List of works - Niki L Reynaert

A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.

scientific article

Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice

scientific article published on April 2016

Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling

scientific article

Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease

scientific article published on 29 June 2016

Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells

scientific article published on 16 April 2016

Altered cigarette smoke-induced lung inflammation due to ablation of Grx1

scientific article

Association of glutathione-S-transferase omega haplotypes with susceptibility to chronic obstructive pulmonary disease.

scientific article

Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD.

scientific article published on 25 February 2014

Catalase overexpression fails to attenuate allergic airways disease in the mouse

scientific article

Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants

scientific article published on 27 March 2017

Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition.

scientific article

Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death.

scientific article published on 31 March 2011

Decreased plasma sRAGE levels in COPD: influence of oxygen therapy

scientific article published on 31 January 2012

Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

scientific article

Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

scientific article

Early origins of lung disease: towards an interdisciplinary approach

scientific article published on 01 September 2020

Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice

scientific article published on 19 February 2015

Efficacy of IFN-λ1 to protect human airway epithelial cells against human rhinovirus 1B infection

scientific article

Emerging mechanisms of glutathione-dependent chemistry in biology and disease

scientific article published on September 2013

Glutathione biochemistry in asthma

scientific article published on 31 January 2011

Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling Reviewed

scientific article

In situ detection and visualization of S-nitrosylated proteins following chemical derivatization: identification of Ran GTPase as a target for S-nitrosylation

scientific article

In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization.

scientific article published on 20 February 2006

Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics.

scientific article published on February 2013

Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease

scientific article published on 8 December 2016

Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells

scientific article

Interferon-β induces a long-lasting antiviral state in human respiratory epithelial cells

scientific article published on 28 November 2012

Involvement of c-Jun N-Terminal Kinase in TNF-α-Driven Remodeling

scientific article published on 22 November 2016

Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease

scientific article published on 15 September 2006

Nitric oxide and redox signaling in allergic airway inflammation

scientific article

Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation

scholarly article

Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control

scientific article published on May 2009

Plasma advanced glycation end-products and skin autofluorescence are increased in COPD.

scientific article published on 3 May 2013

Protocols for the detection of s-glutathionylated and s-nitrosylated proteins in situ

scientific article published on 20 June 2010

RAPID PULMONARY EXPRESSION OF ACUTE-PHASE REACTANTS AFTER LOCAL LIPOPOLYSACCHARIDE EXPOSURE IN MICE IS FOLLOWED BY AN INTERLEUKIN-6 MEDIATED SYSTEMIC ACUTE-PHASE RESPONSE

article

Reactive nitrogen species and cell signaling: implications for death or survival of lung epithelium

scientific article

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.

scientific article published on January 2009

Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway

scientific article published on September 2006

Regulation of apoptosis through cysteine oxidation: implications for fibrotic lung disease.

scientific article published on August 2010

SOD inactivation in asthma: bad or no news?

scientific article

Selective IL-1α exposure to the fetal gut, lung, and chorioamnion/skin causes intestinal inflammatory and developmental changes in fetal sheep.

scientific article published on 26 October 2015

Silica induces NLRP3 inflammasome activation in human lung epithelial cells

scientific article published on 12 February 2013

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

scientific article

Similar matrix alterations in alveolar and small airway walls of COPD patients

scientific article

Smoke decreases reversible oxidations S-glutathionylation and S-nitrosylation in mice

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.

scientific article published on 6 August 2015

Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection?

scientific article published on December 2009

Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease

scientific article published in October 2013

The effects of dexamethasone and oxygen in ventilated adult sheep with early phase acute respiratory distress syndrome

scientific article published on 13 December 2014

Thiol redox chemistry: role of protein cysteine oxidation and altered redox homeostasis in allergic inflammation and asthma

scientific article

Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD.

scientific article

List of works by Niki L Reynaert

A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.

Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice

Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling

Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease

Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells

Altered cigarette smoke-induced lung inflammation due to ablation of Grx1

Association of glutathione-S-transferase omega haplotypes with susceptibility to chronic obstructive pulmonary disease.

Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD.

Catalase overexpression fails to attenuate allergic airways disease in the mouse

Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants

Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition.

Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death.

Decreased plasma sRAGE levels in COPD: influence of oxygen therapy

Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

Early origins of lung disease: towards an interdisciplinary approach

Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice

Efficacy of IFN-λ1 to protect human airway epithelial cells against human rhinovirus 1B infection

Emerging mechanisms of glutathione-dependent chemistry in biology and disease

Glutathione biochemistry in asthma

Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling Reviewed

In situ detection and visualization of S-nitrosylated proteins following chemical derivatization: identification of Ran GTPase as a target for S-nitrosylation

In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization.

Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics.

Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease

Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells

Interferon-β induces a long-lasting antiviral state in human respiratory epithelial cells

Involvement of c-Jun N-Terminal Kinase in TNF-α-Driven Remodeling

Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease

Nitric oxide and redox signaling in allergic airway inflammation

Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation

Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control

Plasma advanced glycation end-products and skin autofluorescence are increased in COPD.

Protocols for the detection of s-glutathionylated and s-nitrosylated proteins in situ

RAPID PULMONARY EXPRESSION OF ACUTE-PHASE REACTANTS AFTER LOCAL LIPOPOLYSACCHARIDE EXPOSURE IN MICE IS FOLLOWED BY AN INTERLEUKIN-6 MEDIATED SYSTEMIC ACUTE-PHASE RESPONSE

Reactive nitrogen species and cell signaling: implications for death or survival of lung epithelium

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.

Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway

Regulation of apoptosis through cysteine oxidation: implications for fibrotic lung disease.

SOD inactivation in asthma: bad or no news?

Selective IL-1α exposure to the fetal gut, lung, and chorioamnion/skin causes intestinal inflammatory and developmental changes in fetal sheep.

Silica induces NLRP3 inflammasome activation in human lung epithelial cells

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

Similar matrix alterations in alveolar and small airway walls of COPD patients

Smoke decreases reversible oxidations S-glutathionylation and S-nitrosylation in mice

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.

Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection?

Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease

The effects of dexamethasone and oxygen in ventilated adult sheep with early phase acute respiratory distress syndrome

Thiol redox chemistry: role of protein cysteine oxidation and altered redox homeostasis in allergic inflammation and asthma

Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD.