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List of works by Nigel Horscroft

An infection-based model of neurodevelopmental damage

scientific article

Antiviral applications of Toll-like receptor agonists.

scientific article published on 18 January 2012

Borna disease virus infection of adult and neonatal rats: models for neuropsychiatric disease.

scientific article published in January 2001

Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection.

scientific article published on 16 March 2011

Discovery of a highly potent series of TLR7 agonists

scientific article published on August 4, 2011

Establishment of a subgenomic replicon for bovine viral diarrhea virus in Huh-7 cells and modulation of interferon-regulated factor 3-mediated antiviral response.

scientific article published on March 2005

Investigating Toll-Like Receptor Agonists for Potential To Treat Hepatitis C Virus Infection

scientific article (publication date: August 2007)

Knockdown of USP18 increases α 2a interferon signaling and induction of interferon-stimulating genes but does not increase antiviral activity in Huh7 cells.

scientific article

Neuroprotection and reduced proliferation of microglia in ribavirin-treated bornavirus-infected rats

scientific article

Neurotrophic factor expression after CNS viral injury produces enhanced sensitivity to psychostimulants: potential mechanism for addiction vulnerability.

scientific article

Preclinical studies of PF-04849285, an interferon-α8 fusion protein for the treatment of HCV.

scientific article

The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691).

scientific article published on 30 March 2011

Therapy with TLR7 agonists induces lymphopenia: correlating pharmacology to mechanism in a mouse model.

scientific article published on 5 April 2012

Thermal denaturation of proteins for SDS-PAGE analysis by microwave irradiation

scientific article published on 01 February 1997