List of works - Sharon M Kelly

19 A solution structure of the filarial nematode immunomodulatory protein, ES-62.

scientific article published on January 2003

3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism

scientific article published on 4 November 2002

93 The interaction of shikimate kinase fromErwinia chrystanthemiwith substrates

scientific article published on 01 November 1997

A comparative study of the structure of egg-white riboflavin binding protein from the domestic fowl and Japanese quail ⬇️

scientific article published on January 1, 1991

A heparin binding motif on the pro-domain of human procathepsin L mediates zymogen destabilization and activation

scientific article

A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress

scientific article

Activation of the acidic isoform of phospholipase A2 from Naja mossambica mossambica venom by oleoyl imidazolide requires the cooperative action of two ionizing groups

scientific article published on 01 September 1999

An Ab Initio Description of the Excitonic Properties of LH2 and Their Temperature Dependence

scientific article published on 28 October 2016

An analysis of the conformational changes that accompany the activation and inhibition of gelatinase A

scientific article published on 01 February 1996

An antiviral peptide targets a coiled-coil domain of the human T-cell leukemia virus envelope glycoprotein

scientific article

An interaction of β-amyloid with aluminium in vitro

article

Analysis of the CD23-αv integrin interaction: a study with model peptides

scientific article published on 27 April 2012

Analysis of the structural stability of the multidomain enzyme flavocytochrome P-450 BM3

article

Assembly of EcoKI DNA methyltransferase requires the C-terminal region of the HsdM modification subunit

scientific article published on 01 January 2003

Basic residues are critical to the activity of peptide inhibitors of human T cell leukemia virus type 1 entry

scientific article

Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

scientific article

Biochemical and X-ray crystallographic studies on shikimate kinase: The important structural role of the P-loop lysine

scientific article

Characterisation of a pucBA deletion mutant from Rhodopseudomonas palustris lacking all but the pucBAd genes

scientific article

Characterisation of the LH2 spectral variants produced by the photosynthetic purple sulphur bacterium Allochromatium vinosum

article

Characterization of two distinct binding modes between syntaxin 4 and Munc18c

scientific article published on 01 May 2009

Circular dichroism studies of subtilisin Carlsberg immobilised on micron sized silica particles

scientific article published on 07 April 2006

Co-operativity between modules within a C3b-binding site of complement receptor type 1

scientific article published on 01 October 1999

Combining the platinum(ii) drug candidate kiteplatin with 1,10-phenanthroline analogues

scientific article published in December 2017

Conformation of the mineralocorticoid receptor N-terminal domain: evidence for induced and stable structure

scientific article published on 4 August 2010

Conformational Changes Associated with Activation of Bee Venom Phospholipase A2

scientific article published on 01 December 1996

Conformational Studies on Plasminogen Activator Inhibitor (PAI-1) in Active, Latent, Substrate, and Cleaved Forms

scientific article published on 01 January 1995

Conformational analysis of the androgen receptor amino-terminal domain involved in transactivation. Influence of structure-stabilizing solutes and protein-protein interactions

scientific article published on 14 March 2002

Conformational changes in monoamine oxidase A in response to ligand binding or reduction

scientific article published in April 2004

Conformational changes induced by DNA binding of NF-kappa B.

scientific article

Consequences of poly-glutamine repeat length for the conformation and folding of the androgen receptor amino-terminal domain

scientific article published in September 2008

Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action

scientific article

Cytotoxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer's disease amyloid peptide, A beta 25-35.

scientific article

Discovery of a Single Monooxygenase that Catalyzes Carbamate Formation and Ring Contraction in the Biosynthesis of the Legonmycins.

scientific article published on 17 July 2015

Effects of salts on the function and conformational stability of shikimate kinase

scientific article published in May 2003

Eukaryotic localization, activation and ubiquitinylation of a bacterial type III secreted toxin

scientific article

Experimental test of absorption flattening correction for circular dichroism of particle suspensions

scientific article published on 24 June 2011

Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis

scientific journal article

Factors that govern the specificity of transglutaminase-catalysed modification of proteins and peptides ⬇️

scientific article published on March 15, 1992

Functional and structural studies on different forms of the adenylate cyclase toxin of Bordetella pertussis

scientific article

Functional characterization of a constitutively active kinase variant of Arabidopsis phototropin 1

scientific article published on 29 June 2017

Glucose Modification of Human Serum Albumin: A Structural Study

scientific article published on 01 January 1997

Health Care–AssociatedClostridium difficileInfection in Canada: Patient Age and Infecting Strain Type Are Highly Predictive of Severe Outcome and Mortality

article

Health care-associated Clostridium difficile infection in adults admitted to acute care hospitals in Canada: a Canadian Nosocomial Infection Surveillance Program Study

scientific article

Hemocyanin conformational changes associated with SDS-induced phenol oxidase activation.

scientific article published on 30 August 2007

How to study proteins by circular dichroism

scientific article

Hypervirulent Clostridium difficile strains in hospitalized patients, Canada

scientific article published in April 2010

Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach

scientific article

Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA.

scientific article

Incorporation of N-heterocyclic cations into proteins with a highly directed chemical modification

scientific article published on 29 May 2007

Induced Chirality through Electromagnetic Coupling between Chiral Molecular Layers and Plasmonic Nanostructures

scientific article published on 26 January 2012

Induced alpha-helix structure in the aryl hydrocarbon receptor transactivation domain modulates protein-protein interactions

scientific journal article

Infection control practices related to Clostridium difficile infection in acute care hospitals in Canada

scientific article

Infection prevention and control practices related to Clostridium difficile infection in Canadian acute and long-term care institutions ⬇️

scientific article published on April 1, 2011

Interaction of nitric oxide with cytochrome P450 BM3.

scientific article published in December 2004

Interdomain mobility and conformational stability of type III fibronectin domain pairs control surface adsorption, desorption and unfolding

article

Kinetics of acid-mediated disassembly of the B subunit pentamer of Escherichia coli heat-labile enterotoxin. Molecular basis of pH stability.

scientific article

LC-HRMS-Database Screening Metrics for Rapid Prioritization of Samples to Accelerate the Discovery of Structurally New Natural Products

scientific article published on 08 February 2019

Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor

scientific article

Ligand-induced Conformational States of the Cytosine-specific DNA methyltransferase M.HgaI-2

article

Localization of the Active Site of Type II Dehydroquinases

scientific article published in Journal of Biological Chemistry

Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo

scientific article published on 6 February 2015

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

article

Metal binding of Lissoclinum patella metabolites. Part 1: Patellamides A, C and ulithiacyclamide A

Metal binding of Lissoclinum patella metabolites. Part 2: Lissoclinamides 9 and 10

Molecular studies of pressure/temperature-induced structural changes in bovineβ-lactoglobulin

Multifaceted Studies of the DNA Interactions and In Vitro Cytotoxicity of Anticancer Polyaromatic Platinum(II) Complexes.

scientific article published on 24 May 2016

Mutational analysis of phototropin 1 provides insights into the mechanism underlying LOV2 signal transmission.

scientific article

NADPH oxidase activity of cytochrome P-450 BM3 and its constituent reductase domain.

scientific article

Observation of coherent delocalized phonon-like modes in DNA under physiological conditions.

scientific article

Optical spectroscopic methods for probing the conformational stability of immobilised enzymes.

scientific article

Phosphoglycerate mutase from Schizosaccharomyces pombe: development of an expression system and characterisation of three histidine mutants of the enzyme

article

Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges

scientific article

Possible role of phosphatidylserine–hemocyanin interaction in the innate immune response of Limulus polyphemus

article

Probing protein sequences as sources for encrypted antimicrobial peptides

scientific article

Probing the details of the HIV-1 Rev-Rev-responsive element interaction: effects of modified nucleotides on protein affinity and conformational changes during complex formation

scientific article published on June 1995

Raman optical activity and circular dichroism reveal dramatic differences in the influence of divalent copper and manganese ions on prion protein folding.

scientific article

Reactivation of denatured citrate synthase

scientific article published on 01 April 1992

Recombinant expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal DUF490(963-1138) domain of TamB from Escherichia coli

scientific article published on 27 August 2014

Regulation of RKIP binding to the N-region of the Raf-1 kinase

scientific article

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

scientific article

Selective modification by transglutaminase of a glutamine side chain in the hinge region of the histidine-388→glutamine mutant of yeast phosphoglycerate kinase ⬇️

scientific article published on January 1, 1991

Self-assembling multimeric integrin alpha5beta1 ligands for cell attachment and spreading.

scientific article

Sensing of remote oxyanion binding at the DNA binding domain of the molybdate-dependent transcriptional regulator, ModE.

scientific article published in September 2004

Silica Condensation by a Silicatein α Homologue Involves Surface-Induced Transition to a Stable Structural Intermediate Forming a Saturated Monolayer

scientific article published on 29 September 2010

Site-directed mutagenesis of proline 204 in the ‘hinge’ region of yeast phosphoglycerate kinase

scientific article published on 01 February 1999

Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly.

scientific article

Solution structure of the leader sequence of the patellamide precursor peptide, PatE1-34

scientific article

Specific amino acid substitutions determine the differential contribution of the N- and C-terminal domains of insulin-like growth factor (IGF)-binding protein-5 in binding IGF-I.

scientific article

Spontaneous Assembly of an Organic-Inorganic Nucleic Acid Z-DNA Double-Helix Structure

scientific article

Structural plasticity of the feline leukaemia virus fusion peptide: a circular dichroism study ⬇️

scientific article published on April 3, 1998

Structure of the atypical bacteriocin pectocin M2 implies a novel mechanism of protein uptake

scientific article published in July 2014

Structure of the bacterial plant-ferredoxin receptor FusA

scientific article

Structure-function analysis of recombinant substrate protein 22 kDa (SP-22). A mitochondrial 2-CYS peroxiredoxin organized as a decameric toroid

scientific article published on 28 May 2003

Substitution of His-181 by alanine in yeast phosphoglycerate mutase leads to cofactor-induced dissociation of the tetrameric structure.

scientific article published on April 1993

Surface activity properties of cysteine-substituted C-terminal melittin analogues

scientific article published on 01 September 1997

Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core

scientific article

Synthetic, structural and biological studies of the ubiquitin system: synthesis and crystal structure of an analogue containing unnatural amino acids.

scientific article published on May 1997

The ABA-1 allergen of the parasitic nematode Ascaris suum: fatty acid and retinoid binding function and structural characterization.

scientific article

The DNA recognition subunit of a DNA methyltransferase is predominantly a molten globule in the absence of DNA.

scientific article published in November 1994

The DvA-1 polyprotein of the parasitic nematode Dictyocaulus viviparus. A small helix-rich lipid-binding protein.

scientific article

The FAR protein family of the nematode Caenorhabditis elegans. Differential lipid binding properties, structural characteristics, and developmental regulation

scientific article

The Ov20 protein of the parasitic nematode Onchocerca volvulus. A structurally novel class of small helix-rich retinol-binding proteins.

scientific article published in November 1997

The Potassium Binding Protein Kbp Is a Cytoplasmic Potassium Sensor

scientific article

The architecture ofTrypanosoma bruceitubulin-binding cofactor B and implications for function

scientific article

The aromatic amino acid content of the bacterial chaperone protein groEL (cpn60) Evidence for the presence of a single tryptophan

scientific article published on 01 November 1991

The folding and assembly of the dodecameric type II dehydroquinases.

scientific article published on February 1999

The influence of protein solubilisation, conformation and size on the burst release from poly(lactide-co-glycolide) microspheres

scientific article

The key role of protein flexibility in modulating IgE interactions

scientific article

The membrane bound N-terminal domain of human adenosine diphosphate ribosylation factor-1 (ARF1).

scientific article published in July 2003

The molecular basis of the effect of temperature on enzyme activity

scientific article

The origin of the split B800 absorption peak in the LH2 complexes from Allochromatium vinosum

scientific article

The refolding of type II shikimate kinase from Erwinia chrysanthemi after denaturation in urea

scientific article published in April 2002

The role of the C-terminal region in phosphoglycerate mutase.

scientific article published on January 1999

The secondary structure of influenza A M2 transmembrane domain. A circular dichroism study

scientific article published on October 26, 1992

The unfolding and attempted refolding of citrate synthase from pig heart

scientific article published on 01 March 1990

The unfolding and attempted refolding of the bacterial chaperone protein groEL (cpn60)

article

The use of circular dichroism in the investigation of protein structure and function.

scientific article

Three GroEL homologues from Rhizobium leguminosarum have distinct in vitro properties

scientific article published in November 2004

Tight junction modulation and biochemical characterisation of the zonula occludens toxin C-and N-termini

scientific article published on 29 May 2007

Transglutaminase catalyses the modification of glutamine side chains in the C-terminal region of bovine beta-lactoglobulin ⬇️

scientific article published on May 1, 1992

Tunable Supramolecular Gel Properties by Varying Thermal History

scientific article published on 13 May 2019

Ultrasensitive detection and characterization of biomolecules using superchiral fields

scientific article published on 31 October 2010

Unfolding and refolding of hen egg-white riboflavin binding protein

scientific article published on 01 December 1992

Unfolding and refolding of the NAD-dependent isocitrate dehydrogenase from yeast

scientific article published on 01 April 1993

Zinc is essential for high-affinity DNA binding and recombinase activity of ΦC31 integrase

scientific article published on 20 April 2011

pH reduction as a trigger for dissociation of herpes simplex virus type 1 scaffolds

scientific article published on August 2002

pH-induced structural transitions in β-lactoglobulin

scientific article published on 01 August 1990

List of works by Sharon M Kelly

19 A solution structure of the filarial nematode immunomodulatory protein, ES-62.

3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism

93 The interaction of shikimate kinase fromErwinia chrystanthemiwith substrates

A comparative study of the structure of egg-white riboflavin binding protein from the domestic fowl and Japanese quail ⬇️

A heparin binding motif on the pro-domain of human procathepsin L mediates zymogen destabilization and activation

A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress

Activation of the acidic isoform of phospholipase A2 from Naja mossambica mossambica venom by oleoyl imidazolide requires the cooperative action of two ionizing groups

An Ab Initio Description of the Excitonic Properties of LH2 and Their Temperature Dependence

An analysis of the conformational changes that accompany the activation and inhibition of gelatinase A

An antiviral peptide targets a coiled-coil domain of the human T-cell leukemia virus envelope glycoprotein

An interaction of β-amyloid with aluminium in vitro

Analysis of the CD23-αv integrin interaction: a study with model peptides

Analysis of the structural stability of the multidomain enzyme flavocytochrome P-450 BM3

Assembly of EcoKI DNA methyltransferase requires the C-terminal region of the HsdM modification subunit

Basic residues are critical to the activity of peptide inhibitors of human T cell leukemia virus type 1 entry

Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

Biochemical and X-ray crystallographic studies on shikimate kinase: The important structural role of the P-loop lysine

Characterisation of a pucBA deletion mutant from Rhodopseudomonas palustris lacking all but the pucBAd genes

Characterisation of the LH2 spectral variants produced by the photosynthetic purple sulphur bacterium Allochromatium vinosum

Characterization of two distinct binding modes between syntaxin 4 and Munc18c

Circular dichroism studies of subtilisin Carlsberg immobilised on micron sized silica particles

Co-operativity between modules within a C3b-binding site of complement receptor type 1

Combining the platinum(ii) drug candidate kiteplatin with 1,10-phenanthroline analogues

Conformation of the mineralocorticoid receptor N-terminal domain: evidence for induced and stable structure

Conformational Changes Associated with Activation of Bee Venom Phospholipase A2

Conformational Studies on Plasminogen Activator Inhibitor (PAI-1) in Active, Latent, Substrate, and Cleaved Forms

Conformational analysis of the androgen receptor amino-terminal domain involved in transactivation. Influence of structure-stabilizing solutes and protein-protein interactions

Conformational changes in monoamine oxidase A in response to ligand binding or reduction

Conformational changes induced by DNA binding of NF-kappa B.

Consequences of poly-glutamine repeat length for the conformation and folding of the androgen receptor amino-terminal domain

Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action

Cytotoxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer's disease amyloid peptide, A beta 25-35.

Discovery of a Single Monooxygenase that Catalyzes Carbamate Formation and Ring Contraction in the Biosynthesis of the Legonmycins.

Effects of salts on the function and conformational stability of shikimate kinase

Eukaryotic localization, activation and ubiquitinylation of a bacterial type III secreted toxin

Experimental test of absorption flattening correction for circular dichroism of particle suspensions

Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis

Factors that govern the specificity of transglutaminase-catalysed modification of proteins and peptides ⬇️

Functional and structural studies on different forms of the adenylate cyclase toxin of Bordetella pertussis

Functional characterization of a constitutively active kinase variant of Arabidopsis phototropin 1

Glucose Modification of Human Serum Albumin: A Structural Study

Health Care–AssociatedClostridium difficileInfection in Canada: Patient Age and Infecting Strain Type Are Highly Predictive of Severe Outcome and Mortality

Health care-associated Clostridium difficile infection in adults admitted to acute care hospitals in Canada: a Canadian Nosocomial Infection Surveillance Program Study

Hemocyanin conformational changes associated with SDS-induced phenol oxidase activation.

How to study proteins by circular dichroism

Hypervirulent Clostridium difficile strains in hospitalized patients, Canada

Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach

Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA.

Incorporation of N-heterocyclic cations into proteins with a highly directed chemical modification

Induced Chirality through Electromagnetic Coupling between Chiral Molecular Layers and Plasmonic Nanostructures

Induced alpha-helix structure in the aryl hydrocarbon receptor transactivation domain modulates protein-protein interactions

Infection control practices related to Clostridium difficile infection in acute care hospitals in Canada

Infection prevention and control practices related to Clostridium difficile infection in Canadian acute and long-term care institutions ⬇️

Interaction of nitric oxide with cytochrome P450 BM3.

Interdomain mobility and conformational stability of type III fibronectin domain pairs control surface adsorption, desorption and unfolding

Kinetics of acid-mediated disassembly of the B subunit pentamer of Escherichia coli heat-labile enterotoxin. Molecular basis of pH stability.

LC-HRMS-Database Screening Metrics for Rapid Prioritization of Samples to Accelerate the Discovery of Structurally New Natural Products

Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor

Ligand-induced Conformational States of the Cytosine-specific DNA methyltransferase M.HgaI-2

Localization of the Active Site of Type II Dehydroquinases

Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

Metal binding of Lissoclinum patella metabolites. Part 1: Patellamides A, C and ulithiacyclamide A

Metal binding of Lissoclinum patella metabolites. Part 2: Lissoclinamides 9 and 10

Molecular studies of pressure/temperature-induced structural changes in bovineβ-lactoglobulin

Multifaceted Studies of the DNA Interactions and In Vitro Cytotoxicity of Anticancer Polyaromatic Platinum(II) Complexes.

Mutational analysis of phototropin 1 provides insights into the mechanism underlying LOV2 signal transmission.

NADPH oxidase activity of cytochrome P-450 BM3 and its constituent reductase domain.

Observation of coherent delocalized phonon-like modes in DNA under physiological conditions.

Optical spectroscopic methods for probing the conformational stability of immobilised enzymes.

Phosphoglycerate mutase from Schizosaccharomyces pombe: development of an expression system and characterisation of three histidine mutants of the enzyme

Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges

Possible role of phosphatidylserine–hemocyanin interaction in the innate immune response of Limulus polyphemus

Probing protein sequences as sources for encrypted antimicrobial peptides

Probing the details of the HIV-1 Rev-Rev-responsive element interaction: effects of modified nucleotides on protein affinity and conformational changes during complex formation

Raman optical activity and circular dichroism reveal dramatic differences in the influence of divalent copper and manganese ions on prion protein folding.

Reactivation of denatured citrate synthase

Recombinant expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal DUF490(963-1138) domain of TamB from Escherichia coli

Regulation of RKIP binding to the N-region of the Raf-1 kinase