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List of works by Margarida Saraiva

A Nonribosomal Peptide Synthase Gene Driving Virulence in Mycobacterium tuberculosis

article

A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis

scientific article

A chemokine-binding domain in the tumor necrosis factor receptor from variola (smallpox) virus

scholarly article

A method for the generation of ectromelia virus (ECTV) recombinants: in vivo analysis of ECTV vCD30 deletion mutants

scientific article

Analysis of a local HIV-1 epidemic in portugal highlights established transmission of non-B and non-G subtypes

scientific article

BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4⁺IL-17⁺TNF⁺IL-2⁺ T cells

scientific article published on 20 November 2014

Balancing the immune response in the brain: IL-10 and its regulation

scientific article

Biology and therapeutic potential of interleukin-10

scientific article published on 01 January 2020

Chemokine binding proteins encoded by pathogens

scientific article published on January 2009

Chemokines cooperate with TNF to provide protective anti-viral immunity and to enhance inflammation.

scientific article published on 3 May 2018

Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages

scientific article published on 26 October 2016

Corticosteroid-induced immunosuppression ultimately does not compromise the efficacy of antibiotherapy in murine Mycobacterium ulcerans infection

scientific article

CrmE, a novel soluble tumor necrosis factor receptor encoded by poxviruses.

scientific article

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages

scientific article published on 22 August 2016

Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation

scientific article

Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages

scientific article

Evidence for diversifying selection in a set of Mycobacterium tuberculosis genes in response to antibiotic- and nonantibiotic-related pressure.

scientific article published on 28 February 2013

Experimental study of tuberculosis: From animal models to complex cell systems and organoids.

scientific article published on 17 August 2017

GATA-3 directly remodels the IL-10 locus independently of IL-4 in CD4+ T cells.

scientific article

Genetic variability of immunomodulatory genes in ectromelia virus isolates detected by denaturing high-performance liquid chromatography

scientific article

How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions

scientific article published on 21 May 2018

IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity

scientific article published on 4 April 2017

IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages

scientific article

Identification of a macrophage-specific chromatin signature in the IL-10 locus.

scientific article published in July 2005

Inhibition of type 1 cytokine-mediated inflammation by a soluble CD30 homologue encoded by ectromelia (mousepox) virus

scientific article

Interferon-β regulates the production of IL-10 by toll-like receptor-activated microglia

scientific article published on 15 June 2017

Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose

scientific article

L-Threonine Supplementation During Colitis Onset Delays Disease Recovery

Local and regional re-establishment of cellular immunity during curative antibiotherapy of murine Mycobacterium ulcerans infection

scientific article published on 29 February 2012

MDSCs in infectious diseases: regulation, roles, and readjustment

scientific article published on 19 December 2018

Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response

scientific article (publication date: 2013)

Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

scientific article published on 31 October 2016

Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression

scientific article

Myeloid HIF-1α regulates pulmonary inflammation during experimental Mycobacterium tuberculosis infection

scientific article published on 10 November 2019

Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control

scientific article published on 2 July 2015

P. brasiliensis virulence is affected by SconC, the negative regulator of inorganic sulfur assimilation

scientific article

Paradigm changing evidence that alter tuberculosis perception and detection: Focus on latency

article

Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis

scientific article

Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity

scientific article

TLR2 deficiency by compromising p19 (IL-23) expression limits Th 17 cell responses to Mycobacterium tuberculosis

scientific article published on 14 December 2010

TLR9 activation dampens the early inflammatory response to Paracoccidioides brasiliensis, impacting host survival

scientific article

TPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN production

scientific article published on 10 July 2013

The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferation

scientific article

The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis.

scientific article published in March 2018

The Troika Host-Pathogen-Extrinsic Factors in Tuberculosis: Modulating Inflammation and Clinical Outcomes.

scientific article published in January 2017

The regulation of IL-10 expression

scientific article published on January 2014

The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma

scientific article published on 25 August 2011

Type I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling

scientific article

Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis

scientific article published on 04 November 2020

Type I IFN induces IL-10 production in an IL-27-independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in Mycobacterium tuberculosis-infected macrophages

scientific article

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