR profile and differentially respond to viruses and Gram-positive bacteria

scientific article published on 01 December 2006

Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional Analyses

scientific article published on 30 July 2019

Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells

scientific article

Human dendritic Langerhans cells generated in vitro from CD34+ progenitors can prime naive CD4+ T cells and process soluble antigen.

scientific article published on December 1995

Human dendritic cells can drive CD40-activated sIgD+ B cells to mount mucosal-type humoral response

scientific article published on 01 January 1995

Human dendritic cells enhance growth and differentiation of CD40 activated B cells

scientific article published on 01 January 1995

Human natural killer cells promote cross-presentation of tumor cell-derived antigens by dendritic cells

ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4(+) T cells by plasmacytoid dendritic cells

scientific article published on March 2013

ICOS-ligand expression on plasmacytoid dendritic cells supports breast cancer progression by promoting the accumulation of immunosuppressive CD4+ T cells

scientific article published in October 2012

IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer

scientific article published on 17 April 2020

IL-10 Induces CCR6 Expression During Langerhans Cell Development While IL-4 and IFN-γ Suppress It

scientific article published on November 15, 2001

Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells

scientific article

Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy

scientific article published on 26 January 2022

Immune cell dysfunctions in breast cancer patients detected through whole blood multi-parametric flow cytometry assay.

scientific article published on 10 November 2015

Immune checkpoint inhibitor treatment in patients with oncogene- addicted non-small cell lung cancer (NSCLC): summary of a multidisciplinary round-table discussion

scientific article published on 17 June 2019

Immunobiology of dendritic cells

scientific article (publication date: 2000)

Immunological and classical subtypes of oral premalignant lesions

scientific article published on 21 September 2018

Immunothérapie par ciblage des points de contrôle immunologique et thérapie cellulaire : ou comment l’une et l’autre se complètent pour un même combat

scientific article published on 01 December 2018

Impaired IFN- Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression

article

In Vitro and In Vivo Comparison of Lymphocytes Transduced with a Human CD16 or with a Chimeric Antigen Receptor Reveals Potential Off-Target Interactions due to the IgG2 CH2-CH3 CAR-Spacer

scientific article

In situ leukemic plasmacytoid dendritic cells pattern of chemokine receptors expression and in vitro migratory response

scientific article published on 01 September 2004

In vitro regulation of development and function of dendritic cells

scientific article published on 01 October 1996

In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.

scientific article published on January 2004

Infection of Human Dendritic Cells by Measles Virus Induces Immune Suppression

scientific article published on January 1, 1997

Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor.

scientific article published in December 1998

Inhibitory effect of IL-10 on human Langerhans cell antigen presenting function

scientific article published on 01 January 1995

Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment.

scientific article published on August 2012

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

scientific article published on 20 August 2019

Interferon-gamma enhances factor-dependent myeloid proliferation of human CD34+ hematopoietic progenitor cells

scientific article published on May 15, 1992

Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells.

scientific article published on August 1994

Interleukin-10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells

scientific article published on 01 April 1994

Interleukin-3 cooperates with tumor necrosis factor alpha for the development of human dendritic/Langerhans cells from cord blood CD34+ hematopoietic progenitor cells

scientific article published on 01 March 1996

Interleukin-4 has basophilic and eosinophilic cell growth-promoting activity on cord blood cells

scientific article published on January 1, 1990

Interleukin-7 induces the proliferation of normal human B-cell precursors

scientific article published on November 1, 1991

Isolation and characterization of an expressible cDNA encoding human IL-3. Induction of IL-3 mRNA in human T cell clones.

scientific article

Lymphopenia combined with low TCR diversity (divpenia) predicts poor overall survival in metastatic breast cancer patients.

scientific article

Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?

scientific article published on 28 March 2019

MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype

article published in the Proceedings of the National Academy of Sciences of the United States of America

MDR1 in immunity: friend or foe?

scientific article published on 06 September 2018

MIP-3alpha/CCL20 in renal transplantation and its possible involvement as dendritic cell chemoattractant in allograft rejection

scientific article published on 01 September 2005

Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors.

scientific article

Measles Virus Infects Human Dendritic Cells and Blocks Their Allostimulatory Properties for CD4+ T Cells

scientific article published on September 15, 1997

Modification of human long-term bone marrow cultures: establishment of a functional stromal microenvironment devoid of myeloid progenitors

scientific article published on 01 July 1992

Myofibroblastic stromal cells isolated from human bone marrow induce the proliferation of both early myeloid and B-lymphoid cells.

scientific article published in October 1993

Neoepitopes-based vaccines: challenges and perspectives

scientific article published on 12 January 2019

PAIR-gynaecology: multi/interdisciplinary for gynecologic cancer research. Problems needed to be resolved

scientific article

PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity.

scientific article published on 2 April 2015

Pathways of development of human dendritic cells

scientific article published on 01 September 1998

Patients with metastatic breast cancer leading to CD4+ T cell lymphopaenia have poor outcome

scientific article published on 19 December 2012

Pharmacological analysis of calcium responses mediated by the human A3 adenosine receptor in monocyte-derived dendritic cells and recombinant cells.

scientific article published in February 2003

Plasmacytoid dendritic cells deficient in IFNα production promote the amplification of FOXP3(+) regulatory T cells and are associated with poor prognosis in breast cancer patients.

scientific article published on January 2013

Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis

scientific article published on May 2012

Potentiation of early hematopoiesis by tumor necrosis factor-alpha is followed by inhibition of granulopoietic differentiation and proliferation

scientific article published on 01 August 1991

Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer

scientific article

Propagation of human dendritic cells in vitro

scientific article published on 01 January 2001

Quantitative and Functional Alterations of Plasmacytoid Dendritic Cells Contribute to Immune Tolerance in Ovarian Cancer

scientific article published on 22 June 2011

Recent advances in the study of dendritic cells and follicular dendritic cells.

scientific article published on January 1995

Recent successes of cancer immunotherapy: a new dimension in personalized medicine?

scientific article published on February 15, 2012

Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.

scientific article published on 6 September 2005

Recombinant human IL-3 and G-CSF act synergistically in stimulating the growth of acute myeloid leukemia cells

scientific article published on 01 March 1989

Redefining mesothelioma types as a continuum uncovers the immune and vascular systems as key players in the diagnosis and prognosis of this disease

Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

scientific article published on 24 February 2009

Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade

scientific article published on 01 October 2019

Respective involvement of TGF-beta and IL-4 in the development of Langerhans cells and non-Langerhans dendritic cells from CD34+ progenitors

scientific article published on 01 November 1999

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

scientific article

Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites

scientific article published on July 20, 1998

Selective attraction of naive and memory B cells by dendritic cells.

scientific article

Sequential loss of CD34 and class II MHC antigens on purified cord blood hematopoietic progenitors cultured with IL-3: characterization of CD34-, HLA-DR+ cells.

scientific article

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

scientific article

TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA

scientific article published on 16 July 2010

TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expression

scientific article published on 25 July 2016

TLR9 transcriptional regulation in response to double-stranded DNA viruses.

scientific article published on 5 September 2014

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

scientific article published on 06 June 2019

Targeting pattern recognition receptors in cancer immunotherapy.

scientific article published on 08 March 2012

Targeting regulatory T cells

scientific article published on February 12, 2012

The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations

scientific article

The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation

scientific article published on 01 February 1998

The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade.

scientific article published on 28 April 2017

The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12

scientific article

Tumor necrosis factor alpha cooperates with interleukin 3 in the recruitment of a primitive subset of human CD34+ progenitors

scientific article published on June 1, 1993

Tumor necrosis factor-alpha strongly potentiates interleukin-3 and granulocyte-macrophage colony-stimulating factor-induced proliferation of human CD34+ hematopoietic progenitor cells

scientific article published on June 15, 1990

Tumor promotion by intratumoral plasmacytoid dendritic cells is reversed by TLR7 ligand treatment

scientific article published on 30 May 2013

Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis.

scientific article published in June 2000

[A multidisciplinary approach to cardiac rehabilitation]

scientific article published on 01 March 2015

[Dendritic cells and gliomas: a hope in immunotherapy?].

scientific article published in December 2006

[In vitro differenciation and functions of dendritic cells obtained from CD34+ hematopoietic progenitors]

scientific article published on 01 December 1995

[Langerin: a new lectin specific for Langerhans cells induces the formation of Birbeck granules]

scientific article published on 01 July 2001

[Some important breakthroughs in oncology and hematology in 2018: A selection by the editorial board of Bulletin du Cancer]

scientific article published on 03 January 2019

[Spontaneous regression of breast cancer after biopsy. About two cases]

scientific article published on 03 January 2014