List of works - Vassilis J Demopoulos

A Diverse Series of Substituted Benzenesulfonamides as Aldose Reductase Inhibitors with Antioxidant Activity: Design, Synthesis, and in Vitro Activity ⬇️

scientific article published on November 11, 2010

A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one

scientific article

Aldose reductase enzyme and its implication to major health problems of the 21(st) century.

scientific article published on January 2009

Behavioral and antioxidant activity of a tosylbenz[g]indolamine derivative. A proposed better profile for a potential antipsychotic agent

scientific article

Bis-pyrrolyl-tetrazolyl derivatives as hybrid polar compounds: A case of lipophilic functional bioisosterism with bis-acetamides.

scientific article published on 2 February 2012

Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling.

scientific article published on 17 March 2008

Cu(II) complex of an estradiol derivative with potent anti-inflammatory properties ⬇️

scientific article published on September 1, 1991

Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation

scientific article published on 26 February 2014

Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole.

scientific article published on 11 February 2010

Development of aldose reductase inhibitors for the treatment of inflammatory disorders

scientific article published on 03 October 2013

Effect of aminoethylpyrroles on carrageenan-induced inflammation and on lipid peroxidation in rats: some structural aspects

scientific article published on 01 September 1994

Evaluation of aldose reductase inhibition and docking studies of 6'-nitro and 6',6''-dinitrorosmarinic acids.

scientific article published on 13 January 2010

Evaluation of aldose reductase inhibition and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum

scientific article

Inhibitory effect of polar oregano extracts on aldose reductase and soybean lipoxygenase in vitro

scientific article

Isomeric benzoylpyrroleacetic acids: some structural aspects for aldose reductase inhibitory and anti-inflammatory activities

scientific article published on 01 January 1995

Lipophilicity of some substituted morpholine derivatives synthesized as potential antinociceptive agents

scientific article published on 01 January 1990

Modelling of aldose reductase inhibitory activity of pyrrol-1-yl-acetic acid derivatives by means of multivariate statistics

scientific article published on 01 July 2005

Novel 1,4 substituted piperidine derivatives. Synthesis and correlation of antioxidant activity with structure and lipophilicity

scientific article published on 01 February 1995

Novel aldose reductase inhibitors: a patent survey (2006--present).

scientific article published on 24 September 2012

Proposed dopaminergic pharmacophore of lergotrile, pergolide, and related ergot alkaloid derivatives

scientific article published on 01 March 1981

Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity and selectivity

scientific article published on 11 January 2011

Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship

scientific article published on 01 December 2011

Synthesis and biological evaluation of 3-(2-aminoethyl)pyrrole derivatives

scientific article published on 01 November 1989

Synthesis of GABA-valproic acid derivatives and evaluation of their anticonvulsant and antioxidant activity

scientific article published on 01 August 1996

Synthesis of derivatives of the keto-pyrrolyl-difluorophenol scaffold: some structural aspects for aldose reductase inhibitory activity and selectivity

scientific article published on 20 December 2012

[1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone as a bioisostere of a carboxylic acid aldose reductase inhibitor

scientific article

List of works by Vassilis J Demopoulos

A Diverse Series of Substituted Benzenesulfonamides as Aldose Reductase Inhibitors with Antioxidant Activity: Design, Synthesis, and in Vitro Activity ⬇️

A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one

Aldose reductase enzyme and its implication to major health problems of the 21(st) century.

Behavioral and antioxidant activity of a tosylbenz[g]indolamine derivative. A proposed better profile for a potential antipsychotic agent

Bis-pyrrolyl-tetrazolyl derivatives as hybrid polar compounds: A case of lipophilic functional bioisosterism with bis-acetamides.

Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling.

Cu(II) complex of an estradiol derivative with potent anti-inflammatory properties ⬇️

Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation

Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole.

Development of aldose reductase inhibitors for the treatment of inflammatory disorders

Effect of aminoethylpyrroles on carrageenan-induced inflammation and on lipid peroxidation in rats: some structural aspects

Evaluation of aldose reductase inhibition and docking studies of 6'-nitro and 6',6''-dinitrorosmarinic acids.

Evaluation of aldose reductase inhibition and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum

Inhibitory effect of polar oregano extracts on aldose reductase and soybean lipoxygenase in vitro

Isomeric benzoylpyrroleacetic acids: some structural aspects for aldose reductase inhibitory and anti-inflammatory activities

Lipophilicity of some substituted morpholine derivatives synthesized as potential antinociceptive agents

Modelling of aldose reductase inhibitory activity of pyrrol-1-yl-acetic acid derivatives by means of multivariate statistics

Novel 1,4 substituted piperidine derivatives. Synthesis and correlation of antioxidant activity with structure and lipophilicity

Novel aldose reductase inhibitors: a patent survey (2006--present).

Proposed dopaminergic pharmacophore of lergotrile, pergolide, and related ergot alkaloid derivatives

Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity and selectivity

Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship

Synthesis and biological evaluation of 3-(2-aminoethyl)pyrrole derivatives

Synthesis of GABA-valproic acid derivatives and evaluation of their anticonvulsant and antioxidant activity

Synthesis of derivatives of the keto-pyrrolyl-difluorophenol scaffold: some structural aspects for aldose reductase inhibitory activity and selectivity

[1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone as a bioisostere of a carboxylic acid aldose reductase inhibitor