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List of works by Patrick D Hsu

A Catalogue of Cas9 Orthologs to Advance Genome Engineering

scientific article published on 01 December 2020

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

scientific article

DNA targeting specificity of RNA-guided Cas9 nucleases

scientific article (publication date: September 2013)

Delivery and Specificity of CRISPR-Cas9 Genome Editing Technologies for Human Gene Therapy.

scientific article published on July 2015

Development and applications of CRISPR-Cas9 for genome engineering

scientific article

Dissecting neural function using targeted genome engineering technologies.

scientific article published on 19 July 2012

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity ⬇️

scientific article (publication date: 12 September 2013)

Evaluation of SARS-CoV-2 serology assays reveals a range of test performance

scientific article published on 27 August 2020

Genome engineering using the CRISPR-Cas9 system

scientific article

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

scientific article

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

scientific article

Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection

scientific article

How Has the COVID-19 Pandemic Changed How You Will Approach Research and Lab Work in the Future?

scientific article published on 01 December 2020

Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity

scientific article

Multiplex genome engineering using CRISPR/Cas systems

scientific article

Optical control of mammalian endogenous transcription and epigenetic states

scientific journal article

Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells

scientific article published in Nature Communications

Programmable RNA Targeting Using CasRx in Flies

scientific article published on 01 June 2020

Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells

scientific article published in Nature Communications

RNA-guided genome editing of mammalian cells.

scientific article published on January 2014

Rapid detection of SARS-CoV-2 with Cas13

scientific article published on 16 December 2020

Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d

scientific article published on 01 September 2018

Structure and Engineering of Francisella novicida Cas9.

scientific article published on 10 February 2016

Test performance evaluation of SARS-CoV-2 serological assays

scientific article published on 29 April 2020

Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.

scientific article published on 8 March 2018

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia

scientific article

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