List of works - Atocha Romero

A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families

scientific article published on 3 May 2011

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

scientific article published on 16 January 2020

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

scientific article published on 18 June 2018

Assessment of Topoisomerase II α status in breast cancer by quantitative PCR, gene expression microarrays, immunohistochemistry, and fluorescence in situ hybridization

scientific article

Assignment of tumor subtype by genomic testing and pathologic-based approximations: implications on patient's management and therapy selection.

scientific article published on 2 August 2013

Association analysis identifies 65 new breast cancer risk loci.

scientific article published on 23 October 2017

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

scientific article published on 18 August 2021

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

article by Xiang Shu et al published 1 October 2018 in International Journal of Epidemiology

BRCA1 Alternative splicing landscape in breast tissue samples.

scientific article

BRCA2gene: a candidate for clinical testing in familial colorectal cancer type X

scientific article published on 18 June 2014

Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer

scientific article published on 6 September 2013

Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling

scientific article published on 01 November 2018

Capillary electrophoresis analysis of conventional splicing assays: IARC analytical and clinical classification of 31 BRCA2 genetic variants.

scientific article published on 28 October 2013

Characterization of four novel BRCA2 large genomic rearrangements in Spanish breast/ovarian cancer families: review of the literature, and reevaluation of the genetic mechanisms involved in their origin

scientific article published on 21 March 2012

Cisplatin resistance involves a metabolic reprogramming through ROS and PGC-1α in NSCLC which can be overcome by OXPHOS inhibition

scientific article published on 14 March 2019

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

scientific article published on 4 January 2022

Comparison of methods for circulating cell-free DNA isolation using blood from cancer patients: impact on biomarker testing

scientific article published on December 2016

Comprehensive annotation of splice junctions supports pervasive alternative splicing at the BRCA1 locus: a report from the ENIGMA consortium

scientific article published on 25 February 2014

Comprehensive cross-platform comparison of methods for non-invasive EGFR mutation testing: Results of the RING observational trial

scientific article published on 26 October 2020

Concordance between circulating tumor cells and clinical status during follow-up in anaplastic lymphoma kinase (ALK) non-small-cell lung cancer patients.

scientific article published on 31 July 2017

Correlation between response to neoadjuvant chemotherapy and survival in locally advanced breast cancer patients

article

Dynamic circulating tumor DNA quantificaton for the individualization of non-small-cell lung cancer patients treatment.

scientific article published on 7 August 2017

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Frequency and variability of genomic rearrangements on MSH2 in Spanish Lynch Syndrome families.

scientific article published on 11 September 2013

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

scientific article published in July 2021

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Genome-wide association study of germline variants and breast cancer-specific mortality

scientific article published on 21 February 2019

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

scientific article published on 5 October 2021

Glutathione S-transferase P1 c.313A > G polymorphism could be useful in the prediction of doxorubicin response in breast cancer patients.

scientific article published on 2 November 2011

Identification of E545k mutation in plasma from a PIK3CA wild-type metastatic breast cancer patient by array-based digital polymerase chain reaction: Circulating-free DNA a powerful tool for biomarker testing in advance disease

scientific article published on 27 April 2015

Identification of a founder EPCAM deletion in Spanish Lynch syndrome families.

scientific article

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Incorporating progesterone receptor expression into the PREDICT breast prognostic model

scientific article published in 2022

Limited family structure and triple-negative breast cancer (TNBC) subtype as predictors of BRCA mutations in a genetic counseling cohort of early-onset sporadic breast cancers.

scientific article

Liquid biopsy based biomarkers in non-small cell lung cancer for diagnosis and treatment monitoring

scientific article

Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or ovarian cancer families.

scientific article published on 05 December 2012

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

scientific article published in October 2021

Next-generation sequencing for tumor mutation quantification using liquid biopsies

scientific article published on 01 January 2020

Next-generation sequencing to dynamically detect mechanisms of resistance to ALK inhibitors in ALK-positive NSCLC patients: a case report

scientific article published on 01 April 2020

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Overall Survival and Biomarker Analysis of Neoadjuvant Nivolumab Plus Chemotherapy in Operable Stage IIIA Non–Small-Cell Lung Cancer (NADIM phase II trial)

scholarly article

PGC-1alpha levels correlate with survival in patients with stage III NSCLC and may define a new biomarker to metabolism-targeted therapy

scientific article published on 30 November 2017

Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers

scientific article published on 04 July 2014

Peritoneal washing is an adequate source for somatic BRCA1/2 mutation testing in ovarian malignancies

scientific article published on 28 October 2018

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients.

scientific article published on 16 November 2017

Sex is a strong prognostic factor in stage IV non-small-cell lung cancer patients and should be considered in survival rate estimation

scientific article published on 22 May 2020

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

Topoisomerase 2 alpha: a real predictor of anthracycline efficacy?

scientific article published on March 2012

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

scientific article published on 01 March 2020

Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging.

scientific article

Two truncating variants in FANCC and breast cancer risk

scientific article published on 29 August 2019

List of works by Atocha Romero

A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

Assessment of Topoisomerase II α status in breast cancer by quantitative PCR, gene expression microarrays, immunohistochemistry, and fluorescence in situ hybridization

Assignment of tumor subtype by genomic testing and pathologic-based approximations: implications on patient's management and therapy selection.

Association analysis identifies 65 new breast cancer risk loci.

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

BRCA1 Alternative splicing landscape in breast tissue samples.

BRCA2gene: a candidate for clinical testing in familial colorectal cancer type X

Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer

Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling

Capillary electrophoresis analysis of conventional splicing assays: IARC analytical and clinical classification of 31 BRCA2 genetic variants.

Characterization of four novel BRCA2 large genomic rearrangements in Spanish breast/ovarian cancer families: review of the literature, and reevaluation of the genetic mechanisms involved in their origin

Cisplatin resistance involves a metabolic reprogramming through ROS and PGC-1α in NSCLC which can be overcome by OXPHOS inhibition

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

Comparison of methods for circulating cell-free DNA isolation using blood from cancer patients: impact on biomarker testing

Comprehensive annotation of splice junctions supports pervasive alternative splicing at the BRCA1 locus: a report from the ENIGMA consortium

Comprehensive cross-platform comparison of methods for non-invasive EGFR mutation testing: Results of the RING observational trial

Concordance between circulating tumor cells and clinical status during follow-up in anaplastic lymphoma kinase (ALK) non-small-cell lung cancer patients.

Correlation between response to neoadjuvant chemotherapy and survival in locally advanced breast cancer patients

Dynamic circulating tumor DNA quantificaton for the individualization of non-small-cell lung cancer patients treatment.

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Frequency and variability of genomic rearrangements on MSH2 in Spanish Lynch Syndrome families.

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

Genome-wide association study of germline variants and breast cancer-specific mortality

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

Glutathione S-transferase P1 c.313A > G polymorphism could be useful in the prediction of doxorubicin response in breast cancer patients.

Identification of E545k mutation in plasma from a PIK3CA wild-type metastatic breast cancer patient by array-based digital polymerase chain reaction: Circulating-free DNA a powerful tool for biomarker testing in advance disease

Identification of a founder EPCAM deletion in Spanish Lynch syndrome families.

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Incorporating progesterone receptor expression into the PREDICT breast prognostic model

Limited family structure and triple-negative breast cancer (TNBC) subtype as predictors of BRCA mutations in a genetic counseling cohort of early-onset sporadic breast cancers.

Liquid biopsy based biomarkers in non-small cell lung cancer for diagnosis and treatment monitoring

Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or ovarian cancer families.

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

Next-generation sequencing for tumor mutation quantification using liquid biopsies

Next-generation sequencing to dynamically detect mechanisms of resistance to ALK inhibitors in ALK-positive NSCLC patients: a case report

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

Overall Survival and Biomarker Analysis of Neoadjuvant Nivolumab Plus Chemotherapy in Operable Stage IIIA Non–Small-Cell Lung Cancer (NADIM phase II trial)

PGC-1alpha levels correlate with survival in patients with stage III NSCLC and may define a new biomarker to metabolism-targeted therapy

Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers

Peritoneal washing is an adequate source for somatic BRCA1/2 mutation testing in ovarian malignancies

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients.

Sex is a strong prognostic factor in stage IV non-small-cell lung cancer patients and should be considered in survival rate estimation

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Topoisomerase 2 alpha: a real predictor of anthracycline efficacy?

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging.

Two truncating variants in FANCC and breast cancer risk