List of works - José Luis Soto

A Label Free Disposable Device for Rapid Isolation of Rare Tumor Cells from Blood by Ultrasounds.

scientific article published on 15 March 2018

Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer.

scientific article

Biallelic MYH germline mutations as cause of Muir-Torre syndrome

scientific article published on 01 June 2010

Characterization of a novel POLD1 missense founder mutation in a Spanish population

scientific article published on 17 March 2017

Circulating tumour cell analysis as an early marker for relapse in stage II and III colorectal cancer patients: a pilot study

article

Clinical and Pathological Characterization of Lynch-Like Syndrome

scientific article published on 17 June 2019

Clinically important molecular features of Peruvian colorectal tumours: high prevalence of DNA mismatch repair deficiency and low incidence of KRAS mutations

scientific article published on 01 April 2011

Co-occurrence of germline pathogenic variants for different hereditary cancer syndromes in patients with Lynch syndrome

scientific article published on 25 February 2021

Comparative genomic hybridization and amplotyping by arbitrarily primed PCR in stage A B-CLL

scientific article published on 01 October 2001

Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer

scientific article published on 25 August 2011

Consensus document on the implementation of next generation sequencing in the genetic diagnosis of hereditary cancer.

scientific article published on 10 February 2018

EPCAM germ line deletions as causes of Lynch syndrome in Spanish patients

scientific article

Functional significance of concomitant inactivation of hMLH1 and hMSH6 in tumor cells of the microsatellite mutator phenotype.

scientific article

GALNT12 is not a major contributor of familial colorectal cancer type X.

scientific article

Germline Mutations in FAN1 Cause Hereditary Colorectal Cancer by Impairing DNA Repair.

scientific article

HGUE-C-1 is an atypical and novel colon carcinoma cell line

scientific article published on 8 April 2015

Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome in Spain: Clinical and Genetic Characterization

scientific article published on 05 November 2020

Highly sensitive MLH1 methylation analysis in blood identifies a cancer patient with low-level mosaic MLH1 epimutation

scientific article published on 28 November 2019

Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines.

scientific article published on August 2005

Identification of a founder EPCAM deletion in Spanish Lynch syndrome families.

scientific article

Imaging cytometry for counting circulating tumor cells: comparative analysis of the CellSearch vs ImageStream systems ⬇️

scientific article published on March 20, 2013

Implementation of massive sequencing in the genetic diagnosis of hereditary cancer syndromes: diagnostic performance in the Hereditary Cancer Programme of the Valencia Community (FamCan-NGS)

scientific article published on 18 January 2019

Increased Risk of Colorectal Cancer in Patients With Multiple Serrated Polyps and Their First-Degree Relatives.

scientific article published on 8 April 2017

KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia.

scientific article published on 27 September 2017

Lack of cytomegalovirus detection in human glioma.

scientific article published on 7 November 2017

Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome.

scientific article

Molecular biology of exocrine pancreatic cancer.

scientific article

Multidrug resistance-associated protein (MRP1) gene is strongly expressed in gastric carcinomas. Analysis by immunohistochemistry and real-time quantitative RT-PCR.

scientific article

New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis

scientific article

Notl-Msell methylation-sensitive amplied fragment length polymorhism for DNA methylation analysis of human cancers

scientific article published on June 2001

Novel Molecular Characterization of Colorectal Primary Tumors Based on miRNAs

scientific article published on 11 March 2019

POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance

scientific article

Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines.

scientific article

Prevalence and characteristics of MUTYH-associated polyposis in patients with multiple adenomatous and serrated polyps.

scientific article published on 27 January 2014

Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers

scientific article

Prevalence of MLH1 constitutional epimutations as a cause of Lynch syndrome in unselected versus selected consecutive series of patients with colorectal cancer.

scientific article published on 23 April 2015

Prevalence of germline MUTYH mutations among Lynch-like syndrome patients

scientific article published on 18 June 2014

Primary constitutional MLH1 epimutations: a focal epigenetic event

scientific article published on 04 October 2018

Real-time PCR with internal amplification control for detecting tuberculosis: method design and validation.

scientific article published on August 2009

Recurrent Testicular Germ Cell Tumors in a Family With MYH-Associated Polyposis

scientific article published on 18 June 2012

Risk of cancer in cases of suspected lynch syndrome without germline mutation.

scientific article published on 24 January 2013

SEOM clinical guideline on hereditary colorectal cancer (2019)

scientific article published on 24 January 2020

Streptococcus gallolyticus infection in colorectal cancer and association with biological and clinical factors.

scientific article

TGFB1andTGFBR1polymorphic variants in relationship to bladder cancer risk and prognosis

scientific article published on 01 February 2009

TGFBR1 intralocus epistatic interaction as a risk factor for colorectal cancer.

scientific article

The TGFBR1*6A allele is not associated with susceptibility to colorectal cancer in a Spanish population: a case-control study.

scientific article

The heritability and patterns of DNA methylation in normal human colorectum

scientific article published on 02 March 2016

Tumour cells resistance in cancer therapy.

scientific article published on January 2007

List of works by José Luis Soto

A Label Free Disposable Device for Rapid Isolation of Rare Tumor Cells from Blood by Ultrasounds.

Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer.

Biallelic MYH germline mutations as cause of Muir-Torre syndrome

Characterization of a novel POLD1 missense founder mutation in a Spanish population

Circulating tumour cell analysis as an early marker for relapse in stage II and III colorectal cancer patients: a pilot study

Clinical and Pathological Characterization of Lynch-Like Syndrome

Clinically important molecular features of Peruvian colorectal tumours: high prevalence of DNA mismatch repair deficiency and low incidence of KRAS mutations

Co-occurrence of germline pathogenic variants for different hereditary cancer syndromes in patients with Lynch syndrome

Comparative genomic hybridization and amplotyping by arbitrarily primed PCR in stage A B-CLL

Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer

Consensus document on the implementation of next generation sequencing in the genetic diagnosis of hereditary cancer.

EPCAM germ line deletions as causes of Lynch syndrome in Spanish patients

Functional significance of concomitant inactivation of hMLH1 and hMSH6 in tumor cells of the microsatellite mutator phenotype.

GALNT12 is not a major contributor of familial colorectal cancer type X.

Germline Mutations in FAN1 Cause Hereditary Colorectal Cancer by Impairing DNA Repair.

HGUE-C-1 is an atypical and novel colon carcinoma cell line

Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome in Spain: Clinical and Genetic Characterization

Highly sensitive MLH1 methylation analysis in blood identifies a cancer patient with low-level mosaic MLH1 epimutation

Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines.

Identification of a founder EPCAM deletion in Spanish Lynch syndrome families.

Imaging cytometry for counting circulating tumor cells: comparative analysis of the CellSearch vs ImageStream systems ⬇️

Implementation of massive sequencing in the genetic diagnosis of hereditary cancer syndromes: diagnostic performance in the Hereditary Cancer Programme of the Valencia Community (FamCan-NGS)

Increased Risk of Colorectal Cancer in Patients With Multiple Serrated Polyps and Their First-Degree Relatives.

KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia.

Lack of cytomegalovirus detection in human glioma.

Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome.

Molecular biology of exocrine pancreatic cancer.

Multidrug resistance-associated protein (MRP1) gene is strongly expressed in gastric carcinomas. Analysis by immunohistochemistry and real-time quantitative RT-PCR.

New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis

Notl-Msell methylation-sensitive amplied fragment length polymorhism for DNA methylation analysis of human cancers

Novel Molecular Characterization of Colorectal Primary Tumors Based on miRNAs

POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance

Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines.

Prevalence and characteristics of MUTYH-associated polyposis in patients with multiple adenomatous and serrated polyps.

Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers

Prevalence of MLH1 constitutional epimutations as a cause of Lynch syndrome in unselected versus selected consecutive series of patients with colorectal cancer.

Prevalence of germline MUTYH mutations among Lynch-like syndrome patients

Primary constitutional MLH1 epimutations: a focal epigenetic event

Real-time PCR with internal amplification control for detecting tuberculosis: method design and validation.

Recurrent Testicular Germ Cell Tumors in a Family With MYH-Associated Polyposis

Risk of cancer in cases of suspected lynch syndrome without germline mutation.

SEOM clinical guideline on hereditary colorectal cancer (2019)

Streptococcus gallolyticus infection in colorectal cancer and association with biological and clinical factors.

TGFB1andTGFBR1polymorphic variants in relationship to bladder cancer risk and prognosis

TGFBR1 intralocus epistatic interaction as a risk factor for colorectal cancer.

The TGFBR1*6A allele is not associated with susceptibility to colorectal cancer in a Spanish population: a case-control study.

The heritability and patterns of DNA methylation in normal human colorectum

Tumour cells resistance in cancer therapy.