List of works - Philip L Johnson

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

scientific article published in February 2018

A functional subset of serotonergic neurons in the rat ventrolateral periaqueductal gray implicated in the inhibition of sympathoexcitation and panic.

scientific article published in June 2004

A key role for orexin in panic anxiety.

scientific article

A selective orexin-1 receptor antagonist attenuates stress-induced hyperarousal without hypnotic effects

scientific article

A selective, non-peptide CRF receptor 1 antagonist prevents sodium lactate-induced acute panic-like responses.

scientific article published on 19 November 2010

Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia.

scientific article

Acute carbon dioxide exposure in healthy adults: evaluation of a novel means of investigating the stress response.

scientific article published in March 2004

Anatomic and functional topography of the dorsal raphe nucleus

scientific article published in June 2004

Angiotensin II's role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic.

scientific article published on 21 March 2013

Angiotensin-II is a putative neurotransmitter in lactate-induced panic-like responses in rats with disruption of GABAergic inhibition in the dorsomedial hypothalamus.

scientific article published in September 2006

Are tuberomammillary histaminergic neurons involved in CO2-mediated arousal?

scientific article published in May 2005

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

scientific article published on 16 February 2012

Changes in central sodium and not osmolarity or lactate induce panic-like responses in a model of panic disorder

scientific article

Chronic inhibition of GABA synthesis in the bed nucleus of the stria terminalis elicits anxiety-like behavior

scientific article

Corrigendum to "Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model" [Psychoneuroendocrinology 65 (2016) 127-137]

scientific article published on 03 September 2016

Disruption of GABAergic tone in the dorsomedial hypothalamus attenuates responses in a subset of serotonergic neurons in the dorsal raphe nucleus following lactate-induced panic.

scientific article

Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient

scientific article

Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells.

scientific article published on 16 March 2017

Etiology, triggers and neurochemical circuits associated with unexpected, expected, and laboratory-induced panic attacks

scientific article

Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation.

scientific article

Evaluation of Low versus High Volume per Minute Displacement CO₂ Methods of Euthanasia in the Induction and Duration of Panic-Associated Behavior and Physiology.

scientific article

From QTL to candidate gene: a genetic approach to alcoholism research

scientific article

Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats.

scientific article

Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model

scientific article published on 18 December 2015

Local inhibition of organic cation transporters increases extracellular serotonin in the medial hypothalamus.

scientific article published on 2 November 2005

Modulation of anxiety circuits by serotonergic systems.

scientific article

Multiple anxiogenic drugs recruit a parvalbumin-containing subpopulation of GABAergic interneurons in the basolateral amygdala.

scientific article published on 18 July 2010

Neural pathways underlying lactate-induced panic.

scientific article

Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal-pituitary axis activity or hyperthermia.

scientific article

OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO2 -INDUCED PANIC-ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES.

scientific article published on 19 August 2015

Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network.

scientific article

PSD95 and nNOS interaction as a novel molecular target to modulate conditioned fear: relevance to PTSD

scientific article published on 14 August 2018

Panic results in unique molecular and network changes in the amygdala that facilitate fear responses

scientific article published on 14 August 2018

Panic-prone state induced in rats with GABA dysfunction in the dorsomedial hypothalamus is mediated by NMDA receptors.

scientific article published in June 2006

Pharmacological depletion of serotonin in the basolateral amygdala complex reduces anxiety and disrupts fear conditioning.

scientific article

Repeated stimulation of CRF receptors in the BNST of rats selectively induces social but not panic-like anxiety.

scientific article

Role of medial hypothalamic orexin system in panic, phobia and hypertension

scientific article published on 08 September 2018

Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs.

scientific article published in January 2005

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase

scientific journal article

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex

scientific article published on 5 June 2011

Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential.

scientific article published on September 2016

The Deakin/Graeff hypothesis: focus on serotonergic inhibition of panic

scientific article

The role of the medial prefrontal cortex in regulating social familiarity-induced anxiolysis.

scientific article

Topographical distribution of corticotropin-releasing factor type 2 receptor-like immunoreactivity in the rat dorsal raphe nucleus: co-localization with tryptophan hydroxylase

scientific journal article

Using loss- and gain-of-function approaches to target amygdala-projecting serotonergic neurons in the dorsal raphe nucleus that enhance anxiety-related and conditioned fear behaviors

scientific article published on 10 March 2020

List of works by Philip L Johnson

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

A functional subset of serotonergic neurons in the rat ventrolateral periaqueductal gray implicated in the inhibition of sympathoexcitation and panic.

A key role for orexin in panic anxiety.

A selective orexin-1 receptor antagonist attenuates stress-induced hyperarousal without hypnotic effects

A selective, non-peptide CRF receptor 1 antagonist prevents sodium lactate-induced acute panic-like responses.

Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia.

Acute carbon dioxide exposure in healthy adults: evaluation of a novel means of investigating the stress response.

Anatomic and functional topography of the dorsal raphe nucleus

Angiotensin II's role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic.

Angiotensin-II is a putative neurotransmitter in lactate-induced panic-like responses in rats with disruption of GABAergic inhibition in the dorsomedial hypothalamus.

Are tuberomammillary histaminergic neurons involved in CO2-mediated arousal?

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

Changes in central sodium and not osmolarity or lactate induce panic-like responses in a model of panic disorder

Chronic inhibition of GABA synthesis in the bed nucleus of the stria terminalis elicits anxiety-like behavior

Corrigendum to "Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model" [Psychoneuroendocrinology 65 (2016) 127-137]

Disruption of GABAergic tone in the dorsomedial hypothalamus attenuates responses in a subset of serotonergic neurons in the dorsal raphe nucleus following lactate-induced panic.

Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient

Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells.

Etiology, triggers and neurochemical circuits associated with unexpected, expected, and laboratory-induced panic attacks

Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation.

Evaluation of Low versus High Volume per Minute Displacement CO₂ Methods of Euthanasia in the Induction and Duration of Panic-Associated Behavior and Physiology.

From QTL to candidate gene: a genetic approach to alcoholism research

Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats.

Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model

Local inhibition of organic cation transporters increases extracellular serotonin in the medial hypothalamus.

Modulation of anxiety circuits by serotonergic systems.

Multiple anxiogenic drugs recruit a parvalbumin-containing subpopulation of GABAergic interneurons in the basolateral amygdala.

Neural pathways underlying lactate-induced panic.

Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal-pituitary axis activity or hyperthermia.

OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO2 -INDUCED PANIC-ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES.

Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network.

PSD95 and nNOS interaction as a novel molecular target to modulate conditioned fear: relevance to PTSD

Panic results in unique molecular and network changes in the amygdala that facilitate fear responses

Panic-prone state induced in rats with GABA dysfunction in the dorsomedial hypothalamus is mediated by NMDA receptors.

Pharmacological depletion of serotonin in the basolateral amygdala complex reduces anxiety and disrupts fear conditioning.

Repeated stimulation of CRF receptors in the BNST of rats selectively induces social but not panic-like anxiety.

Role of medial hypothalamic orexin system in panic, phobia and hypertension

Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs.

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex

Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential.

The Deakin/Graeff hypothesis: focus on serotonergic inhibition of panic

The role of the medial prefrontal cortex in regulating social familiarity-induced anxiolysis.

Topographical distribution of corticotropin-releasing factor type 2 receptor-like immunoreactivity in the rat dorsal raphe nucleus: co-localization with tryptophan hydroxylase

Using loss- and gain-of-function approaches to target amygdala-projecting serotonergic neurons in the dorsal raphe nucleus that enhance anxiety-related and conditioned fear behaviors