List of works - Théophile Ohlmann

A Rev–CBP80–eIF4AI complex drives Gag synthesis from the HIV-1 unspliced mRNA

article

A Versatile Strategy to Reduce UGA-Selenocysteine Recoding Efficiency of the Ribosome Using CRISPR-Cas9-Viral-Like-Particles Targeting Selenocysteine-tRNA[Ser]Sec Gene

scientific article published on 11 June 2019

A dormant internal ribosome entry site controls translation of feline immunodeficiency virus.

scientific article published on 30 January 2008

A fractionated reticulocyte lysate system for studies on protein synthesis initiation factors

scientific article published on 01 January 1998

A new type of IRES within gag coding region recruits three initiation complexes on HIV-2 genomic RNA

scientific article

A reevaluation of the cap-binding protein, eIF4E, as a rate-limiting factor for initiation of translation in reticulocyte lysate

scientific article published on 01 April 1996

Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression

scientific article

Back to basics: the untreated rabbit reticulocyte lysate as a competitive system to recapitulate cap/poly(A) synergy and the selective advantage of IRES-driven translation.

scientific article published on 18 September 2007

Cell-Free Protein Synthesis Enhancement from Real-Time NMR Metabolite Kinetics: Redirecting Energy Fluxes in Hybrid RRL Systems.

scientific article

Characterization of two distinct RNA domains that regulate translation of the Drosophila gypsy retroelement.

scientific article published on March 2004

Conducting the initiation of protein synthesis: the role of eIF4G.

scientific article

DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domain.

scientific article published on 21 March 2016

Different effects of the TAR structure on HIV-1 and HIV-2 genomic RNA translation.

scientific article

Effect of cleavage of the p220 subunit of eukaryotic translation initiation factor eIF-4F on protein synthesis in vitro

scientific article published on 01 May 1995

Epstein-Barr virus protein EB2 stimulates translation initiation of mRNAs through direct interactions with both PABP and eIF4G.

scientific article published on 15 November 2017

Evidence for rRNA 2'-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes.

scientific article published on 20 November 2017

Ex vivo and in vivo inhibition of human rhinovirus replication by a new pseudosubstrate of viral 2A protease.

scientific article published on 9 November 2011

Focus on Translation Initiation of the HIV-1 mRNAs ⬇️

article

Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties

scientific article

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

scientific article published in Nature Communications

HIV-1 sequences isolated from patients promote expression of shorter isoforms of the Gag polyprotein

scientific article published on 22 September 2016

HIV-2 genomic RNA accumulates in stress granules in the absence of active translation.

scientific article

HIV-2 genomic RNA contains a novel type of IRES located downstream of its initiation codon.

scientific article

Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.

scientific article

In vitro expression of the HIV-2 genomic RNA is controlled by three distinct internal ribosome entry segments that are regulated by the HIV protease and the Gag polyprotein

scientific article

Involvement of an Arginine Triplet in M1 Matrix Protein Interaction with Membranes and in M1 Recruitment into Virus-Like Particles of the Influenza A(H1N1)pdm09 Virus

scientific article

Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells

scientific article published on 27 May 2015

In vitro translation in a hybrid cell free lysate with exogenous cellular ribosomes

scientific article

In vitro translation of mRNAs that are in their native ribonucleoprotein complexes

scientific article published on 08 September 2015

In vitrostudies reveal that different modes of initiation on HIV-1 mRNA have different levels of requirement for eukaryotic initiation factor 4F

article

Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein.

scientific article

Proteolytic cleavage of initiation factor eIF-4 gamma in the reticulocyte lysate inhibits translation of capped mRNAs but enhances that of uncapped mRNAs.

scientific article

Selenium, Selenoproteins and Viral Infection

scientific article published on 04 September 2019

Subcellular localization of ENS-1/ERNI in chick embryonic stem cells.

scientific article

The 3' untranslated region of the Andes hantavirus small mRNA functionally replaces the poly(A) tail and stimulates cap-dependent translation initiation from the viral mRNA.

scientific article published on 21 July 2010

The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E.

scientific article

The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA

scientific article published on 28 April 2013

The NS1 Protein from Influenza Virus Stimulates Translation Initiation by Enhancing Ribosome Recruitment to mRNAs.

scientific article published on 19 April 2017

The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation

scientific article published on 10 October 2019

The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle

scientific article

The properties of chimeric picornavirus IRESes show that discrimination between internal translation initiation sites is influenced by the identity of the IRES and not just the context of the AUG codon.

scientific article published on June 1999

Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD

scientific article

Translation initiation is driven by different mechanisms on the HIV-1 and HIV-2 genomic RNAs.

scientific article published on 16 October 2012

Translation initiation of the HIV-1 mRNA.

scientific article

Translation of intronless RNAs is strongly stimulated by the Epstein-Barr virus mRNA export factor EB2.

scientific article published on 15 June 2009

Translation regulation of mammalian selenoproteins

scientific article published on 09 May 2018

Translational Control of the HIV Unspliced Genomic RNA

scientific article

Translational control of retroviruses.

scientific article published on February 2007

Two ribosome recruitment sites direct multiple translation events within HIV1 Gag open reading frame

scientific article

Two ribosome recruitment sites direct multiple translation events within HIV1 Gag open reading frame

article

Unlike for cellular mRNAs and other viral internal ribosome entry sites (IRESs), the eIF3 subunit e is not required for the translational activity of the HCV IRES

scientific article published on 12 January 2020

[miR-122 continues to surprise us].

scientific article published in June 2015

mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis.

scientific article published on 28 April 2016

miRNA repression of translation in vitro takes place during 43S ribosomal scanning.

scientific article published on 17 November 2012

microRNAs stimulate translation initiation mediated by HCV-like IRESes

scientific article published on 10 January 2017

List of works by Théophile Ohlmann

A Rev–CBP80–eIF4AI complex drives Gag synthesis from the HIV-1 unspliced mRNA

A Versatile Strategy to Reduce UGA-Selenocysteine Recoding Efficiency of the Ribosome Using CRISPR-Cas9-Viral-Like-Particles Targeting Selenocysteine-tRNA[Ser]Sec Gene

A dormant internal ribosome entry site controls translation of feline immunodeficiency virus.

A fractionated reticulocyte lysate system for studies on protein synthesis initiation factors

A new type of IRES within gag coding region recruits three initiation complexes on HIV-2 genomic RNA

A reevaluation of the cap-binding protein, eIF4E, as a rate-limiting factor for initiation of translation in reticulocyte lysate

Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression

Back to basics: the untreated rabbit reticulocyte lysate as a competitive system to recapitulate cap/poly(A) synergy and the selective advantage of IRES-driven translation.

Cell-Free Protein Synthesis Enhancement from Real-Time NMR Metabolite Kinetics: Redirecting Energy Fluxes in Hybrid RRL Systems.

Characterization of two distinct RNA domains that regulate translation of the Drosophila gypsy retroelement.

Conducting the initiation of protein synthesis: the role of eIF4G.

DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domain.

Different effects of the TAR structure on HIV-1 and HIV-2 genomic RNA translation.

Effect of cleavage of the p220 subunit of eukaryotic translation initiation factor eIF-4F on protein synthesis in vitro

Epstein-Barr virus protein EB2 stimulates translation initiation of mRNAs through direct interactions with both PABP and eIF4G.

Evidence for rRNA 2'-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes.

Ex vivo and in vivo inhibition of human rhinovirus replication by a new pseudosubstrate of viral 2A protease.

Focus on Translation Initiation of the HIV-1 mRNAs ⬇️

Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

HIV-1 sequences isolated from patients promote expression of shorter isoforms of the Gag polyprotein

HIV-2 genomic RNA accumulates in stress granules in the absence of active translation.

HIV-2 genomic RNA contains a novel type of IRES located downstream of its initiation codon.

Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.

In vitro expression of the HIV-2 genomic RNA is controlled by three distinct internal ribosome entry segments that are regulated by the HIV protease and the Gag polyprotein

Involvement of an Arginine Triplet in M1 Matrix Protein Interaction with Membranes and in M1 Recruitment into Virus-Like Particles of the Influenza A(H1N1)pdm09 Virus

Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells

In vitro translation in a hybrid cell free lysate with exogenous cellular ribosomes

In vitro translation of mRNAs that are in their native ribonucleoprotein complexes

In vitrostudies reveal that different modes of initiation on HIV-1 mRNA have different levels of requirement for eukaryotic initiation factor 4F

Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein.

Proteolytic cleavage of initiation factor eIF-4 gamma in the reticulocyte lysate inhibits translation of capped mRNAs but enhances that of uncapped mRNAs.

Selenium, Selenoproteins and Viral Infection

Subcellular localization of ENS-1/ERNI in chick embryonic stem cells.

The 3' untranslated region of the Andes hantavirus small mRNA functionally replaces the poly(A) tail and stimulates cap-dependent translation initiation from the viral mRNA.

The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E.

The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA

The NS1 Protein from Influenza Virus Stimulates Translation Initiation by Enhancing Ribosome Recruitment to mRNAs.

The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation

The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle

The properties of chimeric picornavirus IRESes show that discrimination between internal translation initiation sites is influenced by the identity of the IRES and not just the context of the AUG codon.

Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD

Translation initiation is driven by different mechanisms on the HIV-1 and HIV-2 genomic RNAs.

Translation initiation of the HIV-1 mRNA.

Translation of intronless RNAs is strongly stimulated by the Epstein-Barr virus mRNA export factor EB2.

Translation regulation of mammalian selenoproteins

Translational Control of the HIV Unspliced Genomic RNA

Translational control of retroviruses.

Two ribosome recruitment sites direct multiple translation events within HIV1 Gag open reading frame

Two ribosome recruitment sites direct multiple translation events within HIV1 Gag open reading frame

Unlike for cellular mRNAs and other viral internal ribosome entry sites (IRESs), the eIF3 subunit e is not required for the translational activity of the HCV IRES

[miR-122 continues to surprise us].

mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis.

miRNA repression of translation in vitro takes place during 43S ribosomal scanning.

microRNAs stimulate translation initiation mediated by HCV-like IRESes