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List of works by Marcus Järås

Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells

scientific article published on 18 October 2017

Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.

scientific article

Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells

scientific article published on 28 February 2019

CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting.

scientific article published on 28 December 2017

CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

scientific article published on 01 May 2020

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

scientific article published on April 2016

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.

scientific article

De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

scientific article published on 2 May 2018

Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage.

scientific article published on 9 January 2009

FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

scientific article published on 05 April 2019

Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

scientific article

Human short-term repopulating cells have enhanced telomerase reverse transcriptase expression.

scientific article published in August 2006

IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models.

scientific article published on 12 September 2016

IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome.

scientific article published on 12 June 2015

Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6-dependent manner

scientific article published on 18 August 2017

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

scientific article

Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.

scientific article

Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.

scientific article published on 16 June 2010

Natural Killer Cells in Myeloid Malignancies: Immune Surveillance, NK Cell Dysfunction, and Pharmacological Opportunities to Bolster the Endogenous NK Cells

scientific article published on 11 October 2019

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells

scientific article

Power cut: inhibiting mitochondrial translation to target leukemia

scientific article published on 01 November 2011

Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.

scientific article

SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function ⬇️

scientific article published on June 22, 2012

Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity

scientific article published on 05 August 2021

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