List of works - Paolo Ciana

A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver.

scientific article published on 7 December 2006

AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells.

scientific article published on 07 October 2016

Activation of brain estrogen receptors in mice lactating from mothers exposed to DDT.

scientific article

Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1.

scientific article

Cancer modeling: modern imaging applications in the generation of novel animal model systems to study cancer progression and therapy.

scientific article published on 12 March 2007

Cell cycle dependent oscillatory expression of estrogen receptor-α links Pol II elongation to neoplastic transformation

scientific article

Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor

scientific journal article

Development of a bicistronic vector for multimodality imaging of estrogen receptor activity in a breast cancer model: preliminary application

scientific article

Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPARγ Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen.

scientific article

Estrogen accelerates the resolution of inflammation in macrophagic cells

scientific article

Estrogen blocks inducible nitric oxide synthase accumulation in LPS-activated microglia cells

scientific article published on 01 December 2000

Estrogen neuroprotection: the involvement of the Bcl-2 binding protein BNIP2

scientific article published on 01 November 2001

Estrogen receptor alpha, a molecular switch converting transforming growth factor-alpha-mediated proliferation into differentiation in neuroblastoma cells

scientific article published on 22 April 2003

Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.

scientific article published on 28 July 2010

Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol

scientific article

Genistein accumulates in body depots and is mobilized during fasting, reaching estrogenic levels in serum that counter the hormonal actions of estradiol and organochlorines.

scientific article published on 3 March 2007

Genistein is an efficient estrogen in the whole-body throughout mouse development.

scientific article

Global profiling of TSEC proliferative potential by the use of a reporter mouse for proliferation.

scientific article published on 24 April 2012

HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation

scientific article published on 16 July 2010

Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland

scientific journal article

Identification of estrogen target genes in human neural cells.

scientific article

Identification of novel loci for the generation of reporter mice

scientific article

In vivo imaging of cell proliferation for a dynamic, whole body, analysis of undesired drug effects.

scientific article published on 12 March 2015

In vivo imaging of transcriptionally active estrogen receptors.

scientific article published on 16 December 2002

In vivo imaging reveals selective peroxisome proliferator activated receptor modulator activity of the synthetic ligand 3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid (MK-886).

scientific article

Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs

scientific article published on 11 February 2019

Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice.

scientific article

Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo.

scientific article published on December 1998

Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function

scientific article published on February 2002

Molecular imaging of cytochrome P450 activity in mice

scientific article published on 25 February 2012

Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals.

scientific article published on 29 February 2012

Molecular imaging, an innovative methodology for whole-body profiling of endocrine disrupter action.

scientific article published on 15 September 2008

Molecular imaging: a new way to study molecular processes in vivo.

scientific article

Novel Locally Active Estrogens Accelerate Cutaneous Wound Healing-Part 2

scientific article

Novel insights on imaging sex-hormone-dependent tumourigenesis in vivo.

scientific article published on 02 April 2011

Oestrogen Prevention of Neural Cell Death Correlates with Decreased Expression of mRNA for the Pro-Apoptotic Protein Nip-2

scientific article published on 01 November 2000

Profiling of drug action using reporter mice and molecular imaging.

scientific article published in January 2010

RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer.

scientific article published on 13 March 2018

Regulation of postnatal lung development and homeostasis by estrogen receptor beta.

scientific article published on December 2003

Reporter mice and drug discovery and development

scientific article published on 01 March 2005

Reporter mice for the study of long-term effects of drugs and toxic compounds.

scientific article published in January 2014

Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk

scientific article published on 21 December 2001

Selective Estrogen Receptor Modulators and the Tissue-Selective Estrogen Complex: Analysis of Cell Type-Specific Effects Using In Vivo Imaging of a Reporter Mouse Model

scientific article published on 01 January 2016

Target-specific action of organochlorine compounds in reproductive and nonreproductive tissues of estrogen-reporter male mice.

scientific article

Techniques: reporter mice - a new way to look at drug action.

scientific article published on June 2004

The conundrum of estrogen receptor oscillatory activity in the search for an appropriate hormone replacement therapy.

scientific article

The dynamics of estrogen receptor activity.

scientific article

The environmental chemical tributyltin chloride (TBT) shows both estrogenic and adipogenic activities in mice which might depend on the exposure dose ⬇️

scientific article published on June 12, 2011

The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferation

scientific article published on 26 October 2016

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

scientific article

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

scientific article

The v-ErbA oncoprotein quenches the activity of an erythroid-specific enhancer.

scientific article published in February 2001

Tumor cells secrete an angiogenic factor that stimulates basic fibroblast growth factor and urokinase expression in vascular endothelial cells.

scientific article

Whole body action of xenoestrogens with different chemical structures in estrogen reporter male mice.

scientific article published in December 2004

List of works by Paolo Ciana

A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver.

AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells.

Activation of brain estrogen receptors in mice lactating from mothers exposed to DDT.

Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1.

Cancer modeling: modern imaging applications in the generation of novel animal model systems to study cancer progression and therapy.

Cell cycle dependent oscillatory expression of estrogen receptor-α links Pol II elongation to neoplastic transformation

Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor

Development of a bicistronic vector for multimodality imaging of estrogen receptor activity in a breast cancer model: preliminary application

Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPARγ Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen.

Estrogen accelerates the resolution of inflammation in macrophagic cells

Estrogen blocks inducible nitric oxide synthase accumulation in LPS-activated microglia cells

Estrogen neuroprotection: the involvement of the Bcl-2 binding protein BNIP2

Estrogen receptor alpha, a molecular switch converting transforming growth factor-alpha-mediated proliferation into differentiation in neuroblastoma cells

Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.

Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol

Genistein accumulates in body depots and is mobilized during fasting, reaching estrogenic levels in serum that counter the hormonal actions of estradiol and organochlorines.

Genistein is an efficient estrogen in the whole-body throughout mouse development.

Global profiling of TSEC proliferative potential by the use of a reporter mouse for proliferation.

HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation

Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland

Identification of estrogen target genes in human neural cells.

Identification of novel loci for the generation of reporter mice

In vivo imaging of cell proliferation for a dynamic, whole body, analysis of undesired drug effects.

In vivo imaging of transcriptionally active estrogen receptors.

In vivo imaging reveals selective peroxisome proliferator activated receptor modulator activity of the synthetic ligand 3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid (MK-886).

Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs

Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice.

Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo.

Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function

Molecular imaging of cytochrome P450 activity in mice

Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals.

Molecular imaging, an innovative methodology for whole-body profiling of endocrine disrupter action.

Molecular imaging: a new way to study molecular processes in vivo.

Novel Locally Active Estrogens Accelerate Cutaneous Wound Healing-Part 2

Novel insights on imaging sex-hormone-dependent tumourigenesis in vivo.

Oestrogen Prevention of Neural Cell Death Correlates with Decreased Expression of mRNA for the Pro-Apoptotic Protein Nip-2

Profiling of drug action using reporter mice and molecular imaging.

RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer.

Regulation of postnatal lung development and homeostasis by estrogen receptor beta.

Reporter mice and drug discovery and development

Reporter mice for the study of long-term effects of drugs and toxic compounds.

Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk

Selective Estrogen Receptor Modulators and the Tissue-Selective Estrogen Complex: Analysis of Cell Type-Specific Effects Using In Vivo Imaging of a Reporter Mouse Model

Target-specific action of organochlorine compounds in reproductive and nonreproductive tissues of estrogen-reporter male mice.

Techniques: reporter mice - a new way to look at drug action.

The conundrum of estrogen receptor oscillatory activity in the search for an appropriate hormone replacement therapy.

The dynamics of estrogen receptor activity.

The environmental chemical tributyltin chloride (TBT) shows both estrogenic and adipogenic activities in mice which might depend on the exposure dose ⬇️

The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferation

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

The v-ErbA oncoprotein quenches the activity of an erythroid-specific enhancer.

Tumor cells secrete an angiogenic factor that stimulates basic fibroblast growth factor and urokinase expression in vascular endothelial cells.

Whole body action of xenoestrogens with different chemical structures in estrogen reporter male mice.