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List of works by Luc Buée

1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides

scientific article

A genetic variation in the ADORA2A gene modifies age at onset in Huntington's disease.

scientific article published on 8 July 2009

A geographical cluster of progressive supranuclear palsy in northern France

scientific article

A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions

scientific article

A new decision tree combining Abeta 1-42 and p-Tau levels in Alzheimer's diagnosis.

scientific article published in May 2013

A new step towards targeting tau

scientific article published on 01 June 2019

A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors

scholarly article by Marion Gay et al published November 2018 in European Journal of Medicinal Chemistry

A walk through tau therapeutic strategies

scientific article published on 15 February 2019

A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory in a Mouse Model of Neurofibrillary Degeneration

scientific article published on 29 June 2021

A-kinase anchor protein 4 precursor (pro-AKAP4) in human spermatozoa

A2A R-induced transcriptional deregulation in astrocytes: An in vitro study

scientific article published on 22 July 2019

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

scientific article published on 2 December 2014

AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation

scientific article published on 12 October 2018

AMP-activated Protein Kinase Controls Immediate Early Genes Expression Following Synaptic Activation Through the PKA/CREB Pathway

article

AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

scientific article published on 27 May 2016

AN 88-YEAR OLD WOMAN WITH LONG-LASTING PARKINSONISM

scholarly article by Vincent Deramecourt et al published 13 June 2011 in Brain Pathology

Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis.

scientific article published in October 2002

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

article

Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms

scientific article published on 24 April 2007

Aging, but not tau pathology, impacts olfactory performances and somatostatin systems in THY-Tau22 mice.

scientific article published on 31 October 2014

Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease.

scientific article published in September 1994

Altered splicing of Tau in DM1 is different from the foetal splicing process.

scientific article

Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer's disease and progressive supranuclear palsy brains

scientific article

Alzheimer's disease risk, obesity and tau: is insulin resistance guilty?

scientific article published in May 2013

Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

scientific article

Alzheimer's disease: A beta or ApoE amyloidosis?

scientific article published in July 1995

Alzheimer's disease: the glial reaction is general and severe in all areas of the central nervous system

scientific article published in January 1989

Alzheimer-specific epitope of AT100 in transfected cell lines with tau: toward an efficient cell model of tau abnormal phosphorylation.

scientific article published on October 1998

Amyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles.

scientific article

Amyloid precursor protein reduction enhances the formation of neurofibrillary tangles in a mutant tau transgenic mouse model

scientific article published on 5 April 2017

Animal models of Alzheimer's disease: a road full of pitfalls

scientific article published in December 2005

Apolipoprotein E in Guamanian amyotrophic lateral sclerosis/ parkinsonism-dementia complex: genotype analysis and relationships to neuropathological changes

article

Are alpha-1-antichymotrypsin and inter-alpha-trypsin inhibitor peripheral markers of Alzheimer's disease?

scientific article published on May 1991

Association between caffeine intake and age at onset in Huntington's disease

scientific article

Association of plasma amyloid with risk of dementia: The prospective Three-City Study

scientific article published on 01 September 2009

Association of plasma β-amyloid with MRI markers of structural brain aging the 3-City Dijon study

scientific article

Atypical, non-standard functions of the microtubule associated Tau protein

scientific article published on 29 November 2017

Aβ1-40 and Aβ1-42 Plasmatic Levels In Stroke: Influence of Pre-Existing Cognitive Status and Stroke Characteristics

scientific article published on 27 October 2015

Beneficial Effect of a Selective Adenosine A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease

article

Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology

scientific article published on 29 March 2014

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

scientific article published on 4 May 2011

Binding of secreted human neuroblastoma proteoglycans to the Alzheimer's amyloid A4 peptide.

scientific article published in January 1993

Binding of vascular heparan sulfate proteoglycan to Alzheimer's amyloid precursor protein is mediated in part by the N-terminal region of A4 peptide

article

Biochemistry of Tau in Alzheimer's disease and related neurological disorders.

scientific article published on April 2008

Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model

scientific article published on 19 January 2019

Brain microvascular changes in Alzheimer's disease and other dementias.

scientific article published on September 1997

Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathy

scientific article published on 09 January 2014

Caffeine Consumption During Pregnancy Accelerates the Development of Cognitive Deficits in Offspring in a Model of Tauopathy

scientific article published on 01 October 2019

Central Nervous System and Peripheral Inflammatory Processes in Alzheimer's Disease: Biomarker Profiling Approach.

scientific article

Cerebral amyloid angiopathies

scientific article published in October 2000

Cerebrovascular aging

scientific article published in January 1999

Chloroquine and chloroquinoline derivatives as models for the design of modulators of amyloid Peptide precursor metabolism.

scientific article

Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.

scientific article

Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly

scientific article published on 11 May 2017

Clinical, neuropathological, and biochemical characterization of the novel tau mutation P332S.

scientific article published on January 2012

Clustering of Tau fibrils impairs the synaptic composition of α3-Na/K-ATPase and AMPA receptors

article

Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion

scientific article published on 10 May 2014

Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's disease

scientific article (publication date: October 1999)

Consensus brain-derived protein, extraction protocol for the study of human and murine brain proteome using both 2D-DIGE and mini 2DE immunoblotting. ⬇️

scientific article

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing

scientific article published on 22 November 2018

Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides

scientific article published on July 2005

Corrigendum: Somatostatin and Neuropeptide Y in Cerebrospinal Fluid: Correlations With Amyloid Peptides Aß, and Tau Proteins in Elderly Patients With Mild Cognitive Impairment

scientific article published on 19 February 2019

Current and emerging avenues for Alzheimer's disease drug targets

scientific article published on 29 August 2019

Defining the human sperm microtubulome: an integrated genomics approach

scientific article published on January 2017

Dementia beyond 2025: Knowledge and uncertainties

scientific article

Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology

scientific article published on 12 October 2018

Design and synthesis of fused tetrahydroisoquinoline-iminoimidazolines

scientific article published on 19 October 2015

Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.

scientific article published on 18 December 2012

Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer's Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies.

scientific article

Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases

scientific article published on January 1, 1992

Distribution of neurofibrillary tangles and senile plaques in the cerebral cortex in postencephalitic parkinsonism.

scientific article published in May 1992

ETR-3 represses Tau exons 2/3 inclusion, a splicing event abnormally enhanced in myotonic dystrophy type I.

scientific article published on September 2006

EVpedia: a community web portal for extracellular vesicles research

scientific article

Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.

scientific article published on April 2009

Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice

scientific article

Ectosomes: a new mechanism for non-exosomal secretion of tau protein

scientific article

Elevated circulating tumor necrosis factor levels in Alzheimer's disease ⬇️

scientific article published on August 19, 1991

Encephalopathy induced by Alzheimer brain inoculation in a non-human primate

scientific article published on 04 September 2019

Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

scientific article published on 22 June 2021

Erratum: A2A adenosine receptor deletion is protective in a mouse model of Tauopathy

article

Erratum: Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

article

EuroTau: towing scientists to tau without tautology.

scientific article

Evidence for early vulnerability of the medial and inferior aspects of the temporal lobe in an 82-year-old patient with preclinical signs of dementia. Regional and laminar distribution of neurofibrillary tangles and senile plaques

scientific article published on September 1, 1992

Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor

scientific article published on 01 November 2019

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains

scientific article published on 10 May 2010

From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

scientific article published on April 2014

From tau phosphorylation to tau aggregation: what about neuronal death?

scientific article published on August 2010

From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy

scientific article published on 04 November 2019

Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation.

scientific article

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.

scientific article

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

scientific article

Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model

scientific article published on 26 February 2019

Genome-wide Association Study Links APOEϵ4 and BACE1 Variants with Plasma Amyloid β Levels

Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions

article

Heat-treated human platelet pellet lysate modulates microglia activation, favors wound healing and promotes neuronal differentiation in vitro

scientific article published on 27 February 2020

High-Molecular-Weight Paired Helical Filaments from Alzheimer Brain Induces Seeding of Wild-Type Mouse Tau into an Argyrophilic 4R Tau Pathology in Vivo

scientific article published on 3 August 2016

Hippocampal BDNF expression in a tau transgenic mouse model.

scientific article published in May 2012

Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy

scientific article published on 5 November 2016

Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.

scientific article published on 16 December 2010

Hyperphosphorylated tau proteins differentiate corticobasal degeneration and Pick's disease

scientific article published on 01 January 1996

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis

scientific article

Immunodetection of Tau microtubule-associated protein in human sperm and testis

scientific article published in November 2014

Immunohistochemical identification of thrombospondin in normal human brain and in Alzheimer's disease ⬇️

scientific article published on October 1, 1992

Impact of the 2008-2012 French Alzheimer Plan on the use of cerebrospinal fluid biomarkers in research memory center: the PLM Study

scientific article published on January 2013

In Vivo Hyperthermic Stress Model: An Easy Tool to Study the Effects of Oxidative Stress on Neuronal Tau Functionality in Mouse Brain

scientific article published in January 2017

In vitro models of age-related neurodegenerative disorders.

scientific article published on November 2003

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

scientific journal article

Increased tauopathy drives microglia-mediated clearance of beta-amyloid.

scientific article published on 23 June 2016

Inflammatory Molecules Released by Mechanically Injured Astrocytes Trigger Presynaptic Loss in Cortical Neuronal Networks

Interleukin-1 and nerve growth factor induce hypersecretion and hypersulfation of neuroblastoma proteoglycans which bind β-amyloid

scientific article published on 01 July 1995

Intracellular pH regulates amyloid precursor protein intracellular domain accumulation.

scientific article published on 3 January 2007

Invited review: Animal models of tauopathies and their implications for research/translation into the clinic

scientific article

Juvenile frontotemporal dementia with parkinsonism associated with tau mutation G389R.

scientific article published in January 2013

Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain

scientific article published on 23 April 2013

Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin

scientific article published on 08 September 2016

Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with tau pathology?

scientific article published on September 2011

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

scientific article

MRNA Levels of ACh-Related Enzymes in the Hippocampus of THY-Tau22 Mouse: A Model of Human Tauopathy with No Signs of Motor Disturbance.

scientific article published on 23 December 2015

Mammalian Brain Ca<sup>2+</sup> Channel Activity Transplanted into <i>Xenopus laevis</i> Oocytes

scientific article published on 02 May 2022

MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy.

scientific article

MicroRNAs and the Regulation of Tau Metabolism

scientific article

Mis-splicing of Tau exon 10 in myotonic dystrophy type 1 is reproduced by overexpression of CELF2 but not by MBNL1 silencing.

scientific article

Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3beta and PKA kinase activities.

scientific article published in April 2002

Molecular actors in Alzheimer's disease: which diagnostic and therapeutic consequences?

scientific article published in September 2010

Monoaminergic neuropathology in Alzheimer's disease

scientific article published on 12 April 2016

Mutant huntingtin alters Tau phosphorylation and subcellular distribution

scientific article published on 20 August 2014

Mutual relationship between Tau and central insulin signalling: consequences for AD and Tauopathies ?

scientific article published on 13 February 2018

Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour ⬇️

scientific article published on February 11, 2013

NLRP3 inflammasome activation drives tau pathology

scientific article published on 20 November 2019

NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model.

scientific article

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease

scientific article published on August 2010

Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?

scientific article

Neurofilament ELISA validation

scientific article published on 24 October 2009

Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation

scientific article

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

scientific article published on 30 January 2014

Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice

scientific article published in 2024

Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process

scientific article published on 04 March 2019

Neuronal subpopulations and genetic background in tauopathies: a catch 22 story?

scientific article

Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model.

scientific article published in June 2012

Neurotrophic factors in Alzheimer’s disease: role of axonal transport

scientific article

New phenylaniline derivatives as modulators of amyloid protein precursor metabolism

scholarly article by Marion Gay published in May 2018

New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease

scientific article published on 27 March 2019

Normal and pathological Tau proteins as factors for microtubule assembly.

scientific article published on January 1997

Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology

scientific article published on 17 January 2020

Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation

scientific article published on 09 February 2015

Omics analysis of mouse brain models of human diseases.

scientific article

Optimization of an alcian blue dot-blot assay for the detection of glycosaminoglycans and proteoglycans ⬇️

scientific article published on June 1, 1991

Overexpression of MBNL1 fetal isoforms and modified splicing of Tau in the DM1 brain: two individual consequences of CUG trinucleotide repeats.

scientific article published on 4 December 2007

PART is part of Alzheimer disease

scientific article

PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments

scientific article

Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders

scientific article published on 01 January 1994

Pathological tau phenotypes. The weight of mutations, polymorphisms, and differential neuronal vulnerabilities.

scientific article published in January 2000

Pathological τ proteins in postencephalitic parkinsonism: Comparison with Alzheimer's disease and other neurodegenerative disorders ⬇️

scientific article published on September 1, 1997

Phosphorylation of specific sets of tau isoforms reflects different neurofibrillary degeneration processes ⬇️

scientific article published on August 21, 1998

Picalm reduction exacerbates tau pathology in a murine tauopathy model

scientific article published on 10 January 2020

Pin1 allows for differential Tau dephosphorylation in neuronal cells

scientific article published on 11 May 2006

Pin1: a therapeutic target in Alzheimer neurodegeneration

scientific article published on December 2002

Plasma amyloid levels within the Alzheimer's process and correlations with central biomarkers

scientific article published on 16 February 2018

Plasma amyloid-β levels and prognosis in incident dementia cases of the 3-City Study

scientific article published on January 2013

Plasma β-amyloid 40 levels are positively associated with mortality risks in the elderly.

scientific article published on 9 July 2014

Plasma β-amyloid and MRI markers of cerebral small vessel disease: Three-City Dijon study

scientific article published on 29 October 2014

Potential Contribution of Exosomes to the Prion-Like Propagation of Lesions in Alzheimer’s Disease ⬇️

scientific article published on July 5, 2012

Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat.

scientific article published on 14 December 2017

Prediction of pathology in primary progressive language and speech disorders.

scientific article

Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo.

scientific article published on 15 September 2015

Presenilin-1 expression in Pick's disease

scientific article published on 01 November 1999

Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody.

scientific article

Progressive age-related cognitive decline in tau mice.

scientific article published in January 2013

Proline-directed random-coil chemical shift values as a tool for the NMR assignment of the tau phosphorylation sites

scientific article published in January 2004

Proteasome inhibition and Tau proteolysis: an unexpected regulation.

scientific article

Quantitation of Alzheimer's amyloid peptide and identification of related amyloid proteins by dot-blot immunoassay

scientific article published on 01 July 1995

Rapamycin ester analog CCI-779/Temsirolimus alleviates tau pathology and improves motor deficit in mutant tau transgenic mice

scientific article published in January 2015

Rapid Tau Protein Dephosphorylation and Differential Rephosphorylation during Cardiac Arrest-Induced Cerebral Ischemia and Reperfusion

article

Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke.

scientific article published on 6 May 2014

Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation

scientific article published on 19 July 2016

Regions of tau implicated in the paired helical fragment core as defined by NMR.

scientific article

Regulation of Pin1 peptidyl-prolylcis/transisomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein

scholarly article by Caroline Smet published in July 2005

Regulation of human MAPT gene expression

scientific article published on 14 July 2015

Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator

scientific article published on 01 November 2018

Relevance of Follow-Up in Patients with Core Clinical Criteria for Alzheimer Disease and Normal CSF biomarkers

scientific article published on 9 January 2018

Reply to: Questioning the cycad theory of Kii ALS–PDC causation

scientific article published in 2024

Rescue of impaired late-phase long-term depression in a tau transgenic mouse model.

scientific article

Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms

scientific article published on 14 May 2015

Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice Studies

scientific article published on 19 August 2019

Somatostatin and Neuropeptide Y in Cerebrospinal Fluid: Correlations With Amyloid Peptides Aβ and Tau Proteins in Elderly Patients With Mild Cognitive Impairment

scientific article published on 01 October 2018

Sp3 and sp4 transcription factor levels are increased in brains of patients with Alzheimer's disease.

scientific article published on 9 October 2007

Specific pathological Tau protein variants characterize Pick's disease.

scientific article published in February 1996

Sstr2A: a relevant target for the delivery of genes into human glioblastoma cells using fiber-modified adenoviral vectors ⬇️

scientific article published on May 17, 2012

Stable-tau overexpression in human neuroblastoma cells: an open door for explaining neuronal death in tauopathies.

scientific article published on December 2003

Study of AMPK-Regulated Metabolic Fluxes in Neurons Using the Seahorse XFe Analyzer.

scientific article

Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy

scientific article

Synaptic protein dysregulation in myotonic dystrophy type 1: Disease neuropathogenesis beyond missplicing

scientific article published on 26 June 2013

Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner

scientific article

TMEM240 mutations cause spinocerebellar ataxia 21 with mental retardation and severe cognitive impairment

scientific article

Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity.

scientific article published on 7 January 2016

Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease

scientific article published on 09 November 2020

Tau and cognitive disorders: a role for T lymphocytes

scientific article published on 10 October 2017

Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?

scientific article published in February 2018

Tau as a biomarker of neurodegenerative diseases.

scientific article published on August 2008

Tau deletion promotes brain insulin resistance

scientific article

Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2.

scientific article published on 14 January 2014

Tau hyperphosphorylation induced by the anesthetic agent ketamine/xylazine involved the calmodulin-dependent protein kinase II

scientific article published on 26 December 2019

Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnostics

scientific article

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

scientific article published on 25 August 2012

Tau pathology: a marker of neurodegenerative disorders.

scientific article

Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment.

scientific article published in April 2012

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

scientific article published on 01 August 2000

Tau- but not Aß -pathology enhances NMDAR-dependent depotentiation in AD-mouse models

scientific article published on 09 December 2019

Tau/DDX6 interaction increases microRNA activity

scientific article published on 30 June 2018

The Adenosinergic Signaling: A Complex but Promising Therapeutic Target for Alzheimer's Disease

scientific article published on 03 August 2018

The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory

scientific article

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior

scientific article

The MAPT gene is differentially methylated in the progressive supranuclear palsy brain

scientific article published on 6 October 2016

The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease

article

The TMEM240 Protein, Mutated in SCA21, Is Expressed in Purkinje Cells and Synaptic Terminals

scientific article published on 30 January 2020

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.

scientific article published on 11 August 2016

The complex p25/Cdk5 kinase in neurofibrillary degeneration and neuronal death: the missing link to cell cycle.

scientific article published on August 2007

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

scientific article published on 01 March 2019

The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates

scientific article published on 31 October 2019

The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau.

scientific article published in February 2004

The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease

scientific journal article

The testicular microtubule-associated protein Tau: Where, when during spermatogenesis?

scientific article published on 20 April 2015

Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease

scientific article

Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice

scientific article published on 7 March 2003

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

scientific article

Two-Dimensional Electrophoresis Protocols to Analyze the Microtubule-Associated Tau Proteins from Several Biological Sources

scientific article published in January 2017

Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications.

scientific article published in August 1997

Two-dimensional electrophoresis of tau mutants reveals specific phosphorylation pattern likely linked to early tau conformational changes.

scientific article

Update on tauopathies.

scientific article

What is the evidence that tau pathology spreads through prion-like propagation?

scientific article published on 19 December 2017

[Biological markers in Alzheimer disease: what are the chances for less slow diagnosis?]

scientific article published on 01 April 2009

[Brain insulin signaling and Tau: impact for Alzheimer's disease and Tauopathies]

scientific article published on 01 November 2018

[Tau story: from frontotemporal dementia to other tauopathies]

scientific article published on 01 January 2002

[Tauopathy and Alzheimer disease: a full degenerating process]

scientific article published on 01 December 2006

cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases

scientific article

miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.

scientific article

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death.

scientific article published on March 2005

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