List of works - Lutz Tautz

A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase

scientific article

A highly convergent synthesis of myristoyl-carba(dethia)-coenzyme A.

scientific article published on March 2010

A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.

scientific article

Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases

scientific article

Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.

scientific article published on 8 April 2008

Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis ⬇️

scientific article

Evaluating effects of tyrosine phosphatase inhibitors on T cell receptor signaling.

scientific article published on January 2013

High-throughput screening for protein tyrosine phosphatase activity modulators.

scientific article published on January 2013

In silico screening for PTPN22 inhibitors: active hits from an inactive phosphatase conformation

scientific article

Inhibition of Lymphoid Tyrosine Phosphatase by Benzofuran Salicylic Acids ⬇️

scientific article published on December 29, 2010

Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation

scientific article published on 17 November 2011

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease

scientific article (publication date: August 2014)

LYP inhibits T-cell activation when dissociated from CSK.

scientific article

Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.

scientific article published on 4 April 2015

Protein tyrosine phosphatases in autoimmunity.

scientific article published on January 2008

Protein tyrosine phosphatases: structure, function, and implication in human disease.

scientific article published on January 2013

TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses

scientific article published on 05 May 2008

The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses.

scientific article

Visualizing Active-Site Dynamics in Single Crystals of HePTP: Opening of the WPD Loop Involves Coordinated Movement of the E Loop

scientific article

List of works by Lutz Tautz

A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase

A highly convergent synthesis of myristoyl-carba(dethia)-coenzyme A.

A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.

Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases

Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.

Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis ⬇️

Evaluating effects of tyrosine phosphatase inhibitors on T cell receptor signaling.

High-throughput screening for protein tyrosine phosphatase activity modulators.

In silico screening for PTPN22 inhibitors: active hits from an inactive phosphatase conformation

Inhibition of Lymphoid Tyrosine Phosphatase by Benzofuran Salicylic Acids ⬇️

Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease

LYP inhibits T-cell activation when dissociated from CSK.

Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.

Protein tyrosine phosphatases in autoimmunity.

Protein tyrosine phosphatases: structure, function, and implication in human disease.

TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses

The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses.

Visualizing Active-Site Dynamics in Single Crystals of HePTP: Opening of the WPD Loop Involves Coordinated Movement of the E Loop