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List of works by Maria Digiacomo

2-[(3-Methoxyphenylethyl)phenoxy]-based ABCB1 inhibitors: effect of different basic side-chains on their biological properties

scientific article published in December 2008

A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress

scientific article published on 08 August 2018

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

scientific article

Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition

scientific article published on November 2006

Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists

scientific article published on 5 June 2015

Design, synthesis and preliminary evaluation of 18F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor

scientific article published on 25 April 2015

Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma.

scientific article

Enantioselectivity in Cardioprotection induced by (S)- (−)-2,2-Dimethyl-N-(4′-acetamido-benzyl)-4-spiromorpholone-chromane

scientific article published on 01 March 2009

Evaluation of the NO-releasing properties of NO-donor linkers

scientific article published in February 2008

Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief

scientific article published on 23 July 2018

Metabolically labile cannabinoid esters: A ‘soft drug’ approach for the development of cannabinoid-based therapeutic drugs

scientific article published on 20 June 2007

NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs.

scientific article published on 27 June 2009

NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs

scientific article published in November 2004

New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design, Synthesis, and Biopharmacological Properties

scientific article published on 01 April 2006

P-gp transporter and its role in neurodegenerative diseases

scientific article published on January 2009

Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers

scientific article

SAR study on arylmethyloxyphenyl scaffold: looking for a P-gp nanomolar affinity

scientific article published on 21 February 2014

SodiumN-(Methylsulfonyl)-N-(4-nitro-2-phenoxyphenyl)sulfamate: A Water-Soluble Nimesulide Prodrug for Parenteral Use

scientific article published on 27 July 2010

Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel

scientific article

Synthesis and Affinity Evaluation for AT1 Receptor of Phenylsalicylaldoxime-Derivatives Structurally Related to Sartans

Synthesis and Biological Evaluation of 2′-Oxo-2,3-dihydro-3′H- spiro[chromene-4,5′-[1,3]oxazolidin]-3′yl]acetic Acid Derivatives as Aldose Reductase Inhibitors

scientific article published on 14 February 2011

Synthesis and biological evaluation of (hetero)arylmethyloxy- and arylmethylamine-phenyl derivatives as potent P-glycoprotein modulating agents

scientific article published on 8 February 2008

Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia

scientific article published on 13 January 2011

Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications

scientific article published on 26 December 2014

Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD.

scientific article

Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells

scientific article published on 12 August 2010

Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis

alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors

scientific article

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