List of works - Ali J Ryan

A novel mechanism for azoreduction

scientific article

Activation of nitrofurazone by azoreductases: multiple activities in one enzyme

scientific article

Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery

scientific article

Azoreductases in drug metabolism

scientific article published on 2 September 2016

Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues.

scientific article

Crystallographic analysis reveals the structural basis of the high-affinity binding of iophenoxic acid to human serum albumin ⬇️

scientific article

Effect of detergent on "promiscuous" inhibitors

scientific article published in July 2003

Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy

scientific article published on 19 May 2017

Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Superfamily of Enzymes

scientific article

Identification of novel members of the bacterial azoreductase family in Pseudomonas aeruginosa

scientific article

Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach

scientific article

Mechanism-based inhibition of HsaD: a C-C bond hydrolase essential for survival of Mycobacterium tuberculosis in macrophage.

scientific article published on 6 November 2013

Potential Use of the Maillard Reaction for Pharmaceutical Applications: Gastric and Intestinal Controlled Release Alginate-Albumin Beads.

scientific article published on 15 February 2019

Primary sequence contribution to the optical function of the eye lens.

scientific article published on 6 June 2014

Purification, quantification, and functional analysis of Complement Factor H.

scientific article published in January 2014

Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases

scientific article published on 28 August 2010

Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide

scientific article

Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin

scientific article

Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1.

scientific article published on 28 March 2014

Synthesis and Initial Evaluation of a Novel Fluorophore for Selective FMDV 3C Protease Detection

scientific article published on 07 August 2020

The role of apolipoprotein N-acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target.

scientific article published on 21 December 2016

List of works by Ali J Ryan

A novel mechanism for azoreduction

Activation of nitrofurazone by azoreductases: multiple activities in one enzyme

Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery

Azoreductases in drug metabolism

Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues.

Crystallographic analysis reveals the structural basis of the high-affinity binding of iophenoxic acid to human serum albumin ⬇️

Effect of detergent on "promiscuous" inhibitors

Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy

Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Superfamily of Enzymes

Identification of novel members of the bacterial azoreductase family in Pseudomonas aeruginosa

Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach

Mechanism-based inhibition of HsaD: a C-C bond hydrolase essential for survival of Mycobacterium tuberculosis in macrophage.

Potential Use of the Maillard Reaction for Pharmaceutical Applications: Gastric and Intestinal Controlled Release Alginate-Albumin Beads.

Primary sequence contribution to the optical function of the eye lens.

Purification, quantification, and functional analysis of Complement Factor H.

Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases

Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide

Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin

Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1.

Synthesis and Initial Evaluation of a Novel Fluorophore for Selective FMDV 3C Protease Detection

The role of apolipoprotein N-acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target.