List of works by Kathryn J. Moore

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

scientific article published on 17 September 2002

A big role for small RNAs in HDL homeostasis.

scientific article published on 18 March 2013

A heritable netrin-1 mutation increases atherogenic immune responses

scientific article published on 10 April 2020

A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.

scientific article

A regulator of secretory vesicle size, Kelch-like protein 12, facilitates the secretion of apolipoprotein B100 and very-low-density lipoproteins--brief report

scientific article published on 12 December 2013

ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space.

scientific article published in May 2001

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

scientific article published on 17 November 2004

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

scientific article published on 5 May 2013

An Eclectic Cast of Cellular Actors Orchestrates Innate Immune Responses in the Mechanisms Driving Obesity and Metabolic Perturbation

scientific article

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

scientific article

Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress

scientific article

Atherosclerosis and innate immune signaling.

scientific article

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

scientific journal article

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

scientific article

CD36 mediates the innate host response to beta-amyloid

scientific article

CD36 signals to the actin cytoskeleton and regulates microglial migration via a p130Cas complex.

scientific article

COVID-19 and the Heart and Vasculature: Novel Approaches to Reduce Virus-Induced Inflammation in Patients With Cardiovascular Disease

scientific article published on 20 July 2020

Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells

scientific article published on 08 May 2006

Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis and Atherogenesis.

scientific article published on 27 March 2018

Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype

scientific article

Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.

scholarly article

Commentary on fatty acid wars: the diffusionists versus the translocatists.

scientific article

Connecting Transcriptional and Functional Macrophage Heterogeneity in Atherosclerosis

scientific article published on 05 December 2019

Crosstalk Between the Heart and Cancer: Beyond Drug Toxicity

scientific article published on 17 August 2020

Defining Macrophages in the Heart One Cell at a Time

scientific article published on 10 February 2019

Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling

scientific article

Designer macrophages: oxidative metabolism fuels inflammation repair

scientific article published on July 2006

Divergent response to LPS and bacteria in CD14-deficient murine macrophages.

scientific article

Dysfunctional HDL takes its toll in chronic kidney disease

scientific article published in April 2013

Emerging Roles of PCSK9: More Than a One-Trick Pony.

scientific article published on February 2016

Endothelial expression of guidance cues in vessel wall homeostasis dysregulation under proatherosclerotic conditions

scientific article published on 21 February 2013

Enhanced glycolysis and HIF-1α activation in adipose tissue macrophages sustains local and systemic interleukin-1β production in obesity

scientific article published on 27 March 2020

Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

scientific article published in Nature

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

scientific article published on 23 February 2009

Fibrillar amyloid protein present in atheroma activates CD36 signal transduction.

scientific article published on 29 December 2003

HDL and cardiovascular risk: time to call the plumber?

scientific article published on October 2012

HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells

scientific article

HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages

scientific article published on 13 February 2015

Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling

scientific article published on 11 August 2013

High-density lipoproteins put out the fire

scientific article published on February 2014

Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: mechanism for macrophage retention and survival

scientific article published on 18 April 2013

IL-1 signaling in atherosclerosis: sibling rivalry

scientific article published on 01 October 2013

IL-19 Halts Progression of Atherosclerotic Plaque, Polarizes, and Increases Cholesterol Uptake and Efflux in Macrophages

scientific article published on 4 March 2016

Immune cell screening of a nanoparticle library improves atherosclerosis therapy

scientific article

In vitro-differentiated embryonic stem cell macrophages: a model system for studying atherosclerosis-associated macrophage functions

scientific article published on 01 October 1998

Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

scientific article published on 26 June 2017

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment

scientific article published on 01 July 2005

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.

scientific article published on 19 October 2011

Introduction to the Obesity, Metabolic Syndrome, and CVD Compendium

scientific article

LDL Receptor Pathway Regulation by miR-224 and miR-520d

scientific article published on 22 May 2020

LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.

scientific article published on 19 August 2015

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.

scientific article published on May 2009

Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation

scientific article

Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity

scientific article

Local Anti-miR Delivery: The Latest in the Arsenal of Drug-Eluting Stents.

scientific article

Long non-coding RNAs regulating macrophage functions in homeostasis and disease

Long noncoding RNAs in lipid metabolism.

scientific article published on 16 March 2018

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

scientific article published on 23 October 2008

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

scientific article

Macrophage Foam Cell Formation: The Pathways to Cholesterol Engorgement

Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis

scientific article

Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)

scientific article published on 01 October 2018

Macrophage-derived foam cells in atherosclerosis: lessons from murine models and implications for therapy.

scientific article published on December 2007

Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells

scientific article published in Nature Communications

Macrophages in atherosclerosis: a dynamic balance.

scientific article

Macrophages in the pathogenesis of atherosclerosis

scientific article (publication date: 29 April 2011)

Macrophages, atherosclerosis and the potential of netrin-1 as a novel target for future therapeutic intervention

scientific article published on May 2012

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

scientific article

MiR-33 contributes to the regulation of cholesterol homeostasis.

scientific article

MicroRNA Regulation of Atherosclerosis

scientific article published on February 2016

MicroRNA control of high-density lipoprotein metabolism and function

scientific article

MicroRNA modulation of cholesterol homeostasis

scientific article

MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging

scientific article

MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

scientific article

MicroRNAs in lipid metabolism

scientific article

MicroRNAs regulating lipid metabolism in atherogenesis

scientific article published on 25 January 2012

Modulation of ambient temperature promotes inflammation and initiates atherosclerosis in wild type C57BL/6 mice

scientific article published on 21 September 2016

Molecular Pathways Underlying Cholesterol Homeostasis.

scientific article published on 13 June 2018

Monocyte Adhesion and Plaque Recruitment During Atherosclerosis Development Is Regulated by the Adapter Protein Chat-H/SHEP1

scientific article published on 14 July 2016

MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4.

scientific article

Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21

scientific article published on 01 January 2020

Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism

scientific article published on 18 April 2016

Myocardial infarction accelerates breast cancer via innate immune reprogramming

scientific article published on 13 July 2020

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

scientific article (publication date: 29 April 2010)

Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity

scientific article published on 07 August 2019

Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis

scientific article published on 8 August 2016

Netrin-1 inhibits leukocyte migration in vitro and in vivo.

scientific article

Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation

scientific article

Netrin-1 is highly expressed and required in inflammatory infiltrates in wear particle-induced osteolysis.

scientific article published on 9 October 2015

Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.

scientific article published on 02 March 2014

Neuroimmune guidance cue Semaphorin 3E is expressed in atherosclerotic plaques and regulates macrophage retention

scientific article published on 21 February 2013

Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association

scientific article published on 29 June 2020

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

scientific article

Oxidation of low-density lipoproteins induces amyloid-like structures that are recognized by macrophages.

scientific article

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

scientific article (publication date: October 1999)

Phagocytosis and phagosome acidification are required for pathogen processing and MyD88-dependent responses to Staphylococcus aureus

scientific article

Platelet regulation of myeloid suppressor of cytokine signaling 3 accelerates atherosclerosis

scientific article published on 01 November 2019

Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages

scientific article published on 29 March 2016

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

scientific article published on 14 March 2004

Regulation of Stress Granule Formation by Inflammation, Vascular Injury, and Atherosclerosis

scientific article published on 29 August 2019

Regulation of macrophage immunometabolism in atherosclerosis

scientific article published on 18 May 2018

Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression

scientific article published on 27 April 2020

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis

scientific article published in November 2004

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

scientific journal article

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

scientific article

Role of toll-like receptor 4 in intimal foam cell accumulation in apolipoprotein E-deficient mice

scientific article

Scavenger receptor CD36 mediates uptake of high density lipoproteins in mice and by cultured cells

scientific article published on 9 January 2011

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

scientific article

Scavenger receptors in atherosclerosis: beyond lipid uptake

scientific article

Selective uptake of HDL cholesteryl esters and cholesterol efflux from mouse peritoneal macrophages independent of SR-BI.

scientific article published on 22 August 2006

Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications

scientific article published on 13 July 2007

Single step reconstitution of multifunctional high-density lipoprotein-derived nanomaterials using microfluidics.

scientific article

Single-Cell RNA Sequencing of Visceral Adipose Tissue Leukocytes Reveals that Caloric Restriction Following Obesity Promotes the Accumulation of a Distinct Macrophage Population with Features of Phagocytic Cells

scientific article published on 19 July 2019

Small RNA overcomes the challenges of therapeutic targeting of microsomal triglyceride transfer protein

scientific article

Store-Operated Ca2+ Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism

scientific article

Targeting Innate Immunity for CV Benefit

scientific article published on January 2008

Targeting inflammation in CVD: advances and challenges

scientific article published on 01 February 2019

The Semaphorin 3E/PlexinD1 axis regulates macrophage inflammation in obesity

scientific article published in October 2013

The double-edged sword of fibronectin in atherosclerosis

scientific article

The long noncoding RNA CHROME regulates cholesterol homeostasis in primate

scientific article published on 03 December 2018

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

scientific article published on 8 January 2012

The plaque "micro" environment: microRNAs control the risk and the development of atherosclerosis.

scientific article published on October 2012

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

scientific article

The role of microRNAs in cholesterol efflux and hepatic lipid metabolism.

scientific article published on August 2011

Untangling the role of amyloid in atherosclerosis.

scientific article published on October 2006

Using microRNA as an alternative treatment for hyperlipidemia and cardiovascular disease: cardio-miRs in the pipeline

scientific article

Vascular effects of a low-carbohydrate high-protein diet.

scientific article published on 24 August 2009

Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation

scientific article published on 24 April 2017

beta-Amyloid promotes accumulation of lipid peroxides by inhibiting CD36-mediated clearance of oxidized lipoproteins

scientific article

eLiXiRs for restraining inflammation

scientific article published on 01 February 2003

miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques

scientific article

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

scientific article

miR33 inhibition overcomes deleterious effects of diabetes mellitus on atherosclerosis plaque regression in mice.

scientific article

miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux

scientific article published on 3 March 2016

microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis

scientific article published on 20 April 2017

microRNAs and cholesterol metabolism

scientific article

microRNAs: small regulators with a big impact on lipid metabolism.

scientific article published on 9 March 2013

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