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List of works by Hisato Kawakami

A comparative study of curated contents by knowledge-based curation system in cancer clinical sequencing

scientific article published on 05 August 2019

Aberrant HER3 ligand heregulin-expressing head and neck squamous cell carcinoma is resistant to anti-EGFR antibody cetuximab, but not second-generation EGFR-TKI

scientific article published on 30 September 2019

Clinical evaluation of palliative chemoradiotherapy for metastatic esophageal cancer

scientific article published on 17 May 2017

Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies

scientific article published on 05 October 2020

Comparison of S-1-cisplatin every 5 weeks with capecitabine-cisplatin every 3 weeks for HER2-negative gastric cancer (recurrent after S-1 adjuvant therapy or chemotherapy-naïve advanced): pooled analysis of HERBIS-2 (OGSG 1103) and HERBIS-4A (OGSG 1

scientific article published on 03 June 2020

Efficacy of Combination Chemotherapy Using a Novel Oral Chemotherapeutic Agent, FTD/TPI, with Ramucirumab Murine Version DC101 in a Mouse Syngeneic Cancer Transplantation Model

scientific article published on 15 December 2020

Emerging Targeted Therapies for HER2 Positive Gastric Cancer That Can Overcome Trastuzumab Resistance

scientific article published on 10 February 2020

FMS-like tyrosine kinase 3 (FLT3) amplification in patients with metastatic colorectal cancer

scientific article published on 19 October 2020

HER3 and its Ligand, Heregulin, as Targets for Cancer Therapy.

scientific article published on 18 April 2016

Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1.

scientific article published on 19 October 2016

Human epidermal growth factor eyedrops for cetuximab-related filamentary keratitis

scientific article published on 20 June 2011

Human papillomavirus DNA and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma.

scientific article published on 27 October 2013

Inhibition of EGFR, HER2 and HER3 signaling with AZD8931 alone and in combination with paclitaxel: phase i study in Japanese patients with advanced solid malignancies and advanced breast cancer.

scientific article published on 31 May 2014

Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy-induced colitis

scientific article published on 28 July 2021

Lemierre's syndrome with acute renal failure

scientific article published in December 2007

MET amplification as a potential therapeutic target in gastric cancer.

scientific article published on January 2013

MET-targeted therapy for gastric cancer: the importance of a biomarker-based strategy.

scientific article published on 21 December 2015

Microsatellite instability testing and its role in the management of colorectal cancer.

scientific article

Molecular Biomarkers in the Personalized Treatment of Colorectal Cancer.

scientific article published on 9 February 2016

Mutant BRAF Upregulates MCL-1 to Confer Apoptosis Resistance that Is Reversed by MCL-1 Antagonism and Cobimetinib in Colorectal Cancer.

scientific article published on 07 October 2016

Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts

scientific article published on 10 December 2020

Nivolumab-induced acute granulomatous tubulointerstitial nephritis in a patient with gastric cancer.

scientific article published on 6 April 2018

Phase 1 study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced solid tumors

scientific article published on 22 March 2016

Phase I trial of 5-FU, docetaxel, and nedaplatin (UDON) combination therapy for recurrent or metastatic esophageal cancer.

scientific article published on 7 June 2015

Randomized, Open-Label Phase II Study Comparing Capecitabine-Cisplatin Every 3 Weeks with S-1-Cisplatin Every 5 Weeks in Chemotherapy-Naïve Patients with HER2-Negative Advanced Gastric Cancer: OGSG1105, HERBIS-4A Trial

scientific article published on 16 August 2018

Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells.

scientific article

Risk factors for cisplatin-induced nephrotoxicity and potential of magnesium supplementation for renal protection.

scientific article

Targeting MET Amplification as a New Oncogenic Driver.

scientific article

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells

scientific article

U3-1402 sensitizes HER3-expressing tumors to PD-1 blockade by immune activation

scientific article published on 01 January 2020

Utility of circulating tumor DNA (ctDNA) versus tumor tissue clinical sequencing for enrolling patients (Pts) with advanced gastrointestinal (GI) cancer to matched clinical trials: SCRUM-Japan GI-SCREEN and GOZILA Combined Analysis

scientific article

Utility of circulating tumor DNA (ctDNA) versus tumor tissue clinical sequencing for enrolling patients (pts) with advanced non-colorectal (non-CRC) gastrointestinal (GI) cancer to matched clinical trials: SCRUM-Japan GI-SCREEN and GOZILA combined an

scientific article

Utility of circulating tumor DNA (ctDNA) versus tumor tissue genotyping for enrollment of patients with metastatic colorectal cancer (mCRC) to matched clinical trials: SCRUM-Japan GI-SCREEN and GOZILA combined analysis

scientific article

[fam-] trastuzumab deruxtecan, antitumor activity is dependent on HER2 expression level rather than on HER2 amplification

scientific article published on 24 May 2019

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