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List of works by Allen Thomas

8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors

scientific article

Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2

scientific article

Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system

scientific article

Experimental and Theoretical Kinetic Isotope Effects for Asymmetric Dihydroxylation. Evidence Supporting a Rate-Limiting “(3 + 2)” Cycloaddition

article

LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates

scientific article published on 3 September 2016

Mechanistic Pharmacokinetic-Pharmacodynamic Modeling of BACE1 Inhibition in Monkeys: Development of a Predictive Model for Amyloid Precursor Protein Processing ⬇️

scientific article published on April 12, 2013

Non-charged thiamine analogs as inhibitors of enzyme transketolase.

scientific article published on 3 December 2007

Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)

scientific article published on 10 August 2018

Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher species

scientific article

Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors

scientific article

Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.

scientific article published on 3 December 2007

The Catalytic Asymmetric Aminohydroxylation of Unsaturated Phosphonates ⬇️

scientific article published on October 29, 1999

l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan

scientific article published on 20 June 2019

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